ID I0Z677_COCSC Unreviewed; 1278 AA.
AC I0Z677;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=PXA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=COCSUDRAFT_61136 {ECO:0000313|EMBL:EIE26146.1};
OS Coccomyxa subellipsoidea (strain C-169) (Green microalga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Trebouxiophyceae incertae sedis; Elliptochloris clade; Coccomyxa;
OC Coccomyxa subellipsoidea.
OX NCBI_TaxID=574566 {ECO:0000313|EMBL:EIE26146.1, ECO:0000313|Proteomes:UP000007264};
RN [1] {ECO:0000313|EMBL:EIE26146.1, ECO:0000313|Proteomes:UP000007264}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C-169 {ECO:0000313|EMBL:EIE26146.1,
RC ECO:0000313|Proteomes:UP000007264};
RX PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39;
RA Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D.,
RA Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J., Proschold T.,
RA Salamov A., Schmutz J., Weeks D., Yamada T., Claverie J.M., Grigoriev I.,
RA Van Etten J., Lomsadze A., Borodovsky M.;
RT "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea
RT reveals traits of cold adaptation.";
RL Genome Biol. 13:R39-R39(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EIE26146.1}.
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DR EMBL; AGSI01000003; EIE26146.1; -; Genomic_DNA.
DR RefSeq; XP_005650690.1; XM_005650633.1.
DR AlphaFoldDB; I0Z677; -.
DR STRING; 574566.I0Z677; -.
DR GeneID; 17044150; -.
DR KEGG; csl:COCSUDRAFT_61136; -.
DR eggNOG; KOG2101; Eukaryota.
DR OrthoDB; 2899602at2759; -.
DR Proteomes; UP000007264; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22999; PX SERINE/THREONINE KINASE PXK; 1.
DR PANTHER; PTHR22999:SF23; SORTING NEXIN-16; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007264};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 112..306
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 558..669
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 84..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 362..522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 749..790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 824..846
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 868..1011
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1242..1278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..422
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 436..463
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 868..979
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 980..999
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1251..1266
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1278 AA; 139466 MW; 89E1497E3B0A5258 CRC64;
MKTPLDATYV VERSIHQLVK FLFLSFILAL ALTHTSKSLW LNVPLALAAV AGLYWLSLQV
EIRARSNGTS AFYRRGRKES EEFGSEGATY TASVPPPASN KSDTKWREQV GSPVVEHAWE
TLCGSIIQEF VYDTWYAVLT PDREFPREIR RILNTAFGEL AGRARRADVR KMLLGDVSAL
FMEQIMLYRD TRDSILAGLD HDAWRVMPLE ARERALQAEM KADCNLHPAL YPPSPDGSAT
LGHYKVMRHI SEGLVAFMLE RHDHAKPILR SVARELLSSC VLRCLMFFFN PYTANKLILS
LLREKVERKP LGVEELAAAA VAASSAEPLT KARDLLCHLL LMGPTYLPNL LHLRNAQQDI
EQRARQSAAA EDSHAASVRA AKQAQRERGA AALQRSRSEA VPSPRGPSPS RKDRRNWSPG
KRDKFKAPPS PMQPHKAQSE AASAAPQQRS NEGATASSSV RDGSDGSDDW EDVYQVRRAA
NPGGSRHGRS VSMSHADSPS PAYGQEAEGD WLGPGDMGRR EANGTAGAAV FADSNFTPDP
DIPEGPQAPG TERYCFIGQP LARVVAAELC TEGSKDVVLY KIRVADASGE WTVSRRFRNF
ETLHRALRES AAYRLRLPAK RIFSQQHSVE FVEDRRQQLD AYLQALLANP VVAGCKEVWE
FLSRWSELYA LDSEGGFLRS VSAKIQGANT TMRRCCLTQL AVGDMVEEMD MTRRKSMARL
RNRGDAPDVS LDGQPMHRAS RSFSRDLGKL RHLGGGRKAN GGGQDVVTQP PPFQAMHAPG
SAGSSGTGSG SVRMLRISGP SDLINGAGQL LAAGARQVQG VKQVLQGAED RPEPRHFPTS
ALMPAPSFSV DDIPVEEFHG ELLHYSRPAS LQSQANSPTE TPLSATPASS RGHSPTRQAA
EQQRGGPAGG TQVQRRTEAT PPHTEQLHHS SSAQDLASTA KVTRFRQESM QKANSLEAPD
TSEQQADEAA LSRSAPSTGG TPQPPQPGEP PPPKPRGPPQ RGDTGHISFG GIVQSPSVAS
VAANIEAVGP PSGLRVPDLM RDDPDMADWE EAAGISAPLY DIVDTLFELQ SRGFFRRQVF
GVARQVLSLV AGGAIDEWLL SNMRALRQEH TLARLLCHLQ RQLWPGGAWF QSLPENQHPA
GKPAQRWVMT AENFLAAHGD PPIDEDEIRE AVWELLFARA PPALVRVVGK QVYHSGMADL
FEMMQSRTFM QQLGYGLLKI GLVNLFPELK LLFRKIERGA LDATAGPPGP PITTATANSG
SEPSHAAAPA ASSKPPKH
//
