ID I0K5N0_9BACT Unreviewed; 922 AA.
AC I0K5N0;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 71.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=FAES_1423 {ECO:0000313|EMBL:CCG99433.1};
OS Fibrella aestuarina BUZ 2.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC Fibrella.
OX NCBI_TaxID=1166018 {ECO:0000313|EMBL:CCG99433.1, ECO:0000313|Proteomes:UP000011058};
RN [1] {ECO:0000313|EMBL:CCG99433.1, ECO:0000313|Proteomes:UP000011058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BUZ 2T {ECO:0000313|Proteomes:UP000011058};
RX PubMed=22689241; DOI=10.1128/JB.00550-12;
RA Filippini M., Qi W., Blom J., Goesmann A., Smits T.H., Bagheri H.C.;
RT "Genome Sequence of Fibrella aestuarina BUZ 2T, a Filamentous Marine
RT Bacterium.";
RL J. Bacteriol. 194:3555-3555(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; HE796683; CCG99433.1; -; Genomic_DNA.
DR RefSeq; WP_015330532.1; NC_020054.1.
DR AlphaFoldDB; I0K5N0; -.
DR STRING; 1166018.FAES_1423; -.
DR KEGG; fae:FAES_1423; -.
DR PATRIC; fig|1166018.3.peg.3154; -.
DR eggNOG; COG0745; Bacteria.
DR eggNOG; COG1879; Bacteria.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_000445_28_7_10; -.
DR OrthoDB; 9797097at2; -.
DR Proteomes; UP000011058; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd06308; PBP1_sensor_kinase-like; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 3.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR025997; SBP_2_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12833; HTH_18; 1.
DR Pfam; PF13407; Peripla_BP_4; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000011058};
KW Transferase {ECO:0000313|EMBL:CCG99433.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 355..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 420..635
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 677..792
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 820..919
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
FT COILED 334..413
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 725
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 922 AA; 104106 MW; 5CF536F7AF5CA8E2 CRC64;
MFHQQNRRVV CQWRFVIQQF YLVIGAALSL LGCADPTPET TYRIGFSQRT TADTWRRTML
DNMNQELSFS PDVAFIVKDA GGQSARQAAQ IQELLDQQID LLIVSPNSAQ PITPVVEKAY
QQGIPVVVLD RRTASDQYTA YVGADNVEVG RTAGMYASNL LKGRGTVVEI GESPGSSADT
DRHRGFMEAI RQTPGIQVVR KLAGDWDKQS FDDQLTRLLT AQPTVDLIFS QNDRMALKAY
RVCQRVGLAD RVTIIGVDGL PGQNEGIDLV DRGVLNATVL YPTGGREAIR TALAILKKQP
FKRENRLPIT LIDSTNVPTM KLQNDKVIEQ QLDIDRQHKR ISDLNRTYSN QRNRLYVTLV
SLLIVIVLGA YALYLVREKQ TAYQRLTQQT EEIRQQKDQI EAVSKQARLA TEEKLRFYSY
ISHEFNTPLS LILTPTEDML TRKQTDSREV RSNLQLIRKN AHRLLRLVDQ MLDLRRADAG
KLLLRAQEGD IVGFTREIVQ DFQAKADKLR IDLRLLTTEP QLALWFDPEK LDKVLFNLLS
NAVKYTPRGG FIHVRLTRTD DTVQLQVQDN GEGMTPDEQT RIFDLFYTSN TNFTLGNGLG
LALSREFVSL HHGDLQVESA KDKGTTFTLT LPLGNAHLDA SELGTPGTSA TYLPADDDWQ
ETEPIISPPV GRNKAGTLLI IEDHDDLRQY LTTRLGDHFE ILAEPSAERG WEQILDTLPD
LIISDIMLPG ISGLQLTQQI KADFRTSTIP VILLTAKGQM NERIEGTRAG ADAYIAKPFQ
MTYLLETINT ILANRAKWQN RYTGDYLAKT ENRQEKKFLN ELTTLIEQHL ADPAFGVEQL
SREMGLSRVQ LYRKAQTLLG RNVNDYFAEI RLKKAKVLLT ETGKPIAEIA YETGFSSPAY
FTTFFKQHTQ RTPSEFRKAA IA
//
