ID I0R6H1_9FIRM Unreviewed; 488 AA.
AC I0R6H1;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE SubName: Full=HAMP domain / histidine kinase / GHKL domain multi-domain protein {ECO:0000313|EMBL:EIC95279.1};
GN ORFNames=HMPREF9970_1317 {ECO:0000313|EMBL:EIC95279.1};
OS Lachnoanaerobaculum saburreum F0468.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Lachnoanaerobaculum.
OX NCBI_TaxID=1095750 {ECO:0000313|EMBL:EIC95279.1, ECO:0000313|Proteomes:UP000005039};
RN [1] {ECO:0000313|EMBL:EIC95279.1, ECO:0000313|Proteomes:UP000005039}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0468 {ECO:0000313|EMBL:EIC95279.1,
RC ECO:0000313|Proteomes:UP000005039};
RA Durkin A.S., McCorrison J., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIC95279.1}.
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DR EMBL; AJGH01000089; EIC95279.1; -; Genomic_DNA.
DR RefSeq; WP_008754439.1; NZ_AJGH01000089.1.
DR AlphaFoldDB; I0R6H1; -.
DR PATRIC; fig|1095750.3.peg.1934; -.
DR eggNOG; COG2972; Bacteria.
DR OrthoDB; 9809348at2; -.
DR Proteomes; UP000005039; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EIC95279.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 179..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 203..256
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 488 AA; 57403 MW; 42D70C67D0946B00 CRC64;
MKRKIFNQSI KYKIGIFIIA VITALIVDIR FDFFVVEYTS SGFGEILREI SVCYELQDAL
SVEKSQFVYY IRNRDNKEEL LKSCKKTDEI VDKLPLDIRY MDKERYSRVW SIKNSYPVYA
GKRREIIDSD YDAKDFIEKV YDIYEMQDYL ISYGERLMDI TLSENNEIYQ KQAKFFKRLP
FIIGIVLIPI IVWIIYMAIR LQALILSPIN KMVEISKNIA KNIFFDKDIV VKNKDEMGDL
VNAFNKMKHA TAGYITGLEE RYELSELLHK EAMEKMKMEK RLNEARFDLL KSQINPHFLF
NTLNIIAASA NLEDAKDTED MIRALGNIFR YSLKTDEKQV SLERELSIVK DYMYIQKMRF
GDRISYEIVS KVENDKVYIP SFSLQPIVEN AIVHGISKKE EGGKVVIRVW ERDYMLHIIV
ADTGVGMRKE RLFELRDFMK KRSTAKIGIG FGNIYKRIKN IYKTGDLRIY SKEGKMTVVY
FMIPQISI
//
