ID H9FQM7_MACMU Unreviewed; 889 AA.
AC H9FQM7;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 16-MAY-2012, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Schlafen family member 5 {ECO:0000313|EMBL:AFE76936.1};
GN Name=SLFN5 {ECO:0000313|EMBL:AFE76936.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:AFE76936.1};
RN [1] {ECO:0000313|EMBL:AFE76936.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Caudate {ECO:0000313|EMBL:AFE76936.1};
RX PubMed=25319552; DOI=10.1186/1745-6150-9-20;
RA Zimin A.V., Cornish A.S., Maudhoo M.D., Gibbs R.M., Zhang X., Pandey S.,
RA Meehan D.T., Wipfler K., Bosinger S.E., Johnson Z.P., Tharp G.K.,
RA Marcais G., Roberts M., Ferguson B., Fox H.S., Treangen T., Salzberg S.L.,
RA Yorke J.A., Norgren R.B.Jr.;
RT "A new rhesus macaque assembly and annotation for next-generation
RT sequencing analyses.";
RL Biol. Direct 9:20-20(2014).
CC -!- SIMILARITY: Belongs to the Schlafen family. Subgroup III subfamily.
CC {ECO:0000256|ARBA:ARBA00010114}.
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DR EMBL; JU333181; AFE76936.1; -; mRNA.
DR AlphaFoldDB; H9FQM7; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.30.950.30; Schlafen, AAA domain; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR031450; Poxin-SLFN/SLFN_N.
DR InterPro; IPR029684; Schlafen.
DR InterPro; IPR007421; Schlafen_AlbA_2_dom.
DR InterPro; IPR038461; Schlafen_AlbA_2_dom_sf.
DR InterPro; IPR018647; SLFN_3-like_DNA/RNA_helicase.
DR InterPro; IPR048729; SLFN_GTPase-like.
DR PANTHER; PTHR12155; SCHLAFEN; 1.
DR PANTHER; PTHR12155:SF26; SCHLAFEN FAMILY MEMBER 5; 1.
DR Pfam; PF17057; B3R; 1.
DR Pfam; PF09848; SLFN-g3_helicase; 1.
DR Pfam; PF04326; SLFN_AlbA_2; 1.
DR Pfam; PF21026; SLFN_GTPase-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 2: Evidence at transcript level;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 80..189
FT /note="Poxin-Schlafen/Schlafen-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17057"
FT DOMAIN 191..305
FT /note="Schlafen AlbA-2"
FT /evidence="ECO:0000259|Pfam:PF04326"
FT DOMAIN 384..519
FT /note="Schlafen GTPase-like"
FT /evidence="ECO:0000259|Pfam:PF21026"
FT DOMAIN 574..688
FT /note="Schlafen group 3-like DNA/RNA helicase"
FT /evidence="ECO:0000259|Pfam:PF09848"
SQ SEQUENCE 889 AA; 100944 MW; A13F3F9073882895 CRC64;
MSLRIDSNTN FPECVVDAGK VILGTRWRQE MDPRLREKQN EIILQAVCAL LNSGGGIIKA
EIENKGYNYE SHGVGLDVPP IFRSHLDEMQ QENHFLIFVK SWNTEAGVPL ATLCSNLYHR
QRTSTDVMDS QEALAFLKRR TQSLTNINVS NSLSPQAAQS SVQYEGNTKA LAAALFDRKR
LQYLEKLNFP ESKHVEFVMF STDVSHRVKD RLPKCVSALA NTEGGYVFFG VHDGTCQVIG
CEKEKIDLTS LRASIDGCIK KLPVHHFCTQ RPEIQYVLNF LEVHDKGALR GYVCAIKVEQ
FCCAVFAKAP SSWQVKDNRV RQLPTREWTA WMMEADPDLS RCPEMVLALS LSSATPRSKT
VCIHKNLERL KEQQKRYFPV FSDRVVYTPE SLYKELFSQH KGLRDLINTE MRPFSQGILI
FSQSWAVDLG LQEKQGVICD ALLISQNNTP ILYTIFSKWD AGCKGYSMVV AYSLKQKLVN
KGGYTGRLCI TPLVCVLNSD RKAQSVCGSY LQIYPESYNF MTPQHMEALL QSLVIVLLGF
KSFLSEELGS EVLNLLTNKQ YELLSKNLRK TKELFVHGLP GSGKTILALK IMEKIKNVFH
CEPTDILYIC ENYPLKKLVS KKNICQPVTR KTFMKNNFER VQHIVIDDAQ NFRTEDGDWY
GKAKFITQTA RDGPGVLWIF LDYFQTNHLS CSGLPPLSDQ YPREEITRVV RSADPIANYL
QQIMQEARQN LPPNLPPGSL VMLYEPKWAQ GVPGNLEIIE DLNLEEILVY VADKCRFLLQ
NGYSPRDIAV LFTKASEVEK YKDRLLTAMR KRKMSQLDEE CDLLLQVGDA LDVLTNHIVL
DSVCRFSGLE RNIVFGINPG VTQQAGVYNL LLCLASRAKR HLYILKASV
//
