ID I0YTB1_COCSC Unreviewed; 2769 AA.
AC I0YTB1;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN ORFNames=COCSUDRAFT_56833 {ECO:0000313|EMBL:EIE21630.1};
OS Coccomyxa subellipsoidea (strain C-169) (Green microalga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Trebouxiophyceae incertae sedis; Elliptochloris clade; Coccomyxa;
OC Coccomyxa subellipsoidea.
OX NCBI_TaxID=574566 {ECO:0000313|EMBL:EIE21630.1, ECO:0000313|Proteomes:UP000007264};
RN [1] {ECO:0000313|EMBL:EIE21630.1, ECO:0000313|Proteomes:UP000007264}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C-169 {ECO:0000313|EMBL:EIE21630.1,
RC ECO:0000313|Proteomes:UP000007264};
RX PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39;
RA Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D.,
RA Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J., Proschold T.,
RA Salamov A., Schmutz J., Weeks D., Yamada T., Claverie J.M., Grigoriev I.,
RA Van Etten J., Lomsadze A., Borodovsky M.;
RT "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea
RT reveals traits of cold adaptation.";
RL Genome Biol. 13:R39-R39(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIE21630.1}.
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DR EMBL; AGSI01000012; EIE21630.1; -; Genomic_DNA.
DR RefSeq; XP_005646174.1; XM_005646117.1.
DR STRING; 574566.I0YTB1; -.
DR GeneID; 17039614; -.
DR KEGG; csl:COCSUDRAFT_56833; -.
DR eggNOG; ENOG502QPPT; Eukaryota.
DR OrthoDB; 316075at2759; -.
DR Proteomes; UP000007264; Unassembled WGS sequence.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 2.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 2.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 2.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007264}.
FT DOMAIN 157..228
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT DOMAIN 1123..1194
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT REGION 49..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 126..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 263..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 842..874
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 906..948
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1518..1573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1677..1724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1774..1870
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1893..1934
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1949..1981
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2043..2071
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..66
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..305
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..435
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 441..456
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 917..936
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1518..1540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1550..1573
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1687..1724
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1775..1807
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1830..1844
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1893..1915
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1916..1931
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2769 AA; 298965 MW; 66C911166A01351D CRC64;
MAEVTAATTR TVAKLQQGQD KIKVMHFSDE HHAHQIAAGS VLNLWEERKA QERTQAEDRR
RKSSLGSDGD AQQAAQGAAQ RPPKTGRQRR SSSRIQLWAE ARIPLTSRLS PSNSGKNIQV
ELAPATADHG DKTQGSTAAG PAPEQEQVPC MTQYQGAVLI ADITGFTALT EDLGRRGTAG
VELLTRCMNN FFTLVIQTVV VHGGDVMRFA GDSMICAFLP TPKEAASHDQ GLAAATLRSV
QCAWALAESL GSMRMLMDGK VAPVPKTERV QPQMPSRGSV DRGSDSTPLW RRTLRMSTDT
QPRSNALEAF DRHSKRGEAL GSQGASQPSR EGPSGWRARH LSLSSSQGAS QSIEKSDDLR
RAQSSCSSAT SSAASIGSLP SGTSSQRQAA QTRQRSNSAG MTGMLQRLVS SRRASGHGTQ
DSSSPFDSPT PWQSPRVSDH YEAHSPVRHR SEGEDTQTGT VHVISKGSPI VPRPRGLSEG
TEGSQLRVSR LHPDGAPASP FIKRSLPVAS VVRAPSEPPS APEAAAESSA KQKLAPGLHS
LAASKKQAEP EESFGGVPLE AYFRQTSIAA HRPPHIPVMR TVAEVNSEDP GLAPVSSLET
ASSVGSIASN MANVPSLDVK WDVTTSKFVS SAPGSLSHRE ISQFVKQRLE GPAPGAQDIA
LLVDTAVGDR IRTQLRTLYK DSLNIRKAER IAAARASLMS MPESKRAKIN PFRSDNSLSL
GARSGSFGTD VPKIQKRTSV QLVGPIVKEA SLAIEPALPR PKAPEPSHLL AEMEPLTRWG
PGPVAESISD DKEVPPVSSM AAVDEVPTEQ IAEAPTAAAG SRRATRASGG WGFDWLLKRR
SKDRASRVKS RGSLMPRRWS SVQMNKSKED RRSSLPVLRT ARRVSNYAAL RERRWSTAVW
KSLLPTRKER PDSANASRRE TQNQDTSASR QNIGSKRPPR SPPPRVSNHT LSLKVAVGCG
NICAFHVGGT AETESSLGRW EFFIGDHPHL SEGDGERQPV EQISLVEGFL EAGEVGLSAE
VIAQGLATEG EAKSDGFEDF MNLGKDVRAS ALDVLRMHLP DSLAQRIEAG HLAFINEIRR
PTTSSMDPIT SVQAAIEVVQ RIMKQHEGSF LQLRCDEKGF LSICAFGLPG KAHEDDPSRG
IRAAIDIVNS LEKIQEEGVV GVTTGQLLCA CVGSDLRSEY TVYGDAVNLR ARLMVKAASG
LGSVLCDYTT HQLGAGAAAF VKPEPIKVKG KAFPLDVFIA APKAQDFDMA SMTEQQLQPQ
AKLSSSKLAL FGVAATARHR PIIGAENALA KIYGRVDSLV EAAEGGCILI EGDAGMGKSR
LMEEIQRSNL GGNRDAITML FSSADFDHRG QAMYPWRRVF KGLFQHDRAH GQLYSMRRRD
GRGRPMVVSK LGKRLADAEA DWRHWTKSLA GLLEVLEDEM PTLPAANAQV SVEPGIKAGP
KRQRKSLAHA VPLLGHPSKS MPMMQQQSMP IFKMPDSAKP IGNPFAGFAE TAVTRLDSYQ
KQTSQRTVSD LLAETVSSSM HRSASQGALE GRSTSLQKAQ EAEPIDVREG SNSTPINPDQ
YAQSKGMQTP DRSALQGSIA RYASGMKSRM SQRPLPTGAD AVQMPSLWSR EVSKSPMPSV
STPRVPQKSA LHGALANLLR GQKGLRDAKR AAALMAQPPL TQQNSLANIA SNMKAASGEA
LSRAHSRQAA AEQQPSQPQQ QLRGHSASRQ PVQASAFSTT GLSVHSRDSS CSGFNFFGGA
NSSPGSSEAG GPRTAGILNF SAATLQRPPV LDMSAATSRR TSDSSMASST RVSQSGAPPQ
PHLARSSSSP APVPAAARSD ELASSAPRRR TLQGEDEGSL ERTLHMGFHS RQALTPIRSG
EVESFKRPTQ SWQPLRSAFG DAALHETIDV VSWPSESEVS TACPSPANRS SRLSDTAGKL
QHKRSGDGGP LERIKRMCSS PLVGHMLGRL ASGALPKARR PRGLSDTKTN PDGGPETPAS
IETGELQLGF SAPAGLHEAC DAAIAALSMQ QAPPQPKSML RKASRSTFGS LFLRKQQSSA
LQPWHSPLPD VMPHVPSQTQ GSGSAARMKG PQGLLSRAAL REALTSSPNA FASARNNESL
HSQEDLRQMS SPFLTFATFQ QQADIKASKF GQVLRTRSTS LDSMAGSRTS GRGLRRSETT
INVDHSHTLG GMPHAKELLI LALREWTKVY GPLVVLLENF DRADALSWSL LSRCAEEIDM
PVMVIVAVRP NDGVFASPLP GQAAKAALHA KMSTLLEDIR ENPFTLRMVL QPFTPEHTQA
FLNAALDGVL VSSDVAHNLW EKTGGLPLYI EQHNLWEKIG GMPLYIEQMV VYMQQHQAGR
EGAVEQADLS AFIRNTVTIH SLITDRVDRL RPSQQLTLKV ASVMGMSVSL DLLLDMYPIA
TSREALQRDL IDLEAARFLR ATDVPGTWMM TQVLARDVAY ELIPFSQRRA LHADLARALE
EDGRAGCVPA TILAYHWTHS CAGVEAGEWR RALQAVWWWE RAAHAAQEEG IDPSEALRLF
QRADEIAAVL KASYRARSQT QLGHKSLWPG HTRPSSHLVG PSFRSSGWSS MVVHPVRRAQ
WQRCMAACGL ALGDLDNARR HALQALHHLG APLPSDPSRR SFVLRSWLAL GPLGCLSGPA
NRRVSADGSD EVDISLVGDF AAWVEESATG SGQTPLEGTV DDTEEDWQGK RMQEAARVLG
LLVKASLMLT PVDVDALKYI CATAASLQGK RIWGRVPQTS LLYPVMSECR AALLEASPQQ
HRSRFFRLK
//
