ID H9GH60_ANOCA Unreviewed; 372 AA.
AC H9GH60;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000010872.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000010872.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000010872.3};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000010872.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H9GH60; -.
DR STRING; 28377.ENSACAP00000010872; -.
DR Ensembl; ENSACAT00000011098.3; ENSACAP00000010872.3; ENSACAG00000011072.3.
DR eggNOG; KOG2113; Eukaryota.
DR GeneTree; ENSGT00940000160013; -.
DR HOGENOM; CLU_025598_2_0_1; -.
DR InParanoid; H9GH60; -.
DR TreeFam; TF315107; -.
DR Proteomes; UP000001646; Unplaced.
DR Bgee; ENSACAG00000011072; Expressed in hemipenis and 8 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22424; KH-I_MEX3_rpt2; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047226; KH-I_MEX3_rpt2.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR047227; MEX3.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23285; RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR23285:SF5; RNA-BINDING PROTEIN MEX3B; 1.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00322; KH; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00117}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 321..361
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 164..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 223..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 372 AA; 39032 MW; C5150E91E6B2F3E1 CRC64;
PVRGEEPLFV VTGRKEDVAM ARREIISAAE HFSLIRASRH KSAALNGASA AAPAPPHLPG
QTTIQVRVPY RVVGLVVGPK GATIKRIQQQ THTYIVTPSR DKEPVFEVTG MPENVDRARE
EIEAHIALRT GAGGVGGAGG LVELPDDNDF HANGTDVGFE MSGSLWSKPT IPPTPGRKPF
GTLRHDSSSS LGSASTDSFH RLADFSPPSP ALSFTHHNGN GYGAYGGAEG LPSPDVPPSG
GQRRGVGPPP TRVSPPLHVA LPAEQPQQHP LARRVRSDPG GRCPLSGLPS DSSASSSSSS
SSSSSSSCSS SGLRRKGSRE CAVCFESEVI AALVPCGHNL FCLECANRIC ERSQPQCPVC
HSAVTQAIRI FS
//
