ID H9GAD0_ANOCA Unreviewed; 583 AA.
AC H9GAD0;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=BTB domain-containing protein {ECO:0000259|PROSITE:PS50097};
GN Name=klhl18 {ECO:0000313|Ensembl:ENSACAP00000005467.4};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000005467.4, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000005467.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000005467.4};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000005467.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR RefSeq; XP_003229329.1; XM_003229281.3.
DR AlphaFoldDB; H9GAD0; -.
DR STRING; 28377.ENSACAP00000005467; -.
DR Ensembl; ENSACAT00000005586.4; ENSACAP00000005467.4; ENSACAG00000005482.4.
DR GeneID; 100563113; -.
DR KEGG; acs:100563113; -.
DR CTD; 23276; -.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000157026; -.
DR HOGENOM; CLU_004253_14_2_1; -.
DR InParanoid; H9GAD0; -.
DR OrthoDB; 5472491at2759; -.
DR TreeFam; TF329218; -.
DR Proteomes; UP000001646; Unplaced.
DR Bgee; ENSACAG00000005482; Expressed in ovary and 11 other cell types or tissues.
DR CDD; cd18457; BACK_KLHL18; 1.
DR CDD; cd18247; BTB_POZ_KLHL18; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR030603; KLHL18_BTB/POZ.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412:SF35; ACTIN-BINDING PROTEIN IPP; 1.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 6.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR PRINTS; PR00501; KELCHREPEAT.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF50965; Galactose oxidase, central domain; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 42..109
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 583 AA; 64682 MW; 3358234BAF3C0454 CRC64;
MLETAGPDPE LDPEDLVHFS VGDLPSRGYG VMGEIRRQGK LCDVTLKVGD HKFSAHRIVL
AASIPYFHAM FTNDMMECKQ DEIVMQGMDP SALEALINFA YNGHLAIDQQ NVQSLLMGAS
FLQLQNIKDA CCSFLRERLH PKNCLGVRQF AETMMCAVLY DAANSFIHQH FVEVSMSEEF
LALSFEDVLE LVSRDELNVK LEEQVFEAAL AWVRYDREHR EPFLPELLSK IRLPLCRPQF
LTDRVQQDDL VRSCHKCRDL VDEAKDYHLM PERQPHLSAF KTRPRCCTSI AGLIYAVGGL
NSAANFYAGD SLNVVEVFDP VANHWEKCQP MTTARSRVGV AVLNGLLYAI GGYDGQLRLS
TVEVYNPEAD SWSKVGSMNS KRSAMGTVVL DGQIYVCGGY DGTSSLNSVE AYSPETDRWT
VVTPMSSNRS AAGVTVFEGR IFVSGGHDGL QIFNSVEHYN PHTASWHPVA SMLNKRCRHG
AAALGSKMYV CGGYDGCGFL SIAEVYDSMS DQWYLIVPMN TRRSRVSLVA NCGRLYAVGG
YDGQSNLSSV EMYDPDTNRW TFMAPMVCHE GGVGVGCIPL LAI
//
