ID I0RFJ9_MYCXE Unreviewed; 579 AA.
AC I0RFJ9;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=3-ketosteroid-delta-1-dehydrogenase {ECO:0000313|EMBL:EID09902.1};
GN ORFNames=MXEN_18204 {ECO:0000313|EMBL:EID09902.1};
OS Mycobacterium xenopi RIVM700367.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1150591 {ECO:0000313|EMBL:EID09902.1, ECO:0000313|Proteomes:UP000003584};
RN [1] {ECO:0000313|EMBL:EID09902.1, ECO:0000313|Proteomes:UP000003584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RIVM700367 {ECO:0000313|EMBL:EID09902.1,
RC ECO:0000313|Proteomes:UP000003584};
RX PubMed=22628510; DOI=10.1128/JB.00482-12;
RA Abdallah A.M., Rashid M., Adroub S.A., Elabdalaoui H., Ali S.,
RA van Soolingen D., Bitter W., Pain A.;
RT "Complete Genome Sequence of Mycobacterium xenopi Type Strain RIVM700367.";
RL J. Bacteriol. 194:3282-3283(2012).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EID09902.1}.
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DR EMBL; AJFI01000095; EID09902.1; -; Genomic_DNA.
DR RefSeq; WP_003922558.1; NZ_AJFI01000095.1.
DR AlphaFoldDB; I0RFJ9; -.
DR PATRIC; fig|1150591.3.peg.3665; -.
DR OrthoDB; 9813348at2; -.
DR Proteomes; UP000003584; Unassembled WGS sequence.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR GO; GO:0008202; P:steroid metabolic process; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000003584}.
FT DOMAIN 10..547
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 579 AA; 63211 MW; 53B2C3F075D0F880 CRC64;
MTGVFDHLVD VLVVGSGGGG MTAALAADAS GLDTLIVEKS SHFGGSTALS GGGIWVPGAP
AQKREGYSPS PGDVFEYLRQ ITGGLVSDAR LRQYVEAAPV MMEFLEQTSP WLEFVWKPGY
ADYYPELPGG SALGSTINVP AIDLRALGDE EQHLLAPLTL TPKGIWLGPK DLRLFYQIRQ
NWRGKAVLVK LIWRMARARL FGERMAAIGQ SLAARLRLAL KERGVPIWLG APMTELITDG
DGAVIGAVIE RDGLAQRIGA RRGVILATGG FDHDLDWRRR YLPVLEKDWS FGNPLATGDG
IRAGEKVGGS TELLDEAWWF PAIQWPDGRL QFMLNERMMP SQFVVNGAGK RFVNEAAPYM
DFAHAMIEGQ RSGVSHIPCW LITDIRSFRR YVIAGHLPIP KVPFAPVPTG RKVPRAWLQS
GVVHEGRSWE ELAGKIDVPA EALRRTAERF NELARRGHDD DFNRGDSAYD NYYGDPTLPN
PNLYPLTKPP YYAFQIILGD LGTSGGLRTD EYARVLRSDD SVVKGLYAVG NTAASVMGRS
YAGAGATIGP AMTFGYVAAK HIANEITTAA IESTSQRRC
//
