ID I0JNB1_HALH3 Unreviewed; 75 AA.
AC I0JNB1;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Transcription attenuation protein MtrB {ECO:0000256|HAMAP-Rule:MF_00798};
DE AltName: Full=Trp RNA-binding attenuation protein {ECO:0000256|HAMAP-Rule:MF_00798};
DE Short=TRAP {ECO:0000256|HAMAP-Rule:MF_00798};
DE AltName: Full=Tryptophan RNA-binding attenuator protein {ECO:0000256|HAMAP-Rule:MF_00798};
GN Name=mtrB {ECO:0000256|HAMAP-Rule:MF_00798,
GN ECO:0000313|EMBL:CCG45631.1};
GN OrderedLocusNames=HBHAL_3285 {ECO:0000313|EMBL:CCG45631.1};
OS Halobacillus halophilus (strain ATCC 35676 / DSM 2266 / JCM 20832 / KCTC
OS 3685 / LMG 17431 / NBRC 102448 / NCIMB 2269) (Sporosarcina halophila).
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Halobacillus.
OX NCBI_TaxID=866895 {ECO:0000313|EMBL:CCG45631.1, ECO:0000313|Proteomes:UP000007397};
RN [1] {ECO:0000313|EMBL:CCG45631.1, ECO:0000313|Proteomes:UP000007397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35676 / DSM 2266 / JCM 20832 / KCTC 3685 / LMG 17431 /
RC NBRC 102448 / NCIMB 2269 {ECO:0000313|Proteomes:UP000007397};
RX PubMed=22583374; DOI=10.1111/j.1462-2920.2012.02770.x;
RA Saum S.H., Pfeiffer F., Palm P., Rampp M., Schuster S.C., Muller V.,
RA Oesterhelt D.;
RT "Chloride and organic osmolytes: a hybrid strategy to cope with elevated
RT salinities by the moderately halophilic, chloride-dependent bacterium
RT Halobacillus halophilus.";
RL Environ. Microbiol. 15:1619-1633(2013).
CC -!- FUNCTION: Required for transcription attenuation control in the Trp
CC operon. This trans-acting factor seems to recognize a 10 bases
CC nucleotide sequence in the Trp leader transcript causing transcription
CC termination. Binds the leader RNA only in presence of L-tryptophan.
CC {ECO:0000256|HAMAP-Rule:MF_00798}.
CC -!- SUBUNIT: Oligomer of 11 identical subunits arranged in doughnut-like
CC structure. {ECO:0000256|ARBA:ARBA00011104, ECO:0000256|HAMAP-
CC Rule:MF_00798}.
CC -!- SIMILARITY: Belongs to the MtrB family. {ECO:0000256|ARBA:ARBA00010027,
CC ECO:0000256|HAMAP-Rule:MF_00798}.
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DR EMBL; HE717023; CCG45631.1; -; Genomic_DNA.
DR RefSeq; WP_014643522.1; NC_017668.1.
DR AlphaFoldDB; I0JNB1; -.
DR STRING; 866895.HBHAL_3285; -.
DR KEGG; hhd:HBHAL_3285; -.
DR PATRIC; fig|866895.3.peg.2303; -.
DR eggNOG; ENOG5032Z9Y; Bacteria.
DR HOGENOM; CLU_180875_0_0_9; -.
DR Proteomes; UP000007397; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription termination; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.60.40.50; TRAP-like; 1.
DR HAMAP; MF_00798; Trp_attenuator; 1.
DR InterPro; IPR000824; MtrB.
DR InterPro; IPR016031; Trp_RNA-bd_attenuator-like_dom.
DR InterPro; IPR023558; Trp_RNA-bd_attenuator_dom.
DR Pfam; PF02081; TrpBP; 1.
DR PRINTS; PR00687; TRPRNAAP.
DR SUPFAM; SSF51219; TRAP-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007397};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00798};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00798};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00798}.
FT DOMAIN 5..72
FT /note="Tryptophan RNA-binding attenuator protein"
FT /evidence="ECO:0000259|Pfam:PF02081"
SQ SEQUENCE 75 AA; 8292 MW; 06512A6B0C580D19 CRC64;
MTTSNNDFFV IKALEDGVNV IGLTRGTDTR FHHSEKLDQG EVMIAQFTEH TSAVKVRGKA
VIQTSHGEMT NEGEE
//
