ID H9F5U9_MACMU Unreviewed; 1473 AA.
AC H9F5U9;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=Plexin-B2 {ECO:0000313|EMBL:AFE70008.1};
DE Flags: Fragment;
GN Name=PLXNB2 {ECO:0000313|EMBL:AFE70008.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:AFE70008.1};
RN [1] {ECO:0000313|EMBL:AFE70008.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Caudate {ECO:0000313|EMBL:AFE70008.1};
RX PubMed=25319552; DOI=10.1186/1745-6150-9-20;
RA Zimin A.V., Cornish A.S., Maudhoo M.D., Gibbs R.M., Zhang X., Pandey S.,
RA Meehan D.T., Wipfler K., Bosinger S.E., Johnson Z.P., Tharp G.K.,
RA Marcais G., Roberts M., Ferguson B., Fox H.S., Treangen T., Salzberg S.L.,
RA Yorke J.A., Norgren R.B.Jr.;
RT "A new rhesus macaque assembly and annotation for next-generation
RT sequencing analyses.";
RL Biol. Direct 9:20-20(2014).
CC -!- SIMILARITY: Belongs to the plexin family.
CC {ECO:0000256|ARBA:ARBA00010297}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR EMBL; JU326252; AFE70008.1; -; mRNA.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0017154; F:semaphorin receptor activity; IEA:InterPro.
DR CDD; cd01180; IPT_plexin_repeat1; 1.
DR CDD; cd01179; IPT_plexin_repeat2; 1.
DR CDD; cd12792; RasGAP_plexin_B2; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR031148; Plexin.
DR InterPro; IPR013548; Plexin_cytoplasmic_RasGAP_dom.
DR InterPro; IPR046800; Plexin_RBD.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR041019; TIG1_plexin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR22625; PLEXIN; 1.
DR PANTHER; PTHR22625:SF9; PLEXIN-B2; 1.
DR Pfam; PF08337; Plexin_cytopl; 1.
DR Pfam; PF20170; Plexin_RBD; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR Pfam; PF01833; TIG; 2.
DR Pfam; PF17960; TIG_plexin; 1.
DR SMART; SM00429; IPT; 3.
DR SMART; SM00423; PSI; 3.
DR SUPFAM; SSF81296; E set domains; 3.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 2: Evidence at transcript level;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 1..101
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFE70008.1"
SQ SEQUENCE 1473 AA; 165682 MW; 76F21B9A7F128A55 CRC64;
SEHLPYPLGS RDGLKATAVL QRGGLNLTAV TVTAENNHTV AFLGTSDGRI LKVYLTPNGT
SSEYDSILVE INKRVKRDLV LSGDLASLYA MTQDKVFRLP VQECLSYPTC TQCRDSQDPY
CGWCVVEGRC TRKAECPRAE EASHWLWSRS KSCVAITSAQ PQNMSRRAQG EVQLTVSPLP
ALSKEDELLC LFGESPPHPA RVEGGTVICN SPSSIPITPP GQDHVAVTIQ LLLRRDNIFL
TSYKYPFYDC RQAMSLEENL PCISCVSNRW TCQWDLRYHE CREASPNPED GIIRAHMEDS
CPQFLEPSPL VIPMNHETDV TFQGKNLDTV KGSSLHVGSD LLKFMEPVSM QESGTFVFRT
PKLSHDANET LPLHLYVKSY GKNIDSKLHV TLYNCSFGRS DCSLCQAAHP DYRCAWCGGQ
SRCVYEALCN ATSECPPPVI TRIQPETGPL GGGIRITILG SNLGVRAEDI QRISVAGRNC
AFQPESYSVS TRIVCVIEAA EAPFTGGVEV DVFGKLGHSP PNVQFTFQQP QPLSVEPQQG
PQAGGTTLTI HGTYLDTGSQ EDVRVTLNGI PCKVTKFGAQ LQCVTGPQAT RGQMPLEVSY
GGSPVPSSSI FFTYRENPVL RAFEPLRSFA SGGRSINVTG QGFSLIQRFA MVVIAEPLQS
WQPPREAESL QPVTVVGMDY VFHNDTKVVF LSPAVPEEPE AYNLTVLIEM DGHRALLRTE
AGAFEYVPDP TFENFTGGVK KQVNKLIHAR GTNLNKAMTL QEAEAFVGAE RCTMKTLTET
DLYCEPPEVQ PPPKRRQKRD TTHNLPEFIV KFGSREWVLG RVEYDTRVSD VPLSLILPLV
IVPMVVVIAV SVYCYWRKSQ QAEREYEKIK SQLEGLEESV RDRCKKEFTD LMIEMEDQTN
DVHEAGIPVL DYKTYTDRVF FLPSKDGDKD VMITGKLDIP EPRRPVVEQA LYQFSNLLNS
KSFLINFIHT LENQREFSAR AKVYFASLLT VALHGKLEYY TDIMRTLFLE LLEQYVVAKN
PKLMLRRSET VVERMLSNWM SICLYQYLKD SAGEPLYKLF KAIKHQVEKG PVDAVQKKAK
YTLNDTGLLG DDVEYAPLTV SVIVQDEGVD AIPVKVLNCD TISQVKEKII DQVYRGQPCS
CWPRPDSVVL EWRPGSTAQI LSDLDLTSQR EGRWKRVNTL MHYNVRDGAT LILSKVGVSQ
QPEDSQQDLP GERHALLEEE NRVWHLVRPT DEVDEGKSKR GSVKEKERTK AITEIYLTRL
LSVKGTLQQF VDNFFQSVLA PGHAVPPAVK YFFDFLDEQA EKHNIQDEDT IHIWKTNSLP
LRFWVNILKN PHFIFDVHVH EVVDASLSVI AQTFMDACTR TEHKLSRDSP SNKLLYAKEI
STYKKMVEDY YKGIRQMVQV SDQDMNTHLA EISRAHTDSL NTLVALHQLY QYTQKYYDEI
INALEEDPAA QKMQLAFRLQ QIAAALENKV TDL
//
