ID H8YL93_AERHY Unreviewed; 213 AA.
AC H8YL93;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 03-MAY-2023, entry version 33.
DE RecName: Full=Thiol:disulfide interchange protein {ECO:0000256|PIRNR:PIRNR001488};
OS Aeromonas hydrophila.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=644 {ECO:0000313|EMBL:AFD54047.1};
RN [1] {ECO:0000313|EMBL:AFD54047.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=AH-3 {ECO:0000313|EMBL:AFD54047.1};
RX PubMed=22198000; DOI=10.1016/j.micpath.2011.10.006;
RA Vilches S., Jimenez N., Merino S., Tomas J.M.;
RT "The Aeromonas dsbA mutation decreased their virulence by triggering type
RT III secretion system but not flagella production.";
RL Microb. Pathog. 52:130-139(2012).
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418,
CC ECO:0000256|PIRNR:PIRNR001488}.
CC -!- SIMILARITY: Belongs to the thioredoxin family. DsbA subfamily.
CC {ECO:0000256|ARBA:ARBA00005791}.
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DR EMBL; JF747155; AFD54047.1; -; Genomic_DNA.
DR AlphaFoldDB; H8YL93; -.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd03019; DsbA_DsbA; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR001853; DSBA-like_thioredoxin_dom.
DR InterPro; IPR023205; DsbA/DsbL.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR35891; THIOL:DISULFIDE INTERCHANGE PROTEIN DSBA; 1.
DR PANTHER; PTHR35891:SF2; THIOL:DISULFIDE INTERCHANGE PROTEIN DSBA; 1.
DR Pfam; PF01323; DSBA; 1.
DR PIRSF; PIRSF001488; Tdi_protein; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRNR:PIRNR001488};
KW Periplasm {ECO:0000256|ARBA:ARBA00022764, ECO:0000256|PIRNR:PIRNR001488};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..213
FT /note="Thiol:disulfide interchange protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003617496"
FT DOMAIN 19..160
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT DISULFID 61..64
FT /note="Redox-active"
FT /evidence="ECO:0000256|PIRSR:PIRSR001488-1"
SQ SEQUENCE 213 AA; 23831 MW; F8C0DB2317B2CA87 CRC64;
MPHSDPLTGN VMKKVLFFLA AMLMIPMVHA APEFKEGVNY DVVKQTGSAQ PEVLEFFSYY
CPHCAKFEPI AADLKKNLPE GVPMKKNPVA FLGREMGPEM QRAYAVASLL NVEGKLTPAI
FDKIHTQRQY PQSRTDVKQI FVDNGVPAEE FDGAVDSFAV SGMVSQFDRN TESYNIRGVP
AFLVNGKYMV KIESITSQEQ FNQLVKFLLA KKD
//
