ID H9F9N2_MACMU Unreviewed; 1278 AA.
AC H9F9N2;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Neuronal cell adhesion molecule isoform A {ECO:0000313|EMBL:AFE71341.1};
DE Flags: Fragment;
GN Name=NRCAM {ECO:0000313|EMBL:AFE71341.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:AFE71341.1};
RN [1] {ECO:0000313|EMBL:AFE71341.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Caudate {ECO:0000313|EMBL:AFE71341.1};
RX PubMed=25319552; DOI=10.1186/1745-6150-9-20;
RA Zimin A.V., Cornish A.S., Maudhoo M.D., Gibbs R.M., Zhang X., Pandey S.,
RA Meehan D.T., Wipfler K., Bosinger S.E., Johnson Z.P., Tharp G.K.,
RA Marcais G., Roberts M., Ferguson B., Fox H.S., Treangen T., Salzberg S.L.,
RA Yorke J.A., Norgren R.B.Jr.;
RT "A new rhesus macaque assembly and annotation for next-generation
RT sequencing analyses.";
RL Biol. Direct 9:20-20(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily.
CC L1/neurofascin/NgCAM family. {ECO:0000256|ARBA:ARBA00008588}.
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DR EMBL; JU327585; AFE71341.1; -; mRNA.
DR AlphaFoldDB; H9F9N2; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 5.
DR CDD; cd05868; Ig4_NrCAM; 1.
DR CDD; cd05874; IgI_NrCAM; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 11.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR026966; Neurofascin/L1/NrCAM_C.
DR PANTHER; PTHR44170:SF15; NEURONAL CELL ADHESION MOLECULE; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF13882; Bravo_FIGEY; 1.
DR Pfam; PF00041; fn3; 5.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 3.
DR SMART; SM00060; FN3; 5.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 6.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50853; FN3; 5.
DR PROSITE; PS50835; IG_LIKE; 6.
PE 2: Evidence at transcript level;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1143..1164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..108
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 115..209
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 241..330
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 335..422
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 428..515
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 519..606
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 623..718
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 720..817
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 822..924
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 928..1024
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1038..1130
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1173..1278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1173..1229
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFE71341.1"
SQ SEQUENCE 1278 AA; 140997 MW; 94C08D0442C5DF65 CRC64;
ISALEVPLDP KLLEDLVQPP TITQQSPKDY IIDPRENIVI QCEAKGKPPP SFSWTRNGTH
FDIDKDPLVT MKPGTGTLII NIMSEGKAET YEGVYQCTAR NERGAAISNN IVVRPSRSPL
WTKEKLEPIT LQSGQSLVLP CRPPIGLPPP IIFWMDNSFQ RLPQSERVSQ GLNGDLYFSN
VLPEDTREDY ICYARFNHTQ TIQQKQPISV KVISVDELND TIAANLSDTE FYGAKSSRER
PPTFLTPEGN ASNKEELRGN VLSLECIAEG LPTPIIYWAK EDGMLPKNRT VYKNFEKTLQ
IIHVSEADSG NYQCIAKNAL GAIHHTISVR VKAAPYWITA PQNLVLSPGE DGTLICRANG
NPKPRISWLT NGVPIEIAPD DPSRKIDGDT IIFSNVQERS SAVYQCNASN EYGYLLANAF
VNVLAEPPRI LTPANTLYQV IANRPALLDC AFFGSPLPTI EWFKGAKGSA LHEDIYVLHE
NGTLEIPVAQ KDSTGTYTCV ARNKLGMAKN EVHLEIKDPT WIIKQPEYAV VQRGSMVSFE
CKVKHDYTLT LTVLWLKDNR ELPSDERFTV DKDHLVIADV SDNDSGTYTC VANTTLDSVS
ASAVLSVVAP TPTPAPVYDV PNPPFDLELT DQLDKSVQLS WTPGDDNNSP ITKFIIEYED
TMHEPGLWHH QTEVSGTQTT AQLKLSPYVN YSFRVMAVNS IGKSLPSEAS EQYLTKASEP
DKNPTAVEGL GSEPDNLVIT WKPLNGFESN GPGLQYKVSW RQKDGDDEWT SVVVANVSKY
IVSGTPTFVP YLIKVQALND VGFAPEPAVV MGHSGEDLPM VAPGNVRVNV VNSTLAEVHW
DPVPLKSIRG HLQGYRIYYW KTQSSSKRNR RHIEKKILTF QGSKTHGMLP GLEPFSHYTL
NVRVVNGKGE GPASPDRVFN TPEGVPSAPS SLKIVNPTLD SLTLEWHPPS HPNGILTEYT
LKYQPINSTH ELGPLVDLKI PANKTRWTLK NLNFSTRYKF YFYAQTSAGS GSQITEEAVT
TMDEAGILPP DVGAGKVQAV NPRISNLTAA AAETYANISW EYEGPQHVNF YVEYGVAGSK
EEWRKEIVNG SRSFFGLKGL MPGTAYKVRV GAVGDSGFVS SEDVFETGPA MASRQVDIAT
QGWFIGLMCA VALLILILLI VCFIRRNKGG KYPVKEKEDA HADPEIQPMK EDDGTFGEYS
DAEDHKPLKK GSRTPSDRTV KKEDSDDSLV DYGEGVNGQF NEDGSFIGQY SGKKEKEPAE
GNESSEAPSP VNAMNSFV
//
