ID I0HXQ2_RUBGI Unreviewed; 348 AA.
AC I0HXQ2;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:BAL97789.1};
GN Name=cobW {ECO:0000313|EMBL:BAL97789.1};
GN OrderedLocusNames=RGE_44530 {ECO:0000313|EMBL:BAL97789.1};
OS Rubrivivax gelatinosus (strain NBRC 100245 / IL144).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Rubrivivax.
OX NCBI_TaxID=983917 {ECO:0000313|EMBL:BAL97789.1, ECO:0000313|Proteomes:UP000007883};
RN [1] {ECO:0000313|EMBL:BAL97789.1, ECO:0000313|Proteomes:UP000007883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 100245 / IL144 {ECO:0000313|Proteomes:UP000007883};
RX PubMed=22689232; DOI=10.1128/JB.00511-12;
RA Nagashima S., Kamimura A., Shimizu T., Nakamura-isaki S., Aono E.,
RA Sakamoto K., Ichikawa N., Nakazawa H., Sekine M., Yamazaki S., Fujita N.,
RA Shimada K., Hanada S., Nagashima K.V.P.;
RT "Complete genome sequence of phototrophic betaproteobacterium Rubrivivax
RT gelatinosus IL144.";
RL J. Bacteriol. 194:3541-3542(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; AP012320; BAL97789.1; -; Genomic_DNA.
DR RefSeq; WP_014430637.1; NC_017075.1.
DR AlphaFoldDB; I0HXQ2; -.
DR STRING; 983917.RGE_44530; -.
DR KEGG; rge:RGE_44530; -.
DR PATRIC; fig|983917.3.peg.4340; -.
DR eggNOG; COG0523; Bacteria.
DR HOGENOM; CLU_017452_1_0_4; -.
DR Proteomes; UP000007883; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR012824; CobW.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02475; CobW; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR PANTHER; PTHR13748:SF70; PROTEIN COBW; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000007883}.
FT DOMAIN 254..345
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
SQ SEQUENCE 348 AA; 37475 MW; 55BE04029B1603DA CRC64;
MHKIPATIVT GFLGAGKTTL LRHLLTNAGG RRIAVIVNEF GELGIDGELL RGCGIGCDEE
GRDDGNLVEL ANGCLCCTVQ EEFAPVMERL AERRDRIDHL VIETSGLALP KPLVQAFQWP
TLRHAFTVDA VVTVVDAPAV AEGRFADDPQ AVDLQRRADD NLDHESPLAE LFADQLATAD
LVVLNKTDVL DAAALAAVEA QVRAGAPAAV KLLAAQHGRL APDVLLGLGR AVEDSIDARR
THHDEEEDHD HDEFDSVALT VEVTDRERLL QALAALVSRH EIYRAKGFVA LPGAAMRLVV
QGVGARLDSH FDRAWRPGEA RVSRLVLIGA ELDAAVLQRE LQQALSAG
//
