ID H9GUJ8_ANOCA Unreviewed; 1228 AA.
AC H9GUJ8;
DT 16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=TFIIS central domain-containing protein {ECO:0000259|PROSITE:PS51321};
GN Name=spocd1 {ECO:0000313|Ensembl:ENSACAP00000020749.3};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000020749.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000020749.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000020749.3};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000020749.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H9GUJ8; -.
DR STRING; 28377.ENSACAP00000020749; -.
DR Ensembl; ENSACAT00000025899.3; ENSACAP00000020749.3; ENSACAG00000011847.4.
DR eggNOG; KOG1634; Eukaryota.
DR GeneTree; ENSGT00940000162194; -.
DR HOGENOM; CLU_503965_0_0_1; -.
DR TreeFam; TF343963; -.
DR Proteomes; UP000001646; Unplaced.
DR Bgee; ENSACAG00000011847; Expressed in ovary and 2 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0006351; P:DNA-templated transcription; IBA:GO_Central.
DR Gene3D; 1.10.472.30; Transcription elongation factor S-II, central domain; 1.
DR InterPro; IPR012921; SPOC_C.
DR InterPro; IPR003618; TFIIS_cen_dom.
DR InterPro; IPR036575; TFIIS_cen_dom_sf.
DR PANTHER; PTHR11477:SF18; SPOC DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR11477; TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07744; SPOC; 1.
DR Pfam; PF07500; TFIIS_M; 1.
DR SMART; SM00510; TFS2M; 1.
DR SUPFAM; SSF46942; Elongation factor TFIIS domain 2; 1.
DR PROSITE; PS51321; TFIIS_CENTRAL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001646}.
FT DOMAIN 621..741
FT /note="TFIIS central"
FT /evidence="ECO:0000259|PROSITE:PS51321"
FT REGION 23..165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 223..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 417..620
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 722..787
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 974..1032
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..69
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..112
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..156
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..264
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 266..280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..304
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..442
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 500..515
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..535
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..620
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..754
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 760..787
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 989..1008
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1228 AA; 134595 MW; 7A6148D94055D0EA CRC64;
MEKSTTYKLD DLNKGLELVL NIDDESRHKK LQDPDGHGDI REPRKGRLKK EGSVTQKDHR
VHSRSPVLDG KGSEGDVFSR FAQNGQAAEK GMSDNDYISE KGPYEEQRAF PFKPDGEQGS
KQESILSEED FSTGLDGKIQ GTSKRKSGEK TFSKPEHLSK SSLSTGIKEC ATMKPCYVLL
EDMYHGEKAK DIHYLKALNA KERPPKARID KGDVLKKLRS ALHNVLDKSS PKNSQKPLQI
RNDDKPLEKG KRDELQRDSE LKSLVKRLNS GGSETVGGNM ELNSPGKVRH SGRSDTDHSA
EKQGCRISSP DITAICEQGV FARFSFTDPD DDNSVIDLCD IQEDVKVIER KQGDPARVSE
ASKLKATSFK PPKMFIDYGN KMVKQALGEQ TSHKGGKFPK GPHSVFSKEA LREDVGQPSG
INVFPASHRK TSHTSKTDSS CSAKKLVGKA KFPNVAPKRT SASRLSDKAT SEEGHQVSCG
SRPHVPLHLG HKSGLKDMSP RRTKTTASSG KRTVPDRNAS NEDRTEVEEP ETELSGSRVK
LLGSPIASRD NFHSGRVIEV EDSSNSEGSQ GSFVTISPGR RNERQLDSAN KGLNLEDSNA
KKRSQGLNVS TAPAQLSEKQ SRSKVVDALN ETLQKRLEAS PEVTLPGKDV SRIARQVERE
LFRLSCSVDH HYRSKYRSLL FNLRSPENQP LFQKVVLGEI TPKRLVQMTS LELAPKELAE
WRVKESKRKE TPPSQGKIIS KRPTELRRDA GEPSDGFRSP ASTGKVTADC NARQKPPSNK
RSFSQKTKPI FSEGEGKALQ EDSPVPALFP KKQRVEEPSW IGFIRMFSIK QFWAKAYPVS
GPSDQLCQGL PHYLQSKGCI VPEDVWAYLD AIWPAKSKEM GVIRFQPSLS RDSSLYNMLY
TYLNNKQRYG VVENPGMEVF VVPLAAYQPV PSKLRPLGGP GLDPSHPSLL LGLLLPKRTS
QSALETMVSL SPNPKKKVVR FSDSPQTRCS APPSPPPPPP PPPRLPKGGP VSWKENQVPP
VFPRGDPSPQ ETLLGFTEEF CRDVFQRDPQ CFNPEGPGDG APPAAFEEPP WIGPPCPAGD
QVPLCVDSDP SQIWNMLGLL MGPEQHGTCG VPAPEFFSDP LFTGVMSPCN APLVPPPALN
PGSVAGESGS LLEGTLSLMD QLQTCLQSQE PQPAAFGLPA VPPEITSTFS QAAVGLDFPL
VQGEDGTFAH LQQLLATLSG QIPPPSAL
//
