ID   I1H7C9_BRADI            Unreviewed;       926 AA.
AC   I1H7C9;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   RecName: Full=NB-ARC domain-containing protein {ECO:0000259|Pfam:PF00931};
GN   Name=100832995 {ECO:0000313|EnsemblPlants:KQK22526};
GN   ORFNames=BRADI_1g67840v3 {ECO:0000313|EMBL:KQK22526.1};
OS   Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX   NCBI_TaxID=15368 {ECO:0000313|EMBL:KQK22526.1};
RN   [1] {ECO:0000313|EMBL:KQK22526.1, ECO:0000313|EnsemblPlants:KQK22526}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bd21 {ECO:0000313|EMBL:KQK22526.1,
RC   ECO:0000313|EnsemblPlants:KQK22526};
RX   PubMed=20148030; DOI=10.1038/nature08747;
RG   International Brachypodium Initiative;
RT   "Genome sequencing and analysis of the model grass Brachypodium
RT   distachyon.";
RL   Nature 463:763-768(2010).
RN   [2] {ECO:0000313|EMBL:KQK22526.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Bd21 {ECO:0000313|EMBL:KQK22526.1};
RG   The International Brachypodium Initiative;
RA   Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA   Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA   Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT   "WGS assembly of Brachypodium distachyon.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EnsemblPlants:KQK22526}
RP   IDENTIFICATION.
RC   STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQK22526};
RG   EnsemblPlants;
RL   Submitted (AUG-2018) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC       {ECO:0000256|ARBA:ARBA00008894}.
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DR   EMBL; CM000880; KQK22526.1; -; Genomic_DNA.
DR   RefSeq; XP_003558328.1; XM_003558280.3.
DR   AlphaFoldDB; I1H7C9; -.
DR   STRING; 15368.I1H7C9; -.
DR   EnsemblPlants; KQK22526; KQK22526; BRADI_1g67840v3.
DR   GeneID; 100832995; -.
DR   Gramene; KQK22526; KQK22526; BRADI_1g67840v3.
DR   KEGG; bdi:100832995; -.
DR   eggNOG; KOG4658; Eukaryota.
DR   HOGENOM; CLU_000427_4_0_1; -.
DR   InParanoid; I1H7C9; -.
DR   OMA; ASGQCKV; -.
DR   OrthoDB; 10336at2759; -.
DR   Proteomes; UP000008810; Chromosome 1.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0098542; P:defense response to other organism; IBA:GO_Central.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR33463:SF190; NB-ARC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR33463; NB-ARC DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   Pfam; PF00560; LRR_1; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51450; LRR; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008810}.
FT   DOMAIN          175..405
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
SQ   SEQUENCE   926 AA;  101327 MW;  FCAD219C2A7E3FF2 CRC64;
     MEMQFAAVLA SLALGGALLV LFFGKWWQPL ADADRRVKEL DDAVEALLQL RAAVLKQLDG
     APESEQTRAW LRRAQEAQDE VASIKARHDA GQLYVIRLLQ YFLAAGAVAA GALAEKQLKI
     VRAIQEQGAA LLEAALATPQ APPPLLLQPE ELELPLPATT GATRARLNEA LRFLGDCDAA
     LGVWGAGGVG KTTLLKHVRG VCGRVAPFFD HVFLVAASRD CTVANLQREV VAVLGLREAP
     TEQAQAAGIL SFLRDKSFLL LLDGVWERLD LERVGIPQPF GVVAGRVRKV IVASRSETVC
     ADMGCRKKIK MERLNEDDAW NLFEGNVGEE AVRWDTQIST LARQVAAECK GLPLCLAIVG
     RAMSNKRTPE EWSNALDKLK NPQLSSGKSG PDESTHALVK FCYDNLESDM ARECMLTCAL
     WPEDHNISKD ELLQCWIGLG LLPINLAAGN DDVEEAHRLG HSVLSILESA RLLEQGDNHR
     YNMCPSDTHV RLHDALRDAA LRFAPGKWLV RAGVGLREPP RDEALWRDAQ RVSLMHNAIE
     EAPAKAAAAG LSDAQPASLM LQCNRALPRK MLQAIQHFTR LTYLDLEDTG IVDAFPMEIC
     CLVSLEYLNL SRNRILSLPM ELGNLSGLKY LHMRDNYYIQ ITIPAGLISR LGKLQVLELF
     TASIVSVADD YVAPVIDDLE SSGASVASLG IWLDNTRDVQ RLASLAPAGV RVRSLHLRKL
     AGARSLELLS AQHAAELGGV QEHLRELVVY SSDVVEIVAD AHAPRLEVVK FGFLTRLHTM
     EWSHGAASCL REVAMGACHT LTHITWVQHL PCLESLNLSG CNGMTRLLGG AAEGGSAAEE
     LVTFPRLRLL ALLGLAKLEA VRDGGGECAF PELRRLQTRG CSRLRRIPMR PASGQGKVRV
     EADRHWWNGL QWAGDDVKSC FVPVLL
//