ID I0I3L9_CALAS Unreviewed; 412 AA.
AC I0I3L9;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=NADH:ubiquinone reductase (non-electrogenic) {ECO:0000256|ARBA:ARBA00012637};
DE EC=1.6.5.9 {ECO:0000256|ARBA:ARBA00012637};
GN OrderedLocusNames=CLDAP_18170 {ECO:0000313|EMBL:BAL99856.1};
OS Caldilinea aerophila (strain DSM 14535 / JCM 11387 / NBRC 104270 /
OS STL-6-O1).
OC Bacteria; Chloroflexota; Caldilineae; Caldilineales; Caldilineaceae;
OC Caldilinea.
OX NCBI_TaxID=926550 {ECO:0000313|EMBL:BAL99856.1, ECO:0000313|Proteomes:UP000007880};
RN [1] {ECO:0000313|EMBL:BAL99856.1, ECO:0000313|Proteomes:UP000007880}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1
RC {ECO:0000313|Proteomes:UP000007880};
RA Oguchi A., Hosoyama A., Sekine M., Fukai R., Kato Y., Nakamura S.,
RA Hanada S., Yamazaki S., Fujita N.;
RT "Complete genome sequence of Caldilinea aerophila DSM 14535 (= NBRC
RT 102666).";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a quinone + H(+) + NADH = a quinol + NAD(+);
CC Xref=Rhea:RHEA:46160, ChEBI:CHEBI:15378, ChEBI:CHEBI:24646,
CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:132124; EC=1.6.5.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000864};
CC -!- SIMILARITY: Belongs to the NADH dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00005272}.
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DR EMBL; AP012337; BAL99856.1; -; Genomic_DNA.
DR RefSeq; WP_014433094.1; NC_017079.1.
DR AlphaFoldDB; I0I3L9; -.
DR STRING; 926550.CLDAP_18170; -.
DR KEGG; cap:CLDAP_18170; -.
DR PATRIC; fig|926550.5.peg.2022; -.
DR eggNOG; COG1252; Bacteria.
DR HOGENOM; CLU_021377_7_1_0; -.
DR OrthoDB; 9784880at2; -.
DR Proteomes; UP000007880; Chromosome.
DR GO; GO:0003954; F:NADH dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006116; P:NADH oxidation; IEA:InterPro.
DR Gene3D; 3.50.50.100; -; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR045024; NDH-2.
DR PANTHER; PTHR43706:SF3; EXTERNAL NADH-UBIQUINONE OXIDOREDUCTASE 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43706; NADH DEHYDROGENASE; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000007880}.
FT DOMAIN 6..322
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 412 AA; 45293 MW; A2AAA069542F700C CRC64;
MSETPRVVVV GAGFGGLWAA RALSCAPVRV LLLDRNNYHT FLPLLYQVAA AELEPEAIAY
PVRSILRRMP NTNFALAEVQ AVDLASRCLE TSAGAISYDY LILAAGSTTH FFGTPGAEAH
ALPLKSMADA IAIRNRVLLS YEKANLESDP ERRQQILTFV IVGGGPTGVE FASALAELIN
GPLRRDFPFL SSSPGRVVLV EAMEALLPGF HPHLQDYAAK RLRRIGVEVL LGAPVTRIDE
STVTLKDEMR ITAETIVWTA GVQGILPVAR WGFPVVKSGR VAVLPTLQTP DHPEVYVVGD
LAYLEQKSAP LPMVAPVAIQ QGKWAAQNIL RQVHGQQPLP FRYRDRGAMV TIGRNAAAAQ
LGSLKFTGFP AWVLWLTVHL FNLVGFRNRL VVMLNWAWDY FFFERIARLI LP
//
