ID H9ZEN0_MACMU Unreviewed; 1860 AA.
AC H9ZEN0;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Protein TANC1 isoform 1 {ECO:0000313|EMBL:AFH34396.1};
GN Name=TANC1 {ECO:0000313|EMBL:AFH34396.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:AFH34396.1};
RN [1] {ECO:0000313|EMBL:AFH34396.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Thymus {ECO:0000313|EMBL:AFH34396.1};
RX PubMed=25319552; DOI=10.1186/1745-6150-9-20;
RA Zimin A.V., Cornish A.S., Maudhoo M.D., Gibbs R.M., Zhang X., Pandey S.,
RA Meehan D.T., Wipfler K., Bosinger S.E., Johnson Z.P., Tharp G.K.,
RA Marcais G., Roberts M., Ferguson B., Fox H.S., Treangen T., Salzberg S.L.,
RA Yorke J.A., Norgren R.B.Jr.;
RT "A new rhesus macaque assembly and annotation for next-generation
RT sequencing analyses.";
RL Biol. Direct 9:20-20(2014).
CC -!- SIMILARITY: Belongs to the TANC family.
CC {ECO:0000256|ARBA:ARBA00038259}.
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DR EMBL; JU477592; AFH34396.1; -; mRNA.
DR GO; GO:0045202; C:synapse; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR24166:SF23; PROTEIN TANC1; 1.
DR PANTHER; PTHR24166; ROLLING PEBBLES, ISOFORM B; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF13637; Ank_4; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 10.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 6.
DR PROSITE; PS50088; ANK_REPEAT; 6.
DR PROSITE; PS50005; TPR; 2.
PE 2: Evidence at transcript level;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Synapse {ECO:0000256|ARBA:ARBA00023018};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 967..999
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1078..1110
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1111..1143
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1144..1176
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1177..1209
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1210..1242
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1289..1322
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1336..1369
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 62..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 257..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 439..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1420..1567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1592..1701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..127
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..287
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..311
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 439..455
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..485
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1446..1460
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1468..1503
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1525..1559
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1607..1633
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1645..1693
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1860 AA; 201908 MW; 458DBF2626019427 CRC64;
MLKAVLKKSR EGGKGGKKEA GGDFGPETSP VLPLDHGADS PVSSLPAAED TYRVSLAKGV
SMSLPSSPLL PRQSHLVQSR ANKKSPGPVR KPKYVESPRV PGDAVIMPFR EVSKPTEPDE
HEAKADNEPS CSPAAQELLT RLGFLLGEGI PSATHITIED KNETMCTALS QGISPCSTLT
SSTASPSTDS PCSTLNSCVS KTAANKSPCE TISSPSSTLE SKDSGIIATI TSSSENDDRS
GSSLEWNKDG SLRLGVQKGV LHDRRADNCS PVAEEETTGS AESTLPKAES SAGDGPVPYS
QGSSSLIMPR PNSVAATSST KLEDLSYLDG QRNAPLRTSI RLPWHNTAGG RAQEVKARFA
PYKPQDILLK PLLFEVPSIT TDSVFVGRDW LFHQIEENLR NTELAENRGA VVVGNVGFGK
TAIISKLVAL SCHGSRMRQI ASNSPSSSPK TSDPAQDLHF TPLFSPSSST SASSTAKTPL
GSVSAENQRP REDAVKYLAS KVVAYHYCQA DNTYTCLVPE FVHSIAALLC RSHQLAAYRD
LLIKEPQLQS MLSLRSCVQD PVAAFKRGVL EPLTNLRNEQ KIPEEEYIIL IDGLNEAEFH
KPDYGDTLSS FITKIISKFP AWLKLIVTVR ANFQEIISAL PFVKLSLDDF PDNKDIHSDL
HAYVQHRVHS SQDILSNISL NGKADATLIG KVSSHLVLRS LGSYLYLKLT LDLFQRGHLV
IKSASYKVVP VSLSELYLLQ CNMKFMTQSA FERALPILNV ALASLHPMTD EQIFQAINAG
HIQGEQGWED FQQRMDALSC FLIKRRDKTR MFCHPSFREW LVWRADGENT AFLCEPRNGH
ALLAFMFSRQ EGKLNRQQTM ELGHHILKAH IFKGLSKKTG ISSSHLQALW IGYSTEGLSA
ALASLRNLYT PNVKVSRLLI LGGANVNYRT EVLNNAPILC VQSHLGHEEV VTLLLEFGAC
LDGTSENGMT ALCYAAAAGH MKLVCLLTKK GARVDHLDKK GQCALVHSAL RGHGDILQYL
LTCEWSPGPP QPGALRKNHA LQQALTAAAS MGHSSVVQCL LGMEKEHEVE VNGTDTLWGE
TALTAAAGRG KLEVCELLLG RGAAVSRTNR RGVPPLFCAA RQGHWQIVRL LLERGCDVNL
SDKQGRTPLM VAACEGHLST VEFLLSKGAA LSSLDKEGLS ALSWACLKGH RAVVQYLVEE
GAAIDQMDKN GRTPLDLAAF YGDAETVLYL VEKGAVIEHV DHSGMRPLDR AIGCRNTSVV
VALLRKGAKL GNAAWAMATS KPDILIILLQ KLMEEGNVMY KKGKMKEAAQ RYQYALRKFP
REGFGEDMRP FNELRVSLYL NLSRCRRKTN DFGMAEEFAS KALEMKPKSY EAFYARARAK
RNSRQFVAAL ADLQEAVKLC PTNQEIKRLL ARVEEECKQL QRSQQQKQQG LPPAPPNDSE
NEEDAPTPGL SDHFHPEETE EEETSPQEES VSPTPRSQPS SSVPSPYIRN LQEGLQSKGR
PVSPQSRAGI GKPLREPVAQ PGLVLQPSKQ AQIVKTSQHL GSGQSALRNG STKVQISSQN
PPPSPMPGRI AATPAGSRTQ HLEGTGTFTT GAGCGHFGDR LGPSQNVRLQ RGESGSAHPL
PNKTKTTERL LSHSSMPVDA APPNQGGLAT SSDMRHPASL TSSGSSGSPS SSIKMSSSTS
SLTSSSSFSD GFKVQGPDTR IKDKVVTHVQ GGTAEHRPRN TPFMGIMDKT ARFQQQSNPP
SRAWHCPAPE RLLANTSAAG LQSAATEKPS LVQAGGCNNQ AKTCSVSTLS ASVHNGAQVK
ELEENKCQIP VHCQENRITK TVSHLYQESI SKQQPHISNE AHRSHLTAAK PKRSFIESNV
//
