ID I1HPV1_BRADI Unreviewed; 590 AA.
AC I1HPV1;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Auxin efflux carrier component {ECO:0000256|RuleBase:RU362108};
GN Name=100826548 {ECO:0000313|EnsemblPlants:KQK08941};
GN ORFNames=BRADI_2g44987v3 {ECO:0000313|EMBL:KQK08941.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQK08941.1};
RN [1] {ECO:0000313|EMBL:KQK08941.1, ECO:0000313|EnsemblPlants:KQK08941}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK08941.1,
RC ECO:0000313|EnsemblPlants:KQK08941};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQK08941.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK08941.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK08941}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQK08941};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- FUNCTION: May act as a component of the auxin efflux carrier.
CC {ECO:0000256|RuleBase:RU362108}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362108}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362108}.
CC -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69.1) family.
CC {ECO:0000256|ARBA:ARBA00009177, ECO:0000256|RuleBase:RU362108}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362108}.
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DR EMBL; CM000881; KQK08941.1; -; Genomic_DNA.
DR RefSeq; XP_010232076.1; XM_010233774.2.
DR AlphaFoldDB; I1HPV1; -.
DR STRING; 15368.I1HPV1; -.
DR EnsemblPlants; KQK08941; KQK08941; BRADI_2g44987v3.
DR GeneID; 100826548; -.
DR Gramene; KQK08941; KQK08941; BRADI_2g44987v3.
DR KEGG; bdi:100826548; -.
DR eggNOG; ENOG502QRM7; Eukaryota.
DR HOGENOM; CLU_019285_1_1_1; -.
DR InParanoid; I1HPV1; -.
DR OMA; GAGQHQM; -.
DR OrthoDB; 405852at2759; -.
DR Proteomes; UP000008810; Chromosome 2.
DR GO; GO:0009921; C:auxin efflux carrier complex; IEA:EnsemblPlants.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0010329; F:auxin efflux transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0010315; P:auxin export across the plasma membrane; IBA:GO_Central.
DR GO; GO:0009926; P:auxin polar transport; IBA:GO_Central.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-UniRule.
DR InterPro; IPR014024; Auxin_eff_plant.
DR InterPro; IPR004776; Mem_transp_PIN-like.
DR NCBIfam; TIGR00946; 2a69; 1.
DR PANTHER; PTHR31752; AUXIN EFFLUX CARRIER COMPONENT 1B-RELATED; 1.
DR PANTHER; PTHR31752:SF18; AUXIN EFFLUX CARRIER COMPONENT 4; 1.
DR Pfam; PF03547; Mem_trans; 1.
PE 3: Inferred from homology;
KW Auxin signaling pathway {ECO:0000256|ARBA:ARBA00023294,
KW ECO:0000256|RuleBase:RU362108};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362108};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362108};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362108}; Transport {ECO:0000256|RuleBase:RU362108}.
FT TRANSMEM 6..30
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 42..60
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 80..98
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 105..126
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 132..152
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 445..462
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 474..493
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 505..529
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT TRANSMEM 562..584
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362108"
FT REGION 234..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 358..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..295
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..384
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 62913 MW; DBF785974800EFDB CRC64;
MISSHDLYTV LAAVVPLYVA MILAYGSVRW WGIFTPDQCS GINRFVAIFA VPLLSFHFIS
ASDPYQMNLR FLAADTLQKL LVLAALAACS RLIPSLGLDW SVTLFSLSTL PNTLVMGIPL
LVAMYGPDAG SLMVQIVVLQ CIIWYTLLLF LFEFRAARAL IADQFPDTAA SIASLHVDPD
VVSLDGGRAE TEAEVAPDGR LRVTVRRSSV SRQSLSLLGV TPRPSNLTGA EIYSVNSSQN
PTPRGSNFNH ADFFATVGAP PPPTTPAGAR GSSFGTSSEH FSLHTSSQGP TPRGSNFDEH
SAGAGGRKPA AAGAHSSHDA KELHMFVWSS STSPVSEVSR LPADRARLDA KEIRMVVPAD
PPQNGSCKEA AVEDDGEAAE AGRERLTKLS SSSTAELRPN VYADTAGAED AKRPRQQHQM
PPASVMTRLI LIMVWRKLIR NPNTYSSLIG LVWSLAAFRW HISMPSIVGK SISILSDAGL
GMAMFSLGLF MALQPSIIAC GNTVAVVSMV VRFIVGPAVI AAASAAVGLR GTLFKISIVQ
AALPQGIVPF VFAKEYNVHP TILSTAVIFG MLVALPITLA YYAILGLVTV
//
