ID   I0Z0L4_COCSC            Unreviewed;       434 AA.
AC   I0Z0L4;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=alanine--glyoxylate transaminase {ECO:0000256|ARBA:ARBA00013049};
DE            EC=2.6.1.44 {ECO:0000256|ARBA:ARBA00013049};
GN   ORFNames=COCSUDRAFT_53254 {ECO:0000313|EMBL:EIE24183.1};
OS   Coccomyxa subellipsoidea (strain C-169) (Green microalga).
OC   Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC   Trebouxiophyceae incertae sedis; Elliptochloris clade; Coccomyxa;
OC   Coccomyxa subellipsoidea.
OX   NCBI_TaxID=574566 {ECO:0000313|EMBL:EIE24183.1, ECO:0000313|Proteomes:UP000007264};
RN   [1] {ECO:0000313|EMBL:EIE24183.1, ECO:0000313|Proteomes:UP000007264}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C-169 {ECO:0000313|EMBL:EIE24183.1,
RC   ECO:0000313|Proteomes:UP000007264};
RX   PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39;
RA   Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D.,
RA   Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J., Proschold T.,
RA   Salamov A., Schmutz J., Weeks D., Yamada T., Claverie J.M., Grigoriev I.,
RA   Van Etten J., Lomsadze A., Borodovsky M.;
RT   "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea
RT   reveals traits of cold adaptation.";
RL   Genome Biol. 13:R39-R39(2012).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|PIRSR:PIRSR000524-50, ECO:0000256|RuleBase:RU004504};
CC   -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|ARBA:ARBA00009236,
CC       ECO:0000256|RuleBase:RU004075}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EIE24183.1}.
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DR   EMBL; AGSI01000006; EIE24183.1; -; Genomic_DNA.
DR   RefSeq; XP_005648727.1; XM_005648670.1.
DR   AlphaFoldDB; I0Z0L4; -.
DR   STRING; 574566.I0Z0L4; -.
DR   GeneID; 17042181; -.
DR   KEGG; csl:COCSUDRAFT_53254; -.
DR   eggNOG; KOG2862; Eukaryota.
DR   OrthoDB; 1010571at2759; -.
DR   Proteomes; UP000007264; Unassembled WGS sequence.
DR   GO; GO:0008453; F:alanine-glyoxylate transaminase activity; IEA:UniProtKB-EC.
DR   CDD; cd06451; AGAT_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000192; Aminotrans_V_dom.
DR   InterPro; IPR020578; Aminotrans_V_PyrdxlP_BS.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   InterPro; IPR024169; SP_NH2Trfase/AEP_transaminase.
DR   PANTHER; PTHR21152:SF24; ALANINE--GLYOXYLATE AMINOTRANSFERASE 1; 1.
DR   PANTHER; PTHR21152; AMINOTRANSFERASE CLASS V; 1.
DR   Pfam; PF00266; Aminotran_5; 1.
DR   PIRSF; PIRSF000524; SPT; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00595; AA_TRANSFER_CLASS_5; 1.
PE   3: Inferred from homology;
KW   Aminotransferase {ECO:0000313|EMBL:EIE24183.1};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR000524-50};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007264};
KW   Transferase {ECO:0000313|EMBL:EIE24183.1}.
FT   DOMAIN          84..324
FT                   /note="Aminotransferase class V"
FT                   /evidence="ECO:0000259|Pfam:PF00266"
FT   BINDING         380
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000524-1"
FT   MOD_RES         235
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000524-50"
SQ   SEQUENCE   434 AA;  47368 MW;  0D05BAF6A615762E CRC64;
     MRRKVAQAVA SSLWKTPATI SERANTYIRT FAAAPYSYTP PGRNHLAVPG PVNIHEQVMR
     AMDRPSQNHR DPWFPPFFQQ ILEDTKYIFK TTEGTPFIFP GTGTGGWEVA LTNTLSPGDK
     VVTFRYGQFS HLWIDMMQRL GLDVQVVEVE WGGGADEAKL EQILKADTDK KIKAVAVVHN
     ETTTGVTSDI GQVRQVMDSV SHPALLLVDG VSSIGALDFR FDEWKVDAAV TGSQKALSLP
     TGLGLVAVSQ KALEARKTAQ LKRVYYDLED QLATNPSGNV PYTPSIPLLY GLRETLGLIK
     AEGMDNVIAR HHRLAEGTRK AVEGWGLKLL CKEPRWNSDS LTVIKTPEGV DSGKIVKEAY
     SRYNLSLGVG LSEVAGKVFR IGHLGNNDEV MVGSYLFGAE MAMISAGVPI EPGSGVSKAI
     EYWAATSNVI PTRG
//