ID H9G7Z8_ANOCA Unreviewed; 1164 AA.
AC H9G7Z8;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Tenascin C {ECO:0000313|Ensembl:ENSACAP00000003647.3};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000003647.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000003647.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000003647.3};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000003647.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR AlphaFoldDB; H9G7Z8; -.
DR STRING; 28377.ENSACAP00000003647; -.
DR Ensembl; ENSACAT00000003736.4; ENSACAP00000003647.3; ENSACAG00000003431.4.
DR eggNOG; KOG1225; Eukaryota.
DR eggNOG; KOG2579; Eukaryota.
DR GeneTree; ENSGT00940000155188; -.
DR HOGENOM; CLU_001162_0_0_1; -.
DR TreeFam; TF329915; -.
DR Proteomes; UP000001646; Unplaced.
DR Bgee; ENSACAG00000003431; Expressed in adrenal gland and 9 other cell types or tissues.
DR GO; GO:0062023; C:collagen-containing extracellular matrix; IBA:GO_Central.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0030155; P:regulation of cell adhesion; IBA:GO_Central.
DR CDD; cd00063; FN3; 9.
DR CDD; cd00087; FReD; 1.
DR Gene3D; 2.20.25.10; -; 1.
DR Gene3D; 3.90.215.10; Gamma Fibrinogen, chain A, domain 1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR036056; Fibrinogen-like_C.
DR InterPro; IPR014716; Fibrinogen_a/b/g_C_1.
DR InterPro; IPR002181; Fibrinogen_a/b/g_C_dom.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR NCBIfam; NF040941; GGGWT_bact; 1.
DR PANTHER; PTHR46708; TENASCIN; 1.
DR PANTHER; PTHR46708:SF1; TENASCIN; 1.
DR Pfam; PF00147; Fibrinogen_C; 1.
DR Pfam; PF00041; fn3; 10.
DR SMART; SM00186; FBG; 1.
DR SMART; SM00060; FN3; 10.
DR SUPFAM; SSF56496; Fibrinogen C-terminal domain-like; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 8.
DR PROSITE; PS51406; FIBRINOGEN_C_2; 1.
DR PROSITE; PS50853; FN3; 9.
PE 4: Predicted;
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Secreted {ECO:0000256|ARBA:ARBA00022530}.
FT DOMAIN 37..127
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 128..218
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 219..307
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 308..399
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 489..581
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 582..671
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 672..761
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 762..851
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 852..940
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 938..1153
FT /note="Fibrinogen C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51406"
SQ SEQUENCE 1164 AA; 128599 MW; 7A01BC68EC20E576 CRC64;
MQIGLAPGQQ YNVSLYVVKN QTRGPGLSKI VTTRLDAPSQ IEAKDVTDTT ALITWFKPLA
EIDGVELTYG PKSSPGDRTS IDLSEDESQF SIGNLKPHTE YEVTLTSRRG DMESDPVTET
FVTDLDAPRN LKRLSQTDNT ITLEWKNSEA TPEMYRIKYA PISGGDHIEV TVPRSNQATT
KATLTGLRPG TEYGIGVTAV KEDKESAPAT INAGTDLDSP KDLEVTDPTE TTLTLRWKRP
LAKIDRYRLS YLTPSGRKNE IEIPVDSTSY ILRSLDAGVE YTINLVAEKG RHKSKPSTVT
GTTEEEPELG NLSVSKVHWD GFQLTWTAAD GAYESFIIQV REPNLPEDAR NLTIPGGLRS
VDLTGLLPNT LYTITLYGVT QGYRTKPLLV ESTTAAKPDV GDLTISGITP ESFNLSWTAT
NQAFEMFTIE IIDSNRLLEP KVYNVSGNLR TAHISGLSPK TDFIVYLYGV TNGFRSQTLS
AAATTVEPLL SKLTVSNVTF DGLSLQWKAQ DFAFDNFLLE VRNTNNQSLD SQLHTVPGSI
RSFVLTKLRP SSSYHLQIHG LVDGQSSQTL TALATTGISS PILDNLLVSD ATPHGFRLSW
TADDGAFDSF VLKIRAANML SDPLELIVPG HERTQDIIGL KEGMEYYIDL YGVTSGRRSQ
PVNAIATTAM GSPKDITFSD ITENSAMVSW TAPVARVDNY RITYVPVTGG PPSSVTVDGN
KSRTRLARLI PGVEYTVSII SVKGFEESEP VSGSFITALD SPSGLKAVNI TESEALAVWQ
PAIAAVDEYV ISYITDGGKS TPEVTQSVSG NTVEYDLFDL RPASEYTLRI YAIKDSQKSR
IISTKFTTAL DAPKDLTTTD VQSETALVKW KPPRAPVTGY LLTYESIDGR LKEVILGPES
TSYGLSDLSP STQYIVKLQA LNLNLRSKII QAVFTTTGLL YPYPRDCSQA LLNGETTSGL
YTIYLNGDQS QPVEVYCDMT SDGGGWIVFL RRQNGAEDFY RNWRTYEAGF GDPKGEFWMG
LDKLHKITSA AQYELRVDLR DHGETAYALY EKFTVGDSRT RYRLKVDGYS GTAGDSMTYH
NGRSFSTYDK DNDSAITNCA LSYKGAFWYK NCHRVNLMGR YGDNSHSQGV NWFHWKGHEY
SIQFAEMKLR PYSFRNLEGR RKRA
//
