ID I0R6B3_9FIRM Unreviewed; 322 AA.
AC I0R6B3;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=HMPREF9970_1558 {ECO:0000313|EMBL:EIC95221.1};
OS Lachnoanaerobaculum saburreum F0468.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Lachnoanaerobaculum.
OX NCBI_TaxID=1095750 {ECO:0000313|EMBL:EIC95221.1, ECO:0000313|Proteomes:UP000005039};
RN [1] {ECO:0000313|EMBL:EIC95221.1, ECO:0000313|Proteomes:UP000005039}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0468 {ECO:0000313|EMBL:EIC95221.1,
RC ECO:0000313|Proteomes:UP000005039};
RA Durkin A.S., McCorrison J., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIC95221.1}.
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DR EMBL; AJGH01000091; EIC95221.1; -; Genomic_DNA.
DR RefSeq; WP_008754469.1; NZ_AJGH01000091.1.
DR AlphaFoldDB; I0R6B3; -.
DR PATRIC; fig|1095750.3.peg.1964; -.
DR eggNOG; COG2972; Bacteria.
DR OrthoDB; 9809348at2; -.
DR Proteomes; UP000005039; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EIC95221.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:EIC95221.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 7..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 36..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 201..315
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 322 AA; 37460 MW; 729C0EC71E9277C6 CRC64;
MRFFIKIIGM VGIVIVFSVA EIIYSTNVFL KIAEDFILIV IFLYLLKTFL AYSKLLDTSK
DVFDDDLMEN EFCNELINYI EKYTNEKIKK NIVEIFNKQT ELTALQSQIN PHFLYNTLDS
IRGEALCNDD DNVADMIATL GSFFRYSISK NGKMARLRDE LENVKNYMKI QEYRFRGRFH
LEIEVGEEDV NVYDCYVPRL ILQPIVENAI YHGLEGVRNG GIVRIEVNLI EKYLMIMIMD
NGRGMKVEEL KELNRRIFEG DYRKLIDNPN SNNTGIALPN IYKRINLLYG EDYGLTVYSS
FGQGTDVEIL LPIQLKAYED EL
//
