ID I0H6J8_ACTM4 Unreviewed; 752 AA.
AC I0H6J8;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Putative diguanylate cyclase/phosphodiesterase with PAS sensor {ECO:0000313|EMBL:BAL88635.1};
GN OrderedLocusNames=AMIS_34150 {ECO:0000313|EMBL:BAL88635.1};
OS Actinoplanes missouriensis (strain ATCC 14538 / DSM 43046 / CBS 188.64 /
OS JCM 3121 / NBRC 102363 / NCIMB 12654 / NRRL B-3342 / UNCC 431).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=512565 {ECO:0000313|EMBL:BAL88635.1, ECO:0000313|Proteomes:UP000007882};
RN [1] {ECO:0000313|EMBL:BAL88635.1, ECO:0000313|Proteomes:UP000007882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NBRC 102363 /
RC NCIMB 12654 / NRRL B-3342 / UNCC 431
RC {ECO:0000313|Proteomes:UP000007882};
RA Ohnishi Y., Ishikawa J., Sekine M., Hosoyama A., Harada T., Narita H.,
RA Hata T., Konno Y., Tutikane K., Fujita N., Horinouchi S., Hayakawa M.;
RT "Complete genome sequence of Actinoplanes missouriensis 431 (= NBRC
RT 102363).";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP012319; BAL88635.1; -; Genomic_DNA.
DR AlphaFoldDB; I0H6J8; -.
DR STRING; 512565.AMIS_34150; -.
DR KEGG; ams:AMIS_34150; -.
DR PATRIC; fig|512565.3.peg.3411; -.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_49_11; -.
DR OrthoDB; 23692at2; -.
DR Proteomes; UP000007882; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08448; PAS_4; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007882};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 49..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 264..316
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 345..471
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 480..735
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 752 AA; 80811 MW; 3CDD7CEFA09B3DD2 CRC64;
MKWLRDRLPT GGGLRDEDWA SRHRLLTVLL AAVLVFLIMF GVLRGEGHTL TLLLTVVPVL
PCLLAASRLR SRRLRAVCVA IGYTIACGGF VALCHGLTEA HFSFFIAVAA LALYRDWAPF
GAFLVATTLH HAVFGSLVSD HTYDHGSAVA HPLVWALLHG ASVLLAAGFQ IVSWRLTEVE
EDRARENLDE SQAQLSVAFD ATPVPMAMFS PDGLALRTNA AYRVWLGLPE ELPAGFGLKD
IPLIPVDGDQ ASILTLFAES RESRTITRQY RRPDGSLIWV EVHGTGLYDR NDQLRLIYVH
CFDVTATRDH EAELSYQVRH DTLTGLLSRK AFEHDLAALL TGSTEPVSVI YLDVDRFKVI
NDGAGHTTGD DVLRALATRL AAVVPAGAVL ARLGGDEFVV ALTGPAGTGL RVGNSILAAV
HEPVAGVPVS LSIGVTTAFG GVGADEVVLA ADTAMYAAKR AGGNRLQVFT EDLRVPVQER
IAAEARLRRA LAGDPRSTLP LWFQPVVSTA TGQIVGAEAL VRMRTEQGTV LAPGLFIGAA
EETGLIVPLG DHVLRSAVEH LVHWSDRLGY VSVNVSPRQL AEPDFVPKVA SLLAEYPYLD
PSRLVLEVTE TALISSTVDV SERLALLKQL GVRIALDDFG TGYSSLTWLK SLPADVVKLD
RSFVAGLAED ARKASIISAV LWLARSLGMS TIAEGVEEIA DWDALRAAGC PAIQGYLISK
PLPAPEFDML LTTGSPFRGV HLDETTGHVL AG
//
