ID H9AY02_ECOLX Unreviewed; 242 AA.
AC H9AY02;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 03-MAY-2023, entry version 25.
DE SubName: Full=IncX type IV secretion system protein VirB8 {ECO:0000313|EMBL:AFC60917.1};
GN Name=virB8 {ECO:0000313|EMBL:AFC60917.1};
GN ORFNames=ec14_29 {ECO:0000313|EMBL:AFC60917.1};
OS Escherichia coli.
OG Plasmid pEC14_35 {ECO:0000313|EMBL:AFC60917.1}.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=562 {ECO:0000313|EMBL:AFC60917.1};
RN [1] {ECO:0000313|EMBL:AFC60917.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=EC14 {ECO:0000313|EMBL:AFC60917.1};
RC PLASMID=pEC14_35 {ECO:0000313|EMBL:AFC60917.1};
RX PubMed=22470007; DOI=10.1016/j.plasmid.2012.03.001;
RA Johnson T.J., Bielak E.M., Fortini D., Hansen L.H., Hasman H., Debroy C.,
RA Nolan L.K., Carattoli A.;
RT "Expansion of the IncX plasmid family for improved identification and
RT typing of novel plasmids in drug-resistant Enterobacteriaceae.";
RL Plasmid 68:43-50(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JN935899; AFC60917.1; -; Genomic_DNA.
DR RefSeq; WP_015059075.1; NZ_VKYF01000047.1.
DR RefSeq; YP_006953688.1; NC_019083.1.
DR AlphaFoldDB; H9AY02; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd16424; VirB8; 1.
DR Gene3D; 3.10.450.230; VirB8 protein; 1.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR007430; VirB8.
DR Pfam; PF04335; VirB8; 1.
DR SUPFAM; SSF54427; NTF2-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Plasmid {ECO:0000313|EMBL:AFC60917.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..239
FT /note="Bacterial virulence protein VirB8"
FT /evidence="ECO:0000259|Pfam:PF04335"
SQ SEQUENCE 242 AA; 27409 MW; ACF994D089B32BA4 CRC64;
MGFKLSELKL PGFNKKKEVT DSSTTFEEKN VLMQEKMNRI YKFGGIAGMA VGVLSLLALN
GALPLKSTVV EAYLINGVTG VAERLTSVKK ENLSENEALA KYFITQYVKR REGYNYFSLQ
HDYDYVLLYS AENVATDYNA LINSNQSPKV IYNKAEKTAS VQDNPSVIIS PSSRRDDKDM
GAYVRFKLTI RNVATGQDDY EYWNVRLTYR IEPQVEMASG DRNNNPLKFV VTSYVRDKEV
KG
//
