ID I0YYM2_COCSC Unreviewed; 4273 AA.
AC I0YYM2;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EIE23491.1};
GN ORFNames=COCSUDRAFT_65942 {ECO:0000313|EMBL:EIE23491.1};
OS Coccomyxa subellipsoidea (strain C-169) (Green microalga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Trebouxiophyceae incertae sedis; Elliptochloris clade; Coccomyxa;
OC Coccomyxa subellipsoidea.
OX NCBI_TaxID=574566 {ECO:0000313|EMBL:EIE23491.1, ECO:0000313|Proteomes:UP000007264};
RN [1] {ECO:0000313|EMBL:EIE23491.1, ECO:0000313|Proteomes:UP000007264}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C-169 {ECO:0000313|EMBL:EIE23491.1,
RC ECO:0000313|Proteomes:UP000007264};
RX PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39;
RA Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D.,
RA Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J., Proschold T.,
RA Salamov A., Schmutz J., Weeks D., Yamada T., Claverie J.M., Grigoriev I.,
RA Van Etten J., Lomsadze A., Borodovsky M.;
RT "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea
RT reveals traits of cold adaptation.";
RL Genome Biol. 13:R39-R39(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIE23491.1}.
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DR EMBL; AGSI01000007; EIE23491.1; -; Genomic_DNA.
DR RefSeq; XP_005648035.1; XM_005647978.1.
DR STRING; 574566.I0YYM2; -.
DR GeneID; 17041483; -.
DR KEGG; csl:COCSUDRAFT_65942; -.
DR eggNOG; KOG0889; Eukaryota.
DR OrthoDB; 3666795at2759; -.
DR Proteomes; UP000007264; Unassembled WGS sequence.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd05163; PIKK_TRRAP; 1.
DR Gene3D; 1.10.1070.11; Phosphatidylinositol 3-/4-kinase, catalytic domain; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003152; FATC_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR036940; PI3/4_kinase_cat_sf.
DR InterPro; IPR003151; PIK-rel_kinase_FAT.
DR InterPro; IPR014009; PIK_FAT.
DR InterPro; IPR046807; Tra1_central.
DR InterPro; IPR046805; Tra1_ring.
DR PANTHER; PTHR11139; ATAXIA TELANGIECTASIA MUTATED ATM -RELATED; 1.
DR PANTHER; PTHR11139:SF1; TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN; 1.
DR Pfam; PF02259; FAT; 1.
DR Pfam; PF02260; FATC; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR Pfam; PF20175; Tra1_central; 2.
DR Pfam; PF20206; Tra1_ring; 2.
DR SMART; SM01343; FATC; 1.
DR SMART; SM00146; PI3Kc; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51189; FAT; 1.
DR PROSITE; PS51190; FATC; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007264}.
FT DOMAIN 3120..3632
FT /note="FAT"
FT /evidence="ECO:0000259|PROSITE:PS51189"
FT DOMAIN 3915..4240
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
FT DOMAIN 4237..4273
FT /note="FATC"
FT /evidence="ECO:0000259|PROSITE:PS51190"
FT REGION 419..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1097..1168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1263..1382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2160..2242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2497..2520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2754..2935
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2948..2983
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3649..3749
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1360..1379
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2175..2207
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2209..2231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2754..2773
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2799..2813
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2852..2875
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3649..3672
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4273 AA; 468019 MW; B284FF0B5AE00E4C CRC64;
MTKMLASSDF EGLAQALQAP DAGVEQQLAR MTEIRESIEL VHTQEYGKLP HNDFLRPHAV
VLMQAALNVL NTDNEENGLL CLRITFDLHK AFRPNLEELV FEGVSASYKN YFEPGPEGRQ
MQDIIPTTQS FKIVAETPIQ VMFLINLYSR SVNQYVPVLA PLMVNAVSLP GLPAAVQQDN
KLKALASDFR NAQVKILSFL TYLLRQFPGV IRPHQESIST SLVRALQACP DSVQMRRELL
IATRHVLTTS VRGGFLGELE TLLKEETLVG RGRQCQTELR PLAFSMLAEL VHHVRSDLTF
AHLSRVIYLF CRRAPAPRCS KWAFPFELWQ MNLHDSTLPV SVECTSVRLL LNLVEVVFAR
RADVRSAEAH RQLLAGILDA FTSKLSSLHH RLPLLLSYVA EREALQVKAE AEAKASEAAA
ASAGDAAPAQ AAPPADQPQG AAPATAAAAA AFPAPEGGQG AAAGVPKAQD SQADAAKQSI
PAKPPEVPRL KVLYIQERSE HDKQVSDAKL ILSTLIMGMK TLLYSITNYG NTIVSSQPGT
PQLPSMGLRE AEIRLATRTI KRGLPCLQLY GDRAGQEPRV YDRHADIYDT FADMFTVLTN
PRDVIEVFSL QMPRFFDAII ENPRLLRVVG TLFASPPIGP PFAQEGELTL KLLNLFLDAL
TKFPGLEGVL APFFHELVSK TLARLHNSTA KEGYLDLLLA LFRAISMLRQ QGGAVVNGVA
SGESLCALFT GSGVGVTNPP LLVPTIDHLT ALLEGPRSGP YKSALLELLL IMPCRLSEIL
SVLGRLMAPL VAALSGNEAL VTLSIRTLEY WVDSLNPEFL EPAMLPVIPQ LMRALWSHLR
PLPYNFSAKA LALLGKLGGR NRRFLKDPLE LDLKDNPEHG LRLILTFQPS TSFLVPLDRC
LALSSQSLLA PTSKQSVHEK REALRFLHIC LASVLNLRSP DDSELPGTSM DKLTSMLFGN
QAPPHIEPTP AVTEMGVKTK TQLLAERQVL RQLITSVIAA SADKDLQPQG ADYTLGVCRH
FALLFAAGAS APLPSVPAGT ETSRTARMSS LKELDPHIFL DALVEVLSEE DADRVDAAVK
GIEAFVDTLM LVTETQNELS KAGGPEEASA ADDVSPAEPM NVDAASPAQE TTAAGAATEN
GTADPAAQKE TTPRPGSPKR PTVSSAEGSW PASLDELLAR VLHCCYGDSW ATRIGGLAAV
GLLAKKLPAV QLRARLPLCV RALLTVMRGL PEHAISQVQE LRATLTGLLH RCLIEGRPLP
TPAEVKASSQ RVGAEGTSVT EGTSAVEAKD EAAGAGQDTP MPNAKEPEQP AAAAPAPTAA
ADVAPAAAGE QPPISLPRMS SSVSAEMAIS PGGAAAEDIS PRGSKEESAA DKAPSMEPLD
EGTDRTLAGV VQVVSHELLS PRSSEALRKL ADECLKASPN HSRLPAAVVC KASGRTSAQL
LKPLLEKLSP PLEKRRLMPL KHANLQIGNA AAFTYCMQQK PPLLPLSQEV VMVISDAYVL
SEMDDANLTA QLAGLQRVSG DTTKVADQLR SVCLSMLCAA MQWDDFRDSG DLAELRGRII
QIFFKHLTSS NEVAVCMSQE GLSAVIAHQK MPKHLLQTSL RPILVNLAYY NKLKLPLLRG
LARLLNLLAS WFNVTLGEKL IDHLKKWLEP EKLLQVTHSW EPGQECHIAA AILDLFHLLP
PPAVKFLESG ERPGLVVLMI ELEGALAQMP SNTEPTKMWS PYREPLARFL NKYPEEAVTY
FLERKRMANP SYIHRFIDIL RSPLGQPLLS QLAASSDKLA ELINFPFVAP PPPEQLTPEQ
IQDEKAKVAA HFHAVHLIAI VTKLLPEWLP QPLFELLLHQ VEDEERLERA QLYESKRLAK
ALLSYLSRHH DLVGPLFDLL DIFTVRTRVD FAFLKDYLKT TILRHFLEVF QQQSRPQEQL
VQAASLLVLP MLEAGYEAGK AIVDDDALTT MVTIMFDPPD DLASAYGEGM KMELLQLATL
LIRRAPQQLV QHRKELIKFG WNHLKRDDSA AKYYAFLNVC HFLDAYQAPE KIVLQVFVAL
LRTCQPDGRR VLVRQALDTL TPALVRRLAP GDAKYPIWVR YTKKVLVEEG HSMPHLIHIW
QLIVRHADLF YSSRTQFMTQ MVNGLMKLGL PQNATLENRR LSLDLAGLVV HWEQRRIAES
EAAPTAAADA SQAEPISLKR RREGGSGIPT EIKEEVEAAE EGRPAKQPRT EGTPSNGQAA
PDQQAAQQPA GPEASGSAGA AANAAAEAQV LADVDPSLAQ ARQASSSADE DCKLTPTMQE
MVLVFLIRMA FLLGDGHKEA EYQTLHKHTL ALFGEALSLW PNVPIKINFI NKLLESNIAH
NQDPPPALVT GLKLMKQALV VQPTLFMQVS HQALIYVLEP AFTSSHNTVV SLLCDMLERL
YKEFYTVPKT NEPPPTIPPQ VSEVNHRVHE IMQHHLTQAY NQNVPLTPAS PAGLLGVCAS
LRVLSTLEAF APDYVARFTP LLVKLLNRVA RDHASPGGLV LDPTRQPLGR SPREGGDMGE
PEYGTLTWAT LAALKLAANK VLMQADRKKL FLQTLVLLIT GNAAKHTDPA ILMGILTIVR
SWLLNPQPHS AAPNKPPELV SLTEKEAILF LQRLASLARN GWTRGPLQQR WESTFLEMIH
SLCTSTNLGD GLRVDVFDKV ERVFLLGLRA SDPAMRRKFF DLYNSAIPVT LFDRLRFIVC
SQDWEHLADT FWLKQGLDLV LAVLVEKEPI KLAPNSAQIP ALLAQTKQNI FHLKPHQSPA
PQQQQQQQQP PALQAAIAAP PGGQPAADGA VAAPVENSDM PASTAQQPPA PDASQAVPKT
EPGTDLQQQG QPMDVDPKPE EAGQQAGAMA APPVPQPLPG QIPPPAAPHA LPGPKMEPGA
PAAVGARPSE AAAQQPNGAL PGPVVPIAAH AHAGASGSGE MAPPPPVPQG LPKTQSGAIQ
LPTLLSMQSG LSTTGGNAGI QLPQWPQPPG PPPDGADAAE RPAEVAAQGI EEPKVPAGPM
LREATSGLAI PEAVDELMRE HLRFLYKEGS YEVQDMVSTV TEVAHGDAHM ACHLWVLVFP
IVWATLSEKK EQQIQLAKPI IALLSKEYHL RQAQQRPNVV QALLEGISLS QPQPKIPSEL
IKFLGKTYNA WHIAIPLLES HVMLFPTETR CFDALAELYS MLNEEDVLFG LWKRRGAAEE
TRAALSCIQH GVLQQGQDYL LDAIRKAANN QFPPLSADGR GVPSKGEQAQ WTKQYLACAA
ELSQWEVVAE YASVTENYAQ MAECLWRLHD WMRLKDIVLP KANVEDTPQS EMIRTYVKLQ
EGDIIEGDKH TSAGIGKALE KWWQLPEVGV WPQLQQLACF QRLDILETWR LRTPNEWEPL
GTWADVLNWR NAIYNVVINA FKNVGDMAPH LHQLGYRDKA WSVNRLAAIA RKHDCPEVCK
NIIATQYGFN AMEVQEAFVK IREQAQAFLE QPDQLIAGLN LLSGQNLDYF QTPHQAELFR
LEGLFHRALN DPEAANRAFS TSLSLWPQLA AGWLSWGDFC DSRAKANGSE ASWLENAVVC
YMQAIRHGSA PARAMMPRIL TLFSFHDSTG AVTQAIRKNS RQVPLNVWLP WLPQLQTSLQ
RPEAALVKDL LAQLATTYPQ AVYYGLRTIL LSLREAAVKA VQEVRQAART SSGAMPATPS
LLADQPSASA ASTGALPGGG PTASLSSGGA GGAVSGAGQA ANGMDTDSAA REVRSSGNVV
DSEAPAGEGA RAADGSSPSG QAAKPLEKPP EVVAFEAGKE IMDLLRSKHP HSTGSLELMM
SEIGTRFVPK AEERLLAVVH ALLHRCYKMP FSNNAEVPAS LKKELSGVCK ACFSNEHMAR
HGRLMGEYRD QFVRDLDPAS PGWPATLGEL SGRLKQWRAT LQSTEQAFTD VEMPGQYLGG
AEVAPESVVF LERIGSNVGI VRRHATSYRR LALHGSDGKT VHFLVQTGQH WSNTSGAADE
RMMQLLRNMN RLLDKHPQSR RRHLAWHTPI IVPVYPQVRL VEEELSYCSY GEAYEVNCAR
YGREADMPIA HFKKRCCSPS GNLISDPNGE IRLQAYHEIE TRLVTETVFS QYMYKTLPTS
NHLWAFKKQF CTQMALSGLL SHMLLIGGRT PYKILFARAS GKTFQIDFYP VYDQRGMLER
SEPVPFRLTR NLHTFFTPFG IEGVFVSAMA AAAQAVLGPN NNLADLLALF FRDDITAWSQ
RRQQRGGAWR HPQLKQLVDH NIDQCLKRMG HVAPSRPQEG VPASVQRGAQ ELVESALNPR
NLCRMDPTWH PWF
//
