ID I0EGK7_HELPX Unreviewed; 550 AA.
AC I0EGK7;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Cell division protein (FtsH) {ECO:0000313|EMBL:AFI02076.1};
GN ORFNames=HPPC18_01430 {ECO:0000313|EMBL:AFI02076.1};
OS Helicobacter pylori PeCan18.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1163742 {ECO:0000313|EMBL:AFI02076.1, ECO:0000313|Proteomes:UP000005006};
RN [1] {ECO:0000313|EMBL:AFI02076.1, ECO:0000313|Proteomes:UP000005006}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PeCan18 {ECO:0000313|EMBL:AFI02076.1,
RC ECO:0000313|Proteomes:UP000005006};
RA Kersulyte D., Ramirez Ramos A., Recarvarren S., Barua R.L., Watanabe J.,
RA Gilman R.H., Berg D.E.;
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|RuleBase:RU003651}.
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DR EMBL; CP003475; AFI02076.1; -; Genomic_DNA.
DR RefSeq; WP_001116702.1; NC_017742.1.
DR AlphaFoldDB; I0EGK7; -.
DR KEGG; hca:HPPC18_01430; -.
DR PATRIC; fig|1163742.3.peg.294; -.
DR HOGENOM; CLU_000688_16_2_7; -.
DR Proteomes; UP000005006; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd19501; RecA-like_FtsH; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.58.760; Peptidase M41; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR037219; Peptidase_M41-like.
DR PANTHER; PTHR23076:SF97; ATP-DEPENDENT ZINC METALLOPROTEASE FTSH 2, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR23076; METALLOPROTEASE M41 FTSH; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF140990; FtsH protease domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU003651};
KW Cell cycle {ECO:0000313|EMBL:AFI02076.1};
KW Cell division {ECO:0000313|EMBL:AFI02076.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 194..330
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 550 AA; 62887 MW; 3221B290C70F1882 CRC64;
MPFSKNLENL TAPFKHIKNR SLILALGFLI LTFCLLLFLV LSDVSRLISG KDFFYVIQSH
PKQTLTEDEN YFYANKGLYK TNKEAFLRVY KIPESMPIEK RESLNKVSKI FLALLFFISS
MLFGIFWRLP KRLDTKMSLE SAHKNELENA FQRYDALGVR FEDIAGVDEV KEELLEVIDY
LKNPKKYQDL GIFLPKGILL VGPPGVGKTM IAKALASEAK VPFFYESGSA FSQIYVGAGA
KKVHELFMHA KRHAPSIIFI DEIDALGKAR GGHRSDEREA TLNQLLTEMD GFLQNDEVVV
IGATNQMEVM DEALLRSKRF DRRIFISLPD LLERQSILEK LLENKKHVLD YLKIAKICVG
FSGAMLATLI NESALNALKH QREEITESDI LEVKDKIAYG KKKPQTLDEN QKELVALYQS
AKALSAYWLE IEFDKAPLLG EFIAFNENKI HSESEIKNYI KVYLSGTIIL ELLYKERYSL
SKQDLQKAKF LNEFMASELL LTPTKESLSV LYEEQLEFLK PQIAACKRLS VLLLEQECLE
HANFYDLLSG
//
