ID   H9GFM3_ANOCA            Unreviewed;       750 AA.
AC   H9GFM3;
DT   16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT   16-MAY-2012, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   SubName: Full=Pleckstrin homology domain containing M3 {ECO:0000313|Ensembl:ENSACAP00000009605.2};
GN   Name=PLEKHM3 {ECO:0000313|Ensembl:ENSACAP00000009605.2};
OS   Anolis carolinensis (Green anole) (American chameleon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Iguania; Dactyloidae; Anolis.
OX   NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000009605.2, ECO:0000313|Proteomes:UP000001646};
RN   [1] {ECO:0000313|Ensembl:ENSACAP00000009605.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000009605.2};
RG   The Genome Sequencing Platform;
RA   Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA   Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACAP00000009605.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_003226125.1; XM_003226077.2.
DR   RefSeq; XP_016852139.1; XM_016996650.1.
DR   AlphaFoldDB; H9GFM3; -.
DR   STRING; 28377.ENSACAP00000009605; -.
DR   Ensembl; ENSACAT00000009802.3; ENSACAP00000009605.2; ENSACAG00000009797.3.
DR   GeneID; 100555030; -.
DR   KEGG; acs:100555030; -.
DR   CTD; 389072; -.
DR   eggNOG; KOG1829; Eukaryota.
DR   GeneTree; ENSGT00940000159743; -.
DR   HOGENOM; CLU_021585_0_0_1; -.
DR   InParanoid; H9GFM3; -.
DR   OMA; CELCHNG; -.
DR   OrthoDB; 126314at2759; -.
DR   TreeFam; TF317067; -.
DR   Proteomes; UP000001646; Unplaced.
DR   Bgee; ENSACAG00000009797; Expressed in testis and 13 other cell types or tissues.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045445; P:myoblast differentiation; IEA:Ensembl.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR025258; RH_dom.
DR   PANTHER; PTHR12326; PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR12326:SF10; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 3; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF13901; RH_dom; 1.
DR   SMART; SM01175; DUF4206; 1.
DR   SMART; SM00233; PH; 2.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          351..446
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
SQ   SEQUENCE   750 AA;  85937 MW;  4C7CF4485DAB3A33 CRC64;
     MEALEVDDIS PALEVTEDFF NTFDAKLDNV QPSEVYGIQE VPELVGHEVF NSCGDLRNVV
     SLGQNNLVWE HCKNGLSETK VQTAFPAKEQ FRVQRGTVPD NLSWMEQREA STFNILNICR
     RRVRPRSVND ITMQSEEAAT FKPGHNRSRS DITRIDWSII LNSAPPQQVS NHGNRCPKVS
     FTPAGFKKGK DVQGNSEHKP TFSNTLKKGY LEIKRNHDSY WQACYAELSP YELYLFWLDS
     SGNQTLPTVY LLLHFQSITV ETSVVDAVLF NNSHLQLKAE SPWEALDWGQ KLREAVHSSV
     PSFLRPQGDL RNSHKLDNEE NNIAPNHILQ KEPAEFFQST SVTENIKDYQ NILKSGTLYR
     LTLQNNWKAF HFVLSPSLLM AFQIGGPDED PLWSYNTEVC LSVQTDILDD CDSCFQVIFP
     QDVLRLRAET RQRAQEWMEA LKAATSTASL GQNVQVTLRN KVQNLSCRKD HQKIKRQSVT
     TSFLSILTTL SLERGLTAQS FKCAGCQRAI GLSNGKAKVC SYSGWYYCSF CHVDDNFLIP
     ARLVHNWDTS KYKVSKQAKE FLEYVYEEPL IDIQQENPML YRHVEPLATV VRLRQQLKSL
     RAYLFSCRAT VAEDLRRRIF PREYLLQQIH LYSLADLQQV IEGKLAPFLG KVIKFATSHV
     YSCSLCSQKG FICEICNNGE ILYPFEDIST SRCESCGAVF HSECKVKAVP CPRCVRRELQ
     MKQKSFWRRL NMDESLEEAC NMFELSYQNT
//