ID I0JLG2_HALH3 Unreviewed; 276 AA.
AC I0JLG2;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 59.
DE SubName: Full=LysR family transcription regulator {ECO:0000313|EMBL:CCG44982.1};
GN OrderedLocusNames=HBHAL_2631 {ECO:0000313|EMBL:CCG44982.1};
OS Halobacillus halophilus (strain ATCC 35676 / DSM 2266 / JCM 20832 / KCTC
OS 3685 / LMG 17431 / NBRC 102448 / NCIMB 2269) (Sporosarcina halophila).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Halobacillus.
OX NCBI_TaxID=866895 {ECO:0000313|EMBL:CCG44982.1, ECO:0000313|Proteomes:UP000007397};
RN [1] {ECO:0000313|EMBL:CCG44982.1, ECO:0000313|Proteomes:UP000007397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35676 / DSM 2266 / JCM 20832 / KCTC 3685 / LMG 17431 /
RC NBRC 102448 / NCIMB 2269 {ECO:0000313|Proteomes:UP000007397};
RX PubMed=22583374; DOI=10.1111/j.1462-2920.2012.02770.x;
RA Saum S.H., Pfeiffer F., Palm P., Rampp M., Schuster S.C., Muller V.,
RA Oesterhelt D.;
RT "Chloride and organic osmolytes: a hybrid strategy to cope with elevated
RT salinities by the moderately halophilic, chloride-dependent bacterium
RT Halobacillus halophilus.";
RL Environ. Microbiol. 15:1619-1633(2013).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; HE717023; CCG44982.1; -; Genomic_DNA.
DR RefSeq; WP_014642876.1; NC_017668.1.
DR AlphaFoldDB; I0JLG2; -.
DR STRING; 866895.HBHAL_2631; -.
DR KEGG; hhd:HBHAL_2631; -.
DR PATRIC; fig|866895.3.peg.1648; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_2_9; -.
DR Proteomes; UP000007397; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd05466; PBP2_LTTR_substrate; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30346:SF16; SMALL NEUTRAL PROTEASE REGULATORY PROTEIN; 1.
DR PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007397}.
FT DOMAIN 1..58
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 276 AA; 31820 MW; 2E22C77439258457 CRC64;
MLLHKIKYFL EIAEWRSFTK AAEIFYISQP ALSKQMKLLE EELGFPLFDR SVRGVDLTDK
GHALYKDLKP LFAQIERTIH HYRDHDQIRF GSTPMISSYF IHRHYDKLIQ TNFHVTTIKD
DSRDLLPLLE ADEIDAAIIQ DEPSYSNLYS KFLFRDNFLA AVPLTSKLAS LEEVTIEQCM
KEPQIIPPEG SLTNQLKTIM EEKQFKGETI ETQYHAMAGL VSLGLGIAYL PEIMVEQIEY
KGVVFLPING QPLARNMYLY AVTLPILEFL EGKLTN
//
