ID I0YKA7_COCSC Unreviewed; 843 AA.
AC I0YKA7;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 22-FEB-2023, entry version 31.
DE RecName: Full=tRNA/rRNA methyltransferase SpoU type domain-containing protein {ECO:0000259|Pfam:PF00588};
GN ORFNames=COCSUDRAFT_59757 {ECO:0000313|EMBL:EIE18826.1};
OS Coccomyxa subellipsoidea (strain C-169) (Green microalga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Trebouxiophyceae incertae sedis; Elliptochloris clade; Coccomyxa;
OC Coccomyxa subellipsoidea.
OX NCBI_TaxID=574566 {ECO:0000313|EMBL:EIE18826.1, ECO:0000313|Proteomes:UP000007264};
RN [1] {ECO:0000313|EMBL:EIE18826.1, ECO:0000313|Proteomes:UP000007264}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C-169 {ECO:0000313|EMBL:EIE18826.1,
RC ECO:0000313|Proteomes:UP000007264};
RX PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39;
RA Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D.,
RA Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J., Proschold T.,
RA Salamov A., Schmutz J., Weeks D., Yamada T., Claverie J.M., Grigoriev I.,
RA Van Etten J., Lomsadze A., Borodovsky M.;
RT "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea
RT reveals traits of cold adaptation.";
RL Genome Biol. 13:R39-R39(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIE18826.1}.
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DR EMBL; AGSI01000021; EIE18826.1; -; Genomic_DNA.
DR RefSeq; XP_005643370.1; XM_005643313.1.
DR AlphaFoldDB; I0YKA7; -.
DR STRING; 574566.I0YKA7; -.
DR GeneID; 17036776; -.
DR KEGG; csl:COCSUDRAFT_59757; -.
DR eggNOG; KOG0231; Eukaryota.
DR eggNOG; KOG0838; Eukaryota.
DR OrthoDB; 915574at2759; -.
DR Proteomes; UP000007264; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030488; P:tRNA methylation; IEA:InterPro.
DR CDD; cd18092; SpoU-like_TrmH; 1.
DR Gene3D; 3.40.1280.10; -; 1.
DR Gene3D; 2.20.110.10; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 2.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR003409; MORN.
DR InterPro; IPR001537; SpoU_MeTrfase.
DR InterPro; IPR033671; TrmH.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR PANTHER; PTHR43453; RRNA METHYLASE-LIKE; 1.
DR PANTHER; PTHR43453:SF1; SPOU_METHYLASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02493; MORN; 3.
DR Pfam; PF00588; SpoU_methylase; 1.
DR SMART; SM00698; MORN; 3.
DR SUPFAM; SSF75217; alpha/beta knot; 1.
DR SUPFAM; SSF82185; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007264};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022555};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 35..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 310..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 659..782
FT /note="tRNA/rRNA methyltransferase SpoU type"
FT /evidence="ECO:0000259|Pfam:PF00588"
FT REGION 490..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 541..604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 586..600
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 843 AA; 88332 MW; 6B6E3CC1D90198E2 CRC64;
MFHETIRSLV QAGVLLAAGA FANNLGSLEK IDAQLGLKFA AYVTLPALAL QLLSVPGVAG
IQALTIVSVS AAFSAFLALL GWLVHGKRRG PERALLTGSA VGVALGTFGL PFVEAAFGTA
GVRIALLWDL ANVVAVCGLA YLVFASGGSP PPALYEHADG GTYRGQWRGN KKQGLGVYVY
PGGGRYEGMW RDNVKHGYGV YAFPKGGLYE GEWVAGEREG MGARLMRNGS IKAGRWGTAK
LEKQMDPLDC AYAVNAAQRA AQAARRVKVG GGKVEDVLMN LAMQPFVWAS AAALWLSYSG
SPLPALVDAV SGTLASAHLP LVLLCSGALL AAPHPKVLQV KDTAAVLLTR YVSPLLLAAA
AALVSPSHSL LAAVAAICAL SPAPYALVDY AREARLNDSF AAALAPLSSM TSAILMALLA
LLVSSQVPPP LTTAEAALPP LVPPVPFAAA AAALAAAVSV AAFLYVRLAG RTRRGSGNNP
PRGAVRMTLQ ATPSQPMPPV TILEPPSQEV TPAQEAASDA DVSEGEPAES FVGQLGVDDS
AADVSAEPDE AAQQERPGAQ RAEAASSAEE ATSSNENSGG ADQSRGRGRR PGRGMFRDVD
EDNPGGLAAS AVVRRGFDVG GCEASSSLIL EALIPQVLPE RLERIQQVAS DRCHSILPVV
EALGFGAVQC IDSSVERVKS ARGNRTSKGA EKWLDVQRTW GTRRCVEYLR DCGYRILVTQ
PTADSVPIGA IDWTLPTAFI LGNEVNGASA EAIELADQAV TVPMAHSFTE SFNVSVAAAL
ILSEARRQRL EKLGRCGDLS PEETQTLTAI MLLKHRGGNA LSWHPHWKQH AQRIDQQALS
YAM
//
