ID I1C5Z0_RHIO9 Unreviewed; 493 AA.
AC I1C5Z0;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Mitochondrial group I intron splicing factor CCM1 {ECO:0000256|ARBA:ARBA00019650};
GN ORFNames=RO3G_08575 {ECO:0000313|EMBL:EIE83870.1};
OS Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL
OS 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Rhizopodaceae; Rhizopus.
OX NCBI_TaxID=246409 {ECO:0000313|EMBL:EIE83870.1, ECO:0000313|Proteomes:UP000009138};
RN [1] {ECO:0000313|EMBL:EIE83870.1, ECO:0000313|Proteomes:UP000009138}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880
RC {ECO:0000313|Proteomes:UP000009138};
RX PubMed=19578406; DOI=10.1371/journal.pgen.1000549;
RA Ma L.-J., Ibrahim A.S., Skory C., Grabherr M.G., Burger G., Butler M.,
RA Elias M., Idnurm A., Lang B.F., Sone T., Abe A., Calvo S.E.,
RA Corrochano L.M., Engels R., Fu J., Hansberg W., Kim J.-M., Kodira C.D.,
RA Koehrsen M.J., Liu B., Miranda-Saavedra D., O'Leary S.,
RA Ortiz-Castellanos L., Poulter R., Rodriguez-Romero J., Ruiz-Herrera J.,
RA Shen Y.-Q., Zeng Q., Galagan J., Birren B.W., Cuomo C.A., Wickes B.L.;
RT "Genomic analysis of the basal lineage fungus Rhizopus oryzae reveals a
RT whole-genome duplication.";
RL PLoS Genet. 5:E1000549-E1000549(2009).
CC -!- FUNCTION: RNA-binding protein involved in the specific removal of group
CC I introns in mitochondrial encoded transcripts. Maintains the stability
CC of the small subunit mitochondrial 15S rRNA and thus the expression of
CC the mitochondrial genome. {ECO:0000256|ARBA:ARBA00024866}.
CC -!- SIMILARITY: Belongs to the CCM1 family.
CC {ECO:0000256|ARBA:ARBA00006192}.
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DR EMBL; CH476737; EIE83870.1; -; Genomic_DNA.
DR AlphaFoldDB; I1C5Z0; -.
DR STRING; 246409.I1C5Z0; -.
DR VEuPathDB; FungiDB:RO3G_08575; -.
DR eggNOG; KOG4197; Eukaryota.
DR InParanoid; I1C5Z0; -.
DR OMA; IMPLEKM; -.
DR OrthoDB; 1381922at2759; -.
DR Proteomes; UP000009138; Unassembled WGS sequence.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR002885; Pentatricopeptide_rpt.
DR InterPro; IPR033443; PPR_long.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR NCBIfam; TIGR00756; PPR; 1.
DR PANTHER; PTHR47934; PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN PET309, MITOCHONDRIAL; 1.
DR PANTHER; PTHR47934:SF6; PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN PET309, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF13812; PPR_3; 3.
DR Pfam; PF17177; PPR_long; 1.
DR PROSITE; PS51375; PPR; 3.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009138}.
FT REPEAT 37..71
FT /note="PPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
FT DOMAIN 205..325
FT /note="Pentacotripeptide-repeat region of PRORP"
FT /evidence="ECO:0000259|Pfam:PF17177"
FT REPEAT 318..352
FT /note="PPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
FT REPEAT 388..422
FT /note="PPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
SQ SEQUENCE 493 AA; 56652 MW; 38B4B8D474B86A23 CRC64;
MGEKINLVRS RKSSPESVLK KVLNVVGEMN SQKLRYDLNT YNALLAAYAR AKDQTNVTET
LRKMEEEGVS PTTDSYNLIM EAFGNDKNIA LQNRLKEEMQ QKGIELNSVT YYHLLRGQQN
NIELALETLE DMKKRGIEPT LLTYSLLIRS CRAKASNTAF ALLKEAEEKG LAVQNEPRMY
FDVLRLGTRR DEYEMVNYCW NKAITEHSLR PDEGTCLQVL RVAAKKGDTK LATDVIRQLS
TNGYPYKEHY FTPLMEAFLV KDDLKSAFNV LDIMRVSGVP PTMNAIYALR EKLSKDIKTI
DKAYYILEEL RREKKAVDVT AFNVVIAACA DAGDLERTIF THREAENLGV KPDVDTYNAI
LGVCIKARVD KMDKVVIEEM KKANISPNID TYIKMIELSC NRANYEEAFS YLETMKEYGI
LPPERCYALL ARKLSHKKDP RFHLVLEEME TFGYKHKGYY MNQVRLIINQ TVKDSPCLIS
LLLTHPYLPL WMH
//
