ID I0FVU8_MACMU Unreviewed; 1147 AA.
AC I0FVU8;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 13-SEP-2023, entry version 45.
DE SubName: Full=Plakophilin-4 isoform b {ECO:0000313|EMBL:AFI38574.1};
GN Name=PKP4 {ECO:0000313|EMBL:AFI38574.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:AFI38574.1};
RN [1] {ECO:0000313|EMBL:AFI38574.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Orbital {ECO:0000313|EMBL:AFJ71765.1}, and Testis
RC {ECO:0000313|EMBL:AFI38574.1};
RX PubMed=25319552; DOI=10.1186/1745-6150-9-20;
RA Zimin A.V., Cornish A.S., Maudhoo M.D., Gibbs R.M., Zhang X., Pandey S.,
RA Meehan D.T., Wipfler K., Bosinger S.E., Johnson Z.P., Tharp G.K.,
RA Marcais G., Roberts M., Ferguson B., Fox H.S., Treangen T., Salzberg S.L.,
RA Yorke J.A., Norgren R.B.Jr.;
RT "A new rhesus macaque assembly and annotation for next-generation
RT sequencing analyses.";
RL Biol. Direct 9:20-20(2014).
CC -!- SIMILARITY: Belongs to the beta-catenin family.
CC {ECO:0000256|ARBA:ARBA00005462}.
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DR EMBL; JV048503; AFI38574.1; -; mRNA.
DR EMBL; JV636425; AFJ71765.1; -; mRNA.
DR RefSeq; XP_014965639.1; XM_015110153.1.
DR AlphaFoldDB; I0FVU8; -.
DR GO; GO:0098609; P:cell-cell adhesion; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR028435; Plakophilin/d_Catenin.
DR PANTHER; PTHR10372:SF8; PLAKOPHILIN-4; 1.
DR PANTHER; PTHR10372; PLAKOPHILLIN-RELATED; 1.
DR Pfam; PF00514; Arm; 3.
DR SMART; SM00185; ARM; 6.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 3.
PE 2: Evidence at transcript level;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889}.
FT REPEAT 568..595
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 612..655
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 870..907
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 119..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 209..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 288..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 771..808
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1022..1057
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 771..785
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1025..1057
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1147 AA; 127022 MW; 69FC04750AD5178E CRC64;
MPAPEQASLV EEGQPQTRQE AASTGPGMEP ETTATTILAS VKEQELQFQR LTRELEVERQ
IVASQLERCR LGAESPSIAS TSSTEKSFPW RAADVPNTGV SKPKVSDAVH PNNYLIRTEP
EQGTLYSPEQ TSLHERSLGN SRSSTQMNSY SDSGYQEAGS FHNSQNVSKA DNRQQHSFIG
STNNHVVRNS RAEGQTLVQP SVANRAMRRV SSVPSRAQSP SYVISTGVSP SRGSLRTSLG
SGFGSPSVTD PRPLNPSAYS STTLPAVRAA SPYSQRPASP TAIRRIGSVT SRQTSNPNGP
TPQYQTTARV GSPLTLTDAQ TRVASPSQGQ VGSSSPKRSG MTAVPQHLGP SLQRTVHDME
QFGQQQYDIY ERMVPPRPDS LTGLRSSYAS QHSQLGQDLR SAVSPDLHIT PIYEGRTYYS
PVYRSPNHGT VELQGSQTAL YRTGSVGIGN LQRTSSQRST LTYQRNNYAL NTTATYAEPY
RPIQYRVQEC NYNRLQHIVS ADDGTTRSPS IDSIQKDPRE FAWRDPELPE VIHMLQHQFP
SVQANAAAYL QHLCFGDNKV KMEVCRLGGI KHLVDLLDHR VLEVQKNACG ALRNLVFGKS
TDENKIAMKN VGGIPALLRL LRKSIDAEVR ELVTGVLWNL SSCDAVKMTI IRDALSTLTN
TVIVPHSGWN NSSFDDDHKI KFQTSLVLRN TTGCLRNLSS AGEEARKQMR SCEGLVDSLL
YVIHTCVNTS DYDSKTVENC VCTLRNLSYR LELEVPQARL LGLNELDDLL GKESPSKDSE
PSCWGKKKKK KKRTPQEDQW DGVGPIPGLS KSPKGVEMLW HPSVVKPYLT LLAESSNPAT
LEGSAGSLQN LSAGNWKFAA YIRAAVRKEK GLPILVELLR MDNDRVVSSV ATALRNMALD
VRNKELIGKY AMRDLVNRLP GGNGPSVLSD ETMAAICCAL HEVTSKNMEN AKALADSGGI
EKLVNITKGR GDRSSLKVVK AAAQVLNTLW QYRDLRSIYK KDGWNQNHFI TPVSTLERDR
FKSHPSLSTT NQQMSPIIQS GSSKPSPIYI SSYSSPAREQ NRRLQHQQLY YSQDDSNRKN
FDAYRLYLQS PHSYEDPYFD DRVHFPASTD YSTQYGLKST TNYVDFYSTK RPSYRAEQYP
GSPDSWV
//
