ID   I0YIC5_COCSC            Unreviewed;       747 AA.
AC   I0YIC5;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Cullin {ECO:0000313|EMBL:EIE18144.1};
GN   ORFNames=COCSUDRAFT_38727 {ECO:0000313|EMBL:EIE18144.1};
OS   Coccomyxa subellipsoidea (strain C-169) (Green microalga).
OC   Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC   Trebouxiophyceae incertae sedis; Elliptochloris clade; Coccomyxa;
OC   Coccomyxa subellipsoidea.
OX   NCBI_TaxID=574566 {ECO:0000313|EMBL:EIE18144.1, ECO:0000313|Proteomes:UP000007264};
RN   [1] {ECO:0000313|EMBL:EIE18144.1, ECO:0000313|Proteomes:UP000007264}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C-169 {ECO:0000313|EMBL:EIE18144.1,
RC   ECO:0000313|Proteomes:UP000007264};
RX   PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39;
RA   Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D.,
RA   Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J., Proschold T.,
RA   Salamov A., Schmutz J., Weeks D., Yamada T., Claverie J.M., Grigoriev I.,
RA   Van Etten J., Lomsadze A., Borodovsky M.;
RT   "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea
RT   reveals traits of cold adaptation.";
RL   Genome Biol. 13:R39-R39(2012).
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EIE18144.1}.
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DR   EMBL; AGSI01000026; EIE18144.1; -; Genomic_DNA.
DR   RefSeq; XP_005642688.1; XM_005642631.1.
DR   AlphaFoldDB; I0YIC5; -.
DR   STRING; 574566.I0YIC5; -.
DR   GeneID; 17036148; -.
DR   KEGG; csl:COCSUDRAFT_38727; -.
DR   eggNOG; KOG2166; Eukaryota.
DR   OrthoDB; 21270at2759; -.
DR   Proteomes; UP000007264; Unassembled WGS sequence.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007264}.
FT   DOMAIN          392..622
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   REGION          325..344
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   747 AA;  87539 MW;  1EFB191D4803D2C5 CRC64;
     MQDRKPIELE AGWTFMQNGI MKLRKLLEGE EEEQFTAENY MMLYTTIYNM CTQKPPYDYS
     EQLYNRYKDS FSLYIREKVL PALREHHEEY LLRELYKRWG NHKVMVRWLS RFFNYLDRYY
     ITRHSLHSLN DVGLIRFRDD VYTEVKVQAR GAILALIERE REGEQVDRAL LKNVLGIFIE
     VGMGGMDCYA DDFEKQLLSD SAAHYKKKAT AWIAEDSCPD YMLKAEECLK AEEERVANYL
     HVDTKPKLLK EVETEILEHY ESELLEKDNS GAASLMRDDK KEDLARMYRL FQRIPKGLEP
     VAEIFKKHVE AEGMKLVKEV TEAIQSKKEK DAGKPSKDSG STHEQQYMKT VIELHDKYLQ
     YVVESFNNSS LFHKALKEAF ESFCNKTVAG ITSAELMANF CNTLLTRGGG GDKMTDDAVE
     EMLDKVVKLL AYISDKDLFA EFYRKRLSRR LLAERSASDD HERAVLTRLK QQCGAQFTSK
     MEGMVTDLQL AREKQQGFEA WQKENGKTIS IDMSVQVLTT GFWPQYKVVD LALPQEMVDG
     VSLFKEFYEA TVKHRRLQWY YHHGYANLRA NFRSKPIDIT TNTTQATVLL LFNADEKLSL
     QEIKERVNLP DEDIIRILHS ISCGKYRILA KEPNNKTINK ADIFTFNAAF TDRMRRIRLP
     APPSDERKKV VEDVDRDRRY SIDAAIVRTM KSRKILQHQQ LVLEVVQQLQ RMFQPDIRVI
     KKRIEDLINR EYLERDKDNP NTFRYMA
//