GenomeNet

Database: UniProt
Entry: H9IYU7_BOMMO
LinkDB: H9IYU7_BOMMO
Original site: H9IYU7_BOMMO 
ID   H9IYU7_BOMMO            Unreviewed;       836 AA.
AC   H9IYU7;
DT   16-MAY-2012, integrated into UniProtKB/TrEMBL.
DT   16-MAY-2012, sequence version 1.
DT   27-SEP-2017, entry version 23.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
OS   Bombyx mori (Silk moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Lepidoptera; Glossata; Ditrysia;
OC   Bombycoidea; Bombycidae; Bombycinae; Bombyx.
OX   NCBI_TaxID=7091 {ECO:0000313|EnsemblMetazoa:BGIBMGA002432-TA, ECO:0000313|Proteomes:UP000005204};
RN   [1] {ECO:0000313|EnsemblMetazoa:BGIBMGA002432-TA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=p50T {ECO:0000313|EnsemblMetazoa:BGIBMGA002432-TA};
RX   PubMed=19121390; DOI=10.1016/j.ibmb.2008.11.004;
RG   International Silkworm Genome Consortium;
RT   "The genome of a lepidopteran model insect, the silkworm Bombyx
RT   mori.";
RL   Insect Biochem. Mol. Biol. 38:1036-1045(2008).
RN   [2] {ECO:0000313|EnsemblMetazoa:BGIBMGA002432-TA}
RP   IDENTIFICATION.
RC   STRAIN=p50T (Dazao) {ECO:0000313|EnsemblMetazoa:BGIBMGA002432-TA};
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; BABH01010757; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BABH01010758; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BABH01010759; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 7091.BGIBMGA002432-TA; -.
DR   EnsemblMetazoa; BGIBMGA002432-RA; BGIBMGA002432-TA; BGIBMGA002432.
DR   eggNOG; KOG2189; Eukaryota.
DR   eggNOG; COG1269; LUCA.
DR   InParanoid; H9IYU7; -.
DR   OMA; FILRANH; -.
DR   Proteomes; UP000005204; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005204};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005204};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    391    418       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    438    463       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    531    552       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    564    584       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    596    616       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    636    654       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    772    790       Helical. {ECO:0000256|RuleBase:RU361189}.
SQ   SEQUENCE   836 AA;  95492 MW;  7DF422B56A16244C CRC64;
     MGAMFRSEEM ALCQLFIQPE AAYTSVSELG EAGSVQFRDL NPDVNAFQRK FVNEVRRCDE
     MERKLRYIEA EVHKDGVHIP AVKEAPRAPN PREIIDLEAK KTENEILELS HNAVNLKQNY
     LELTELRHVL EKTEAFFTAQ EEIGMDSLTK SLISDETGQQ AATRGRLGFV AGVVQRERVP
     AFERMLWRIS RGNVFLRRAE LDKPLEDPAT GNEIYKTVFV AFFQGEQLKS RIKKVCTGFH
     ASLYPCPPSN TERQDMVKGV RTRLEDLNMV LNQTRDHRQR VLASVAKELT SWTIMVRKMK
     AIYHTLNLFN MDVTKKCLIG ECWVPTADLP NVQKALADGS NACGSSIPSF LNCIETDEEP
     PTFNRTNKFT RGFQNLIDAY GVASYRECNP ALYTIITFPF LFAVMFGDLG HGCIMAMFGG
     WMVVKEVSLA AKKSNNEIWN IFFAGRYIIL LMGCFSMYTG LVYNDIFSKS LNIFGSSWHI
     PYDNHTLAEN GALTLDPKDA YTEVPYFIGI DPIWQSADNK IIFLNSYKMK LSIIFGVIHM
     IFGVCMSVVN YNFFKRRYSI FLEFLPQIVF LALLFLYMVF MMFFKWIAYS TKNDELAYTQ
     GCAPSVLILF INMMLFSKNV PEEGCKEFMF DAQSDIQRVF VFIALLCIPV MLLGKPLYLL
     ATKKNNPKPE HSNGSVNQGI ELQEQTDLGD VQPKPEAKSS GGHDHEDEPF SEIMIHQAIH
     TIEYVLSTIS HTASYLRLWA LSLAHAELSE VLWNMVLTFG LKDHNYVGAI KLYVAFCFWA
     LFTLAILVMM EGLSAFLHTL RLHWVEFMSK FYAGLGYIFQ PFCFKTILEQ EENKDD
//
DBGET integrated database retrieval system