ID I1HU38_BRADI Unreviewed; 294 AA.
AC I1HU38;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase {ECO:0000256|ARBA:ARBA00012526};
DE EC=2.7.7.60 {ECO:0000256|ARBA:ARBA00012526};
GN Name=100829889 {ECO:0000313|EnsemblPlants:KQK10954};
GN ORFNames=BRADI_2g57260v3 {ECO:0000313|EMBL:KQK10954.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EnsemblPlants:KQK10954};
RN [1] {ECO:0000313|EMBL:KQK10954.1, ECO:0000313|EnsemblPlants:KQK10954}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK10954.1,
RC ECO:0000313|EnsemblPlants:KQK10954};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQK10954.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK10954.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK10954}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQK10954};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- PATHWAY: Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis
CC via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-
CC phosphate: step 2/6. {ECO:0000256|ARBA:ARBA00004787}.
CC -!- SIMILARITY: Belongs to the IspD/TarI cytidylyltransferase family. IspD
CC subfamily. {ECO:0000256|ARBA:ARBA00009789}.
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DR EMBL; CM000881; KQK10954.1; -; Genomic_DNA.
DR RefSeq; XP_003564801.1; XM_003564753.3.
DR AlphaFoldDB; I1HU38; -.
DR STRING; 15368.I1HU38; -.
DR EnsemblPlants; KQK10954; KQK10954; BRADI_2g57260v3.
DR GeneID; 100829889; -.
DR Gramene; KQK10954; KQK10954; BRADI_2g57260v3.
DR KEGG; bdi:100829889; -.
DR eggNOG; ENOG502QUUE; Eukaryota.
DR HOGENOM; CLU_061281_0_1_1; -.
DR InParanoid; I1HU38; -.
DR OMA; TPMLIHA; -.
DR OrthoDB; 1214813at2759; -.
DR UniPathway; UPA00056; UER00093.
DR Proteomes; UP000008810; Chromosome 2.
DR GO; GO:0050518; F:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity; IBA:GO_Central.
DR GO; GO:0019288; P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway; IEA:UniProtKB-UniPathway.
DR CDD; cd02516; CDP-ME_synthetase; 1.
DR HAMAP; MF_00108; IspD; 1.
DR InterPro; IPR001228; IspD.
DR InterPro; IPR034683; IspD/TarI.
DR InterPro; IPR018294; ISPD_synthase_CS.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR NCBIfam; TIGR00453; ispD; 1.
DR PANTHER; PTHR32125; 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC; 1.
DR PANTHER; PTHR32125:SF4; 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC; 1.
DR Pfam; PF01128; IspD; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR PROSITE; PS01295; ISPD; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 294 AA; 32528 MW; 2618B501AA74A99D CRC64;
MELRLCLRLH ARLPSAPKRS RLPSPAMVLL PASGRLRIGW SCGDAPRRIP NSAIFAVRAD
GAQGDAVKER SVSVILLSGG QGKRMGANMP KQYIPLLGTP IALHSLRTFC RMKEVKEVIV
VCDPSYRNVF EDSIENLQIP IKFACPGKER QDSVFNGLQE IDRDSELVCV HDSARPLVSS
KDVKKVLEDA AVHGAAVLGV PVKATIKEAS SDSFVVKTLD RKTLWEMQTP QVMEPNLLKD
GFDLVKRDGL EVTDDVSIVE YLKHPVYITE GSYTNIKVTT PDDLLLAERL MNEE
//
