ID H9G8K0_ANOCA Unreviewed; 3012 AA.
AC H9G8K0;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Dmx like 1 {ECO:0000313|Ensembl:ENSACAP00000004036.3};
GN Name=DMXL1 {ECO:0000313|Ensembl:ENSACAP00000004036.3};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000004036.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000004036.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000004036.3};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000004036.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_003223082.2; XM_003223034.3.
DR STRING; 28377.ENSACAP00000004036; -.
DR Ensembl; ENSACAT00000004128.4; ENSACAP00000004036.3; ENSACAG00000004113.4.
DR GeneID; 100563739; -.
DR KEGG; acs:100563739; -.
DR CTD; 1657; -.
DR eggNOG; KOG1064; Eukaryota.
DR GeneTree; ENSGT00390000000096; -.
DR HOGENOM; CLU_000267_0_0_1; -.
DR InParanoid; H9G8K0; -.
DR OrthoDB; 5480252at2759; -.
DR TreeFam; TF312896; -.
DR Proteomes; UP000001646; Unplaced.
DR Bgee; ENSACAG00000004113; Expressed in forelimb bud and 13 other cell types or tissues.
DR GO; GO:0043291; C:RAVE complex; IBA:GO_Central.
DR GO; GO:0007035; P:vacuolar acidification; IBA:GO_Central.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR022033; Rav1p_C.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13950:SF12; DMX-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR13950; RABCONNECTIN-RELATED; 1.
DR Pfam; PF12234; Rav1p_C; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM00320; WD40; 10.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 1448..1853
FT /note="RAVE complex protein Rav1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12234"
FT REPEAT 2909..2950
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 419..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1866..1887
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1909..1931
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2339..2388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2413..2439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 428..457
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2352..2367
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2368..2384
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2422..2436
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3012 AA; 336992 MW; 36B5664689FBB4B9 CRC64;
MNLHQVLTGA VNPGDHCFSV GNVGGHPFTA YASGCDVVIL GTDFERLQII PGAKHGNIQV
GCINCSMQQG KIAASYGNVI CIFEPIPHLK QKNIQHTGLH YQWQKSDQIS LENVVHNLTW
DPTGSRLLTG SNCLQLWSNT NFDTLLEEEN PEKADSQNWR VIWQCKTASE VYLMKFSPDG
EFFATAGKDD CLVKVWYNTD SWKAAVIPHA RTPETTVQEV AFSFIYLVHP RSVNDFSWRK
TSNYMPRGAV CNVLLTCCKD NICRLWAETL LPNDSLLYEG GYNHCPEPVK LTNNFKRNAS
SKESMKNALE LNLRPFRRGR RRSLALAHTG YLPHQQDPHE VHRNTPLQSN ALCHFHIAAS
INPATDIPLL PSIMSLSLNE NEEKHGPFVV HWLNNKELHF TLSMEVFLQQ LKKSFEHISS
EASTEESNQM DLKSDEETDD SRQNQKGNQE QRELTEEKPV SNSSYVPLSP AAIDHEIEIQ
LSEWNKNADM LFSIHPMDGS LLVWHVDWLD EYQPGMFRQV QVSFVSRIPV AFPTGDANSL
CRSIVMYACT KNVELALQQG KQKPSSLGRS CSMLISSGHS KSSNSLKLSI FTPNVMMISK
HADGSLNQWL VSFAEESAFS VVLSISHKSR YCGHRFHLND LACHSVLPLL LTTSHHNAIK
TPVLHGTKET PSTFHSKDNA NTTHDLNTVY SELILWRVDP VGPLSFSGGV SELARINSLH
VSAFSNVAWL PTLIPSYCLG AYCNSPSACF VASDGQHLRL YQAIIDARKL LCELSNPGIS
KYVGEVFNII SQQSTARPGC IVELDAITKL HGGKMQLLHV FQEDFILNNH ENRLSEKKTM
LPDSGYQKNG FSEKFYLILL EYTQNCTVLH MWKLHLKSIP VSVEEKIEPK EPEAVLQEEL
YSSSPDQEKT QCSLTKKYQA CKENLQSTSQ LALSSEIVYS KRLNLPEGVE IISIKPSAGH
LSSSSIYPVC RAPYLLATLC SDGKVRFWRC TVAPESDVAS ELECPTNSDI YVWEEWPLLI
EDGLLSSSAL NIPGLPLEIS CAHTNRLAVA YKRTPPKNSR CSQDFLVNVA IFECESTGGA
SWILEQTLHL DELNPTMDCL DIDCSFSSNR NENLTSRTKY LVHLDWMSRE DGSHILTVGI
GSKLHMFGQL AGKIQEQSGK EMFVLPVWEN AKTSCASRFI LLRCVDLVSS VESSPPLPVS
LSWVRDGILV VGMDCEMHVY SQWQPLSKQE SVAGDSYSGS TPSIISLIKQ GQSPGVHPPK
RALTRSMTSL AQKLSGKRTA YDLSLEMEDS GLFEAAHSLC PTLPQYHPLQ LLELMDLGKV
RRAKAILSHL VKCIAGEVIV VNDPDHEKRC RSLSICASGS STRDPMTFSR GVITDYTEID
SVPPLPLYAL LAADEECPYA CTEKPNNQRN LKKHDLPAEN YEDLFQNSSL HTDDLTMFEE
EEEDKKPAVI DLSQYSPTYF GPEHAQVLSR HLLHSSLPGL TRIEQMSLMA LADTIAITST
DIGESRDRSK GGETLDECGL KFLLAVRLHT FMTTSLPPAH RAQLLHQGLS SSHFAWAFHS
VAEEELLNVL PAMQKHDPTW SELRAMGVGW WVRNTHNLRR CIEKVAKAAF QRNNDPLDAA
IFYIAMKKKA VIWGLYRSIK DTKMTQFFGQ NFTEDRWRKA ALKNAFSLLG KQRFEHSAAF
FLLAGHLKDA VEVCLEKLHD IQLALVIARL YEPEFEISGT YKSILQKKIL WNKSHSTESP
SNAHGDPFLR SMAYWILENY SHALDTLISQ PVLDEEDDGR ISSCSASVFN FYNYLRTHPL
LLRRHFGSSD LSSTRICVTG ENALADEINL AERRLFFTTA YAHLKAGCPM LALEVLSKMP
KVVKKSKPLE RTPSLRDTSK GCSPCSPVLM ETKDDKSFSI DWSQPVINGL ESSSDGSSDK
QSSSGLFDWS QPSTVFQDEP LELKWDSDKD EDSEDACLVM KPVQKTVSEK PNEVSSSYTE
TYSSGNENNV LTLSEDIISA QLKFRACLKI LTMELRTLST GYEVDGGKLR YQLYHWLERE
VVALQNTCDY SVEAEDVQSR ISRVNGEALL SEVTDEFSDT QQNILSQRRQ WLIKYQSLLR
MFLSYCILHG SHGGGLASVR MELILLLQES QQELTAQLPL NAVSEQNSIP LLFACTASAK
TVVANPLLHL GNLTHDILHA IVDLDSPPHP DIQNTKIHVM HTLAASLSAC IYQSLCGSHN
YSSLQANQFT GTVYQTLLLS HRHSLRTASS DETITPNTTP AQWPGVLALI QLLNSAGEDV
QSGITILLCE ILTAVYLSLF IHGLATHSSN ELYRIVAHPL NDKMWFAVFG GGAKIPKKGQ
IQQTTKMASS PVDESEKQHK RFRLSSKSSS KESSQTTVPS VEQDTPNYKE KFIPPELSIW
DYFIAKPFLP SSQTKSEYDS EESQESSDED DDGGFSLDLT LQEHSNSNSY SWSLMRLAMV
QLVLHNLKTF YPLAGHDLSE LPVSSPLCHA VLKILQRWEQ VLLRRLEMHG SPPENFISVH
TSQDVAASGP ALLRHKALLE PTNTPFKSKS HHALSVKRLW QYLIKQEMVQ ETFIRNIFTK
KRCLNESLED QSEHIKSTSM EDNGINKIET DMGYPGNKAR IIHKESDIIT AFAVNKANRN
CIAIASSHDI QELDVSGILA TQFYTWVDDE EVEAKGADDF LVIHARDDLG NIQGTTPYTH
SNPGTPINMP WLGSTQTGRG AAVMIKKPIN NVRRMASHPT LPYYLTGAQD GSVRMFEWGH
SQQITCFRSG GNSRVTRMRF NYQGNKFGIV DGDGHISLYQ TNWKSCLHNG NTPKPYLTWQ
CHNKTASDFV FVSSSSLIAT AGQSTDNRNI CLWDTLVAPT SSLVHAFTCH DTGATVLAYA
PKHQLLISGG RKGYTCLIDL RQKQQRQFFQ SHDSPVKAIA VDPTEEYFVT GSAEGNIKVW
SLSNFSLLHT FINEHSRQSI FRNLGTGVMQ IETGPANHIF SCGADGTVKM RILPDRFNSF
SDMLKTDVKL ML
//
