ID I0J0A0_9MURI Unreviewed; 559 AA.
AC I0J0A0;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 22-FEB-2023, entry version 29.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
DE Flags: Fragment;
GN Name=DDX3Y {ECO:0000313|EMBL:BAM10949.1};
OS Tokudaia muenninki (Okinawa island spiny rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Tokudaia.
OX NCBI_TaxID=742503 {ECO:0000313|EMBL:BAM10949.1};
RN [1] {ECO:0000313|EMBL:BAM10949.1}
RP NUCLEOTIDE SEQUENCE.
RA Murata C., Yamada F., Kawauchi N., Matsuda Y., Kuroiwa A.;
RT "The Y chromosome of the Okinawa spiny rat, Tokudaia muenninki, avoided a
RT crisis of loss by fusion with autosome.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DEAD box helicase family.
CC {ECO:0000256|RuleBase:RU000492}.
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DR EMBL; AB672502; BAM10949.1; -; mRNA.
DR AlphaFoldDB; I0J0A0; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd18051; DEADc_DDX3; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR PANTHER; PTHR47958; ATP-DEPENDENT RNA HELICASE DBP3; 1.
DR PANTHER; PTHR47958:SF18; ATP-DEPENDENT RNA HELICASE DDX3Y; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 2: Evidence at transcript level;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU000492};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|RuleBase:RU000492};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000492};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000492}.
FT DOMAIN 81..109
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 112..304
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 315..476
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 482..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 81..109
FT /note="Q motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00552"
FT COMPBIAS 1..43
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 500..529
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:BAM10949.1"
SQ SEQUENCE 559 AA; 62839 MW; D1EE0E6BCE717AAF CRC64;
RGRFDDLGRS DYDGIGGRDR TGFGKFRWGD RSDEDDWSKP LPPSERLEQE LFSGGNTGIN
FEKYDDIPVE ATGNNCPPHI ENFSDVEMGE IIMGNIELTR YTRPTPVQKH AIPIIKEKRD
LMACAQTGSG KTAAFLLPIL SQIYTDGPGE ALKAMKENGR YGRRKQYPIS LVLAPTRELA
VQIYEEARKF SYRSRVRPCV VYGGADTVQQ IRDLERGCHL LVATPGRLVD MMERGKIGLD
FCKYLVLDEA DRMLDMGFEP QIRRIVEQDT MPPKGVRHTM MFSATFPKEI QMLARDFLDE
YIFLAVGRVG STSENITQKV VWVEELDKRS FLLDLLNATG KDSLTLVFVE TKKGADSLEN
FLFQERYSCT SIHGDRSQKD REEALHQFRS GRKPILVATA VAARGLDISN VKHVINFDLP
SDIEEYVHRI GRTGRVGNLG LATSFFNERN LNITKDLLDL LVEAKQEVPS WLESMAYEHH
YKGSSRGRPK RFSGGFGARD YRQSSGSANS GFNTNRANSS RSSGSSHNRG FGGGGYGSFY
NNDGYGGNYN SQAVDWWGN
//
