ID I0RQ19_MYCXE Unreviewed; 789 AA.
AC I0RQ19;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Polyketide synthase {ECO:0000313|EMBL:EID13222.1};
GN ORFNames=MXEN_11615 {ECO:0000313|EMBL:EID13222.1};
OS Mycobacterium xenopi RIVM700367.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1150591 {ECO:0000313|EMBL:EID13222.1, ECO:0000313|Proteomes:UP000003584};
RN [1] {ECO:0000313|EMBL:EID13222.1, ECO:0000313|Proteomes:UP000003584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RIVM700367 {ECO:0000313|EMBL:EID13222.1,
RC ECO:0000313|Proteomes:UP000003584};
RX PubMed=22628510; DOI=10.1128/JB.00482-12;
RA Abdallah A.M., Rashid M., Adroub S.A., Elabdalaoui H., Ali S.,
RA van Soolingen D., Bitter W., Pain A.;
RT "Complete Genome Sequence of Mycobacterium xenopi Type Strain RIVM700367.";
RL J. Bacteriol. 194:3282-3283(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EID13222.1}.
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DR EMBL; AJFI01000061; EID13222.1; -; Genomic_DNA.
DR AlphaFoldDB; I0RQ19; -.
DR PATRIC; fig|1150591.3.peg.2330; -.
DR Proteomes; UP000003584; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR CDD; cd05195; enoyl_red; 1.
DR CDD; cd08956; KR_3_FAS_SDR_x; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR013968; PKS_KR.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF51; PHENOLPHTHIOCEROL_PHTHIOCEROL POLYKETIDE SYNTHASE SUBUNIT E; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR Pfam; PF08659; KR; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SMART; SM00822; PKS_KR; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SMART; SM01294; PKS_PP_betabranch; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000003584};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 633..708
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 789 AA; 83626 MW; F9A3FCDD72BEB7F2 CRC64;
MVQIPRVHGC RAVAGLLVPP TDRPWRLGLT SAGTFENLTL EPIPEADAKL QPGQVRVATQ
AIAANFRDVM ITLGLYPDDD AVMGIEAAGI VVETGSDDCR FAVGDRVMGL FPEGTGTTAI
TDERLLMTIP DGWSHTDAAT VSVVFATAYY ALSRLADVKP GQRVLIHAAT GGVGMAAVQL
ARYWGLEVFA TASRGKWDTL RAMGFDESHI GDSRTLEFED KFRAVTGGRG MDVVLDSLAG
EFVDASLRLV APGGIFLEMG KTDIRDPNAV AQQHPGVRYR AFDLFEAGAD GIQRILTDLA
AMFAARVLHP LPVTGFDIRR APAALRYLSQ ARHVGKVVLT MPDVWAAGTV LITGGTGMAG
SAVARHVVAR HGVRHVVLLS RRGAEAPGVG ELVGELGGSG ATVRVVACDA ADREALAKVI
SDIPVQWPLS AVIHAAGVLD DAVVTSLTPQ RVDAVLRAKV DAAWNLHELT RDLGVSAFVM
FSSMAGLVGS SGQANYAAAN AFLDALAAHR RANGLPAMSL GWGLWEQASA MTGQLDDVDF
ARFARDGVVA MSSEEALQLF DTAMVVDQPF VLPARIDLAA LKAKFDAGTL PPMFVDLINA
PARRQVDDSL AAAKSKSALL QRLEGLPEDE QHAILLDLVR SNIATVLGNT TPEAIDPDKA
FQELGFDSLT AVEMRNRLKA ATGLALSPTL IFDYPNSAAL AGYFRQELLG GAQPKTQPVA
PGEAEIQRVV ASIPVKRLRQ AGVLDLLLAL ANETNGAATP DTPEETTAKN IAEMDLDDLV
NAALMDDDD
//
