ID   I0H0R3_ACTM4            Unreviewed;       991 AA.
AC   I0H0R3;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   SubName: Full=Putative LuxR-family transcriptional regulator {ECO:0000313|EMBL:BAL86600.1};
GN   OrderedLocusNames=AMIS_13800 {ECO:0000313|EMBL:BAL86600.1};
OS   Actinoplanes missouriensis (strain ATCC 14538 / DSM 43046 / CBS 188.64 /
OS   JCM 3121 / NBRC 102363 / NCIMB 12654 / NRRL B-3342 / UNCC 431).
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=512565 {ECO:0000313|EMBL:BAL86600.1, ECO:0000313|Proteomes:UP000007882};
RN   [1] {ECO:0000313|EMBL:BAL86600.1, ECO:0000313|Proteomes:UP000007882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NBRC 102363 /
RC   NCIMB 12654 / NRRL B-3342 / UNCC 431
RC   {ECO:0000313|Proteomes:UP000007882};
RA   Ohnishi Y., Ishikawa J., Sekine M., Hosoyama A., Harada T., Narita H.,
RA   Hata T., Konno Y., Tutikane K., Fujita N., Horinouchi S., Hayakawa M.;
RT   "Complete genome sequence of Actinoplanes missouriensis 431 (= NBRC
RT   102363).";
RL   Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AP012319; BAL86600.1; -; Genomic_DNA.
DR   AlphaFoldDB; I0H0R3; -.
DR   STRING; 512565.AMIS_13800; -.
DR   KEGG; ams:AMIS_13800; -.
DR   PATRIC; fig|512565.3.peg.1387; -.
DR   eggNOG; COG0457; Bacteria.
DR   eggNOG; COG2197; Bacteria.
DR   eggNOG; COG3899; Bacteria.
DR   HOGENOM; CLU_006850_0_2_11; -.
DR   OrthoDB; 5476461at2; -.
DR   Proteomes; UP000007882; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007882}.
FT   DOMAIN          922..987
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50043"
SQ   SEQUENCE   991 AA;  105290 MW;  AD17CB31C2961793 CRC64;
     MLDLMTASTP STVLVGREAD LGVLREALKR VRGDEPAAVL VGGEAGVGKT RLVEEFCRSL
     DGEPVRVLQG QCLELGEEGL PFAPFAAALR ELARHEGRAV FDGREAEFAR LLPELGPPPD
     FQEARRGHLF ELVGALFARL AEEQPVILEI EDLHWADRST RDLIGFLLRS VRVRRLLLIA
     TYRTDELHRG HPLRPFLAEL DRVRGVQRLE VDRLDRDGTA ELLGHLLGLE PDPATVDAVA
     ERAQGIPFFI EQFASSADPG CGDIPETLRD LLLSRVDQLP EAAQRVLRVA AVGGTQFGHE
     LLARVAGVDE ATLESALRAT VAAQLIVFDP TGGYEFRHAL VREAVHDDLL PGEHARLHAR
     YAQTIESEPH LVAPDRAPAE IAHHWHAAHD HPRALVAARR AAESASCRYA FAEQARLLER
     VLELWEQVPE AATLLGTTHL DLLEETALVA IDAGDHLRAL SLTRAAIGDL DCEAEPLRAA
     RLLIRRAKLL RNAGKSDGAA EAREAYRLLQ SAPRDAAWLR LVGDVAYQTA GIDGEAAARM
     AGELRSAAAD LGDEASQVHA EITFGQVCGG RLPADQAVPT MRQAVERARA AGDVSNCSHG
     VVNLSDSLFE LGDYAESAAV AAEGIPDADR VGVSRTTGVY LLVNYAEALM ALGRWDEADA
     RLAEAARQDP PGVLAVAWLR LRARIRLARG HDGAAALVTR AVGFLAKPFL TAEHRVTLLE
     LRLLAALASG DTAAALQFAR ASVHDKGVFE RPRYGWALLV AASRAADEPL RAEIRELAAA
     LPARYPAERA AAAEVAALIG TAPDDGGPVD ACFSGGPSAG AGASGGGSGA GGSAGGGAGL
     GGVEAWRAAV AARRVDGQPY QLAGALLGYA EAVAGDRQAA SEALQEAAEI AERLGAGPML
     AAVDVLGRRL GVRAGVAHVP EQRGDGEVLT AREREVLRLV AEGQSNSGIA RELFISPKTA
     SVHVSRIIAK LEVSNRLEAA AVARRLGMLE S
//