ID H9XR70_HBV Unreviewed; 356 AA.
AC H9XR70;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 14-DEC-2022, entry version 28.
DE SubName: Full=Polymerase {ECO:0000313|EMBL:AFH01907.1};
DE Flags: Fragment;
GN Name=P {ECO:0000313|EMBL:AFH01907.1};
OS Hepatitis B virus (HBV).
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Blubervirales; Hepadnaviridae; Orthohepadnavirus.
OX NCBI_TaxID=10407 {ECO:0000313|EMBL:AFH01907.1};
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9598; Pan troglodytes (Chimpanzee).
RN [1] {ECO:0000313|EMBL:AFH01907.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=08/IVVI/3581 {ECO:0000313|EMBL:AFH01907.1};
RA Dunford L.M., Carr M.J., Nguyen L.A.T., Hall W.W.;
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFH01907.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=08/IVVI/3581 {ECO:0000313|EMBL:AFH01907.1};
RX PubMed=22720022; DOI=10.1371/journal.pone.0039027;
RA Dunford L., Carr M.J., Dean J., Nguyen L.T., Ta Thi T.H., Nguyen B.T.,
RA Connell J., Coughlan S., Nguyen H.T., Hall W.W., Thi L.A.;
RT "A multicentre molecular analysis of hepatitis B and blood-borne virus
RT coinfections in viet nam.";
RL PLoS ONE 7:E39027-E39027(2012).
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DR EMBL; JQ281190; AFH01907.1; -; Genomic_DNA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR000201; DNApol_viral_N.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR Pfam; PF00242; DNA_pol_viral_N; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 96..339
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT REGION 26..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFH01907.1"
FT NON_TER 356
FT /evidence="ECO:0000313|EMBL:AFH01907.1"
SQ SEQUENCE 356 AA; 39673 MW; 7C13EA7F5A37AA39 CRC64;
SGHTHNCASS ASSCLHQSAV RKAAYSHIST SKGHSSSGHA VELHHFPSNS SRSQSQGSVL
SCWWLQFRNS EPCSEYCLGH IVNLLEDWGP CTEHGEHRIR TPRTPARVTG GVFLVDKNPH
NTTESRLVVD FSQFSRGNTR VSWPKFAVPN LQSLTNLLSS NLSWLSLDVS AAFYHLPLHP
AAMPHLLVGS SGLSRYVARL SSTSRIINHQ HRTMQNLHDS CSRNLYVSLM LLYKTYGRKL
HLYSHPIILG FRKIPMGVGL SPFLLAQFTS AVCSVVRRAF PHCLAFSYMD DVVLGAKSVQ
HLESLYAAVT HFLVSLGIHV NPHKTKRWGY SLNFMGYVIG SWGSLPQEHI VQKIKL
//
