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Database: UniProt
Entry: I0IBT8_PHYMF
LinkDB: I0IBT8_PHYMF
Original site: I0IBT8_PHYMF 
ID   I0IBT8_PHYMF            Unreviewed;       595 AA.
AC   I0IBT8;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   25-OCT-2017, entry version 40.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577};
GN   OrderedLocusNames=PSMK_05670 {ECO:0000313|EMBL:BAM02726.1};
OS   Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 /
OS   FYK2301M01).
OC   Bacteria; Planctomycetes; Phycisphaerae; Phycisphaerales;
OC   Phycisphaeraceae; Phycisphaera.
OX   NCBI_TaxID=1142394 {ECO:0000313|EMBL:BAM02726.1, ECO:0000313|Proteomes:UP000007881};
RN   [1] {ECO:0000313|EMBL:BAM02726.1, ECO:0000313|Proteomes:UP000007881}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 102666 / KCTC 22515 / FYK2301M01
RC   {ECO:0000313|Proteomes:UP000007881};
RA   Ankai A., Hosoyama A., Terui Y., Sekine M., Fukai R., Kato Y.,
RA   Nakamura S., Yamada-Narita S., Kawakoshi A., Fukunaga Y., Yamazaki S.,
RA   Fujita N.;
RT   "Complete genome sequence of Phycisphaera mikurensis NBRC 102666.";
RL   Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|RuleBase:RU000577,
CC       ECO:0000256|SAAS:SAAS00747914}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; AP012338; BAM02726.1; -; Genomic_DNA.
DR   EnsemblBacteria; BAM02726; BAM02726; PSMK_05670.
DR   KEGG; phm:PSMK_05670; -.
DR   KO; K02313; -.
DR   OMA; AGKEHTQ; -.
DR   OrthoDB; POG091H06G0; -.
DR   BioCyc; PMIK1142394:GLIF-573-MONOMER; -.
DR   Proteomes; UP000007881; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 2.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007881};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007881}.
FT   DOMAIN      490    559       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   595 AA;  60167 MW;  A88712452C5BFD66 CRC64;
     MSALPSLPPL PDEPAAGLPG KTAPAGPRLA DAGGRAAGTG NGPPALTPDL RERLLGPLEA
     RFGVGRVSLW IDGGRGLGLD PETGALTLAV PHRFAADRLR QGGLAHALSE AAAGAGLPSC
     AADAETQPAA GPGCDPAAAG APGAGRGPHP HLRLVVGPSP TDAAAEAGGG AAEGVSAGRP
     AAPAAPAGTP GRRPARGGGA RTGRAGGGAT RRRGGSATPG QRFGNFVTGP CNELGFAAAS
     ALASGDHDGP LFVHGPCGTG KTHLVTGLVA AWRERCPGSR VVHTTGERFT NRFIEHARRG
     TLAAFRREFR GCHLLAVDDV HFIAGKQKTQ HELLHCFDAA LSAGVPVVFA SDRHPRQLQE
     MGTPLSSRCL QGLVAELEAP APAMRRTLIA ELGARRGLRI DADAAAALEP LAGPGVREIE
     GLLAKLDVLD RLGPGGRLKA MAPPPGRTAA AGAAPAGAPG RPVGAALVER LRRLERPGPP
     PRRLNPGPAG VATIAEIVGE ALGVEPREAL GAGRSRVVVQ ARALVAHLAR ELTAMSYPEI
     ARAMGRPSHS GVITADKRVR SQAEADAAVP VAGGGEPVPV RRLLADLRAR LRAAG
//
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