ID I0YRD2_COCSC Unreviewed; 916 AA.
AC I0YRD2;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Glucosidase II subunit alpha {ECO:0000256|ARBA:ARBA00042895};
GN ORFNames=COCSUDRAFT_67320 {ECO:0000313|EMBL:EIE20951.1};
OS Coccomyxa subellipsoidea (strain C-169) (Green microalga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Trebouxiophyceae incertae sedis; Elliptochloris clade; Coccomyxa;
OC Coccomyxa subellipsoidea.
OX NCBI_TaxID=574566 {ECO:0000313|EMBL:EIE20951.1, ECO:0000313|Proteomes:UP000007264};
RN [1] {ECO:0000313|EMBL:EIE20951.1, ECO:0000313|Proteomes:UP000007264}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C-169 {ECO:0000313|EMBL:EIE20951.1,
RC ECO:0000313|Proteomes:UP000007264};
RX PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39;
RA Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D.,
RA Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J., Proschold T.,
RA Salamov A., Schmutz J., Weeks D., Yamada T., Claverie J.M., Grigoriev I.,
RA Van Etten J., Lomsadze A., Borodovsky M.;
RT "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea
RT reveals traits of cold adaptation.";
RL Genome Biol. 13:R39-R39(2012).
CC -!- PATHWAY: Glycan metabolism; N-glycan metabolism.
CC {ECO:0000256|ARBA:ARBA00004833}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 31 family.
CC {ECO:0000256|ARBA:ARBA00007806, ECO:0000256|RuleBase:RU361185}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIE20951.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGSI01000014; EIE20951.1; -; Genomic_DNA.
DR RefSeq; XP_005645495.1; XM_005645438.1.
DR AlphaFoldDB; I0YRD2; -.
DR STRING; 574566.I0YRD2; -.
DR GeneID; 17038930; -.
DR KEGG; csl:COCSUDRAFT_67320; -.
DR eggNOG; KOG1066; Eukaryota.
DR OrthoDB; 5480935at2759; -.
DR Proteomes; UP000007264; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06603; GH31_GANC_GANAB_alpha; 1.
DR CDD; cd14752; GH31_N; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1760; glycosyl hydrolase (family 31); 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 2.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR030458; Glyco_hydro_31_AS.
DR InterPro; IPR048395; Glyco_hydro_31_C.
DR InterPro; IPR025887; Glyco_hydro_31_N_dom.
DR InterPro; IPR000322; Glyco_hydro_31_TIM.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR22762; ALPHA-GLUCOSIDASE; 1.
DR PANTHER; PTHR22762:SF54; BCDNA.GH04962; 1.
DR Pfam; PF13802; Gal_mutarotas_2; 1.
DR Pfam; PF01055; Glyco_hydro_31_2nd; 1.
DR Pfam; PF21365; Glyco_hydro_31_3rd; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
DR PROSITE; PS00129; GLYCOSYL_HYDROL_F31_1; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361185};
KW Hydrolase {ECO:0000256|RuleBase:RU361185, ECO:0000313|EMBL:EIE20951.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007264};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..36
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 37..916
FT /note="Glucosidase II subunit alpha"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003636317"
FT DOMAIN 111..297
FT /note="Glycoside hydrolase family 31 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13802"
FT DOMAIN 341..673
FT /note="Glycoside hydrolase family 31 TIM barrel"
FT /evidence="ECO:0000259|Pfam:PF01055"
FT DOMAIN 681..770
FT /note="Glycosyl hydrolase family 31 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21365"
SQ SEQUENCE 916 AA; 102866 MW; FB02BD3D75D39996 CRC64;
MGEEMINPSR KGNHSFLTSF FLIFLFSSLQ FQLSTSVKVE DFKKCTDAAF CNRLLGTRDE
GYYIDPASVQ FSGPSVTARL LNKAKGTDVT LTMKAYKGFV RLLVNEDASK KRFEVPGVLM
HDLGSREAIW SKKAQTAQSL LLQLEDAEMQ LQYSPFQIGI SIKGKPVMSF NGRQMFNFEH
LRQKQEGDPE GWWEETFKGH VDSKPRGPEA ISFDLEFPDT QHVYGLPEHA TSLSLNPTVD
LADNATSEPY RLYNLDVFEY APESPFGLYG SIPFLWAQKL GVAVGAFWLN AAEMYVDVGK
TEEGTFTNWV AESGILDLFL LLGPTPAKVS EQYAQITGAT ALPQYFALGY HQCRWNYRDE
ADVRQVDAGF DAYDIPYDVI WLDIEHTDGK RYFTWDKSLF PDPVKLQEDV ASHGRKVVTI
IDPHIKRDPG YYIYQEAEQN HYFVRDKDGK DFDGWCWPGS SSYLDMLNPE VRAWWAQQFA
LSKYKGSTPN LYVWNDMNEP SVFTGPEITM QKDNLHWREV EHRNLHNLYG ALFHQGTAEG
LIERGKAVYG SDADRPFVLS RAFFAGTQRV GPIWTGDNCA DWKHLRVSLP MIMSVGIAGL
PFNGADVGGF FGNPDAELQT RWNQVATFYP FFRGHAHLDA KRREPWLFGE DATRRIRDAI
RARYVLLPYI YTLFRHANTT GLPVMRPLWY EFPEVEATHG VDDEFMLGPA LLVSPVLEEG
AESRAVFLPG KGPWYSARTG EPVKPDAGGA LTVPVTMDSV PSYLRGGHIM PLRERARRST
AAARKDPYTL LVALDSEGQA SGDLYLDDGS SFAYKRGLFA HRLFSFKDGM LSNQELPGNP
SPPRYSTDLV IERIIIVGLG HPAKSFSVKE VGTGKVLQTG AGPVVQEAGV PELALVIRKP
ELPVTGDWSI QLSVTA
//
