ID   I0KW24_9ACTN            Unreviewed;       319 AA.
AC   I0KW24;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=Putative quinone oxidoreductase, NADPH-dependent {ECO:0000313|EMBL:CCH15771.1};
GN   ORFNames=MILUP08_40681 {ECO:0000313|EMBL:CCH15771.1};
OS   Micromonospora lupini str. Lupac 08.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=1150864 {ECO:0000313|EMBL:CCH15771.1, ECO:0000313|Proteomes:UP000003448};
RN   [1] {ECO:0000313|Proteomes:UP000003448}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lupac 08 {ECO:0000313|Proteomes:UP000003448};
RX   PubMed=22815450; DOI=10.1128/jb.00628-12;
RA   Alonso-Vega P., Normand P., Bacigalupe R., Pujic P., Lajus A., Vallenet D.,
RA   Carro L., Coll P., Trujillo M.E.;
RT   "Genome Sequence of Micromonospora lupini Lupac 08, Isolated from Root
RT   Nodules of Lupinus angustifolius.";
RL   J. Bacteriol. 194:4135-4135(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCH15771.1}.
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DR   EMBL; CAIE01000009; CCH15771.1; -; Genomic_DNA.
DR   RefSeq; WP_007455113.1; NZ_HF570108.1.
DR   AlphaFoldDB; I0KW24; -.
DR   STRING; 1150864.MILUP08_40681; -.
DR   eggNOG; COG0604; Bacteria.
DR   OrthoDB; 3339625at2; -.
DR   Proteomes; UP000003448; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR48106; QUINONE OXIDOREDUCTASE PIG3-RELATED; 1.
DR   PANTHER; PTHR48106:SF13; QUINONE OXIDOREDUCTASE-RELATED; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF13602; ADH_zinc_N_2; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003448}.
FT   DOMAIN          10..315
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   319 AA;  32716 MW;  1DE14B0651DE6870 CRC64;
     MRAVRFAAYG EPAVLTPVEL PVPEPGPGQV LVRVAYAGVN FAEVMFRRGQ IPVGLPHVPG
     LEVTGTVERV GADVRGLAAG ARVAALTLDG GGYAEYALAR ADLAIELDGP LDRLSPVLAA
     AFPCNVPVAW GVVHAAARVL PAETVLITAP AGGVGTAAAQ LARSAGAGAV HGVTSSTTKA
     AYAAGFGYDE VWVGEVPAGR TFDVVLDSVG GDVRQRALEL LAPFGRYVVL GDAADAGDQT
     FAGNQLWGSG ASVGGYNLGG LAHQRPDLLG EHLRQAALSV ATGAVRIDVT EVPLADVAKV
     HELLESRRST GKYVLRVHD
//