ID I0L037_9ACTN Unreviewed; 420 AA.
AC I0L037;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=ROK family sugar kinase {ECO:0000313|EMBL:CCH17184.1};
GN ORFNames=MILUP08_42104 {ECO:0000313|EMBL:CCH17184.1};
OS Micromonospora lupini str. Lupac 08.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1150864 {ECO:0000313|EMBL:CCH17184.1, ECO:0000313|Proteomes:UP000003448};
RN [1] {ECO:0000313|Proteomes:UP000003448}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lupac 08 {ECO:0000313|Proteomes:UP000003448};
RX PubMed=22815450; DOI=10.1128/jb.00628-12;
RA Alonso-Vega P., Normand P., Bacigalupe R., Pujic P., Lajus A., Vallenet D.,
RA Carro L., Coll P., Trujillo M.E.;
RT "Genome Sequence of Micromonospora lupini Lupac 08, Isolated from Root
RT Nodules of Lupinus angustifolius.";
RL J. Bacteriol. 194:4135-4135(2012).
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCH17184.1}.
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DR EMBL; CAIE01000017; CCH17184.1; -; Genomic_DNA.
DR AlphaFoldDB; I0L037; -.
DR STRING; 1150864.MILUP08_42104; -.
DR eggNOG; COG1846; Bacteria.
DR eggNOG; COG1940; Bacteria.
DR Proteomes; UP000003448; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000835; HTH_MarR-typ.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF12802; MarR_2; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:CCH17184.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003448};
KW Transferase {ECO:0000313|EMBL:CCH17184.1}.
FT DOMAIN 39..88
FT /note="HTH marR-type"
FT /evidence="ECO:0000259|Pfam:PF12802"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 420 AA; 43286 MW; 2C127D2E5197829D CRC64;
METPVRSRPA GAGRNPESPL PPVPGASQEE IRRQNLGAVL RYVHLHGPTS RAELTSRLGL
NRSTIGALAA DLTASGLVTE EAPTTARRAG RPSLVVSPRS DRVYAHALSI DADRLRAARV
GLGGRILDLR EVARPGGMSA VDAVGPLADL VRDMERGVAS DALLVGGAVA VTDTTRDADG
RLRIVGVDEG LSVALEAELT AGPGFVAGDL ADIAGLAEHI RGVAPGIDDL IYLHGDLGIS
AGIVVGGRLM IGHRGHSGKV GHMVVNPNGL PCGCGSRGCW ETEIGEAALL RHAGRDPDDR
AAVTEVLRAA ADGDPAALRA VEQVADWLGF GVANLVNVVN PDAVVFGGSL RDIFIAGADT
VRRRLDAMPL PASREHLRLR AAALGRDAVL IGAAELAFDK LLADPLNVGV VGQAGSAEPA
//
