ID I1IQB0_BRADI Unreviewed; 978 AA.
AC I1IQB0;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN Name=100836491 {ECO:0000313|EnsemblPlants:KQJ90322};
GN ORFNames=BRADI_4g30850v3 {ECO:0000313|EMBL:KQJ90322.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQJ90322.1};
RN [1] {ECO:0000313|EMBL:KQJ90322.1, ECO:0000313|EnsemblPlants:KQJ90322}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ90322.1,
RC ECO:0000313|EnsemblPlants:KQJ90322};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQJ90322.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ90322.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQJ90322}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQJ90322};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR EMBL; CM000883; KQJ90322.1; -; Genomic_DNA.
DR RefSeq; XP_003576552.1; XM_003576504.3.
DR AlphaFoldDB; I1IQB0; -.
DR STRING; 15368.I1IQB0; -.
DR EnsemblPlants; KQJ90322; KQJ90322; BRADI_4g30850v3.
DR GeneID; 100836491; -.
DR Gramene; KQJ90322; KQJ90322; BRADI_4g30850v3.
DR KEGG; bdi:100836491; -.
DR eggNOG; KOG1052; Eukaryota.
DR HOGENOM; CLU_007358_0_2_1; -.
DR InParanoid; I1IQB0; -.
DR OMA; WTFMELA; -.
DR OrthoDB; 1011589at2759; -.
DR Proteomes; UP000008810; Chromosome 4.
DR ExpressionAtlas; I1IQB0; baseline and differential.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR18966:SF566; GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037090-50};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT TRANSMEM 595..613
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 655..671
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 833..855
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 472..811
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT REGION 931..978
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 759..814
FT /evidence="ECO:0000256|PIRSR:PIRSR037090-50"
SQ SEQUENCE 978 AA; 109120 MW; FF92691BDBC19982 CRC64;
MGAVSTLLQA EMRAVLSALL RVLRRHDFLR LVLVLLVFGS SGVTAQGGAR RQRQVVDVGV
ILDMKTWLGN TSWACMEMAL EDFYANATQA RYRTRLKLHL RDTGPDAVDA ASAGVDLLKN
VHVQAIVGPQ TSTQAKFLAE LGNKSSVPII SFSADCPSRS GQTPYFIRTA WNDSSQAEAI
ASLVKKYNWR EVVPVFEDDD SNTRFIPDLV DALRQVDARV SYRCKIHPSA KEDDIRRAIS
GLKYNWTSVF VVRMSHLLAF KFFQLAKDEG MMGQDFVWIT AYGLTDIFDV VGSPALDVMQ
GVLGVKPHVQ DTVELQNFTR RWRKKHRLEN PGTSLSEPTV SGLYAYDTIW ALALAAEETR
YNDSNFVSVT NNGSTDFERI GTSKAAEKLR GTLLKTNFQG MSGKFQIQDM QLLSSKYEII
NIVGQEKRVA GFWTPEFSIS GNSSSMAELG TIIWPGGNKT PPRGWMLPMN KTLKIGVPVK
PGFAEFVKFE NGIAKGFCID VFEAVVRELP YNVSCNYSEF GDGKVSKGTY DDLVYRVYLK
EYDAVVGDIT ILANRSKYVD FTLPYTESGV RMLVPVRDQR QKTAWTFLKP LTTDLWLGTG
AFFIFTGFVV WFIEHRTNKD FRGPPASQIG SVFYFSFSTL VFAHKERIVN NLSRIVLVVW
LFVVLIVQQS YTASLSSILT VEQLQPTVTN LEEVIRKGSY VGYLNDSFLP GLLKRLKIDE
SKMIAFDSPA EYNEALSTGK VAVIVDEIPY LKVFLSRYCQ NYTMIGPTYK FDGFGYAFPR
GSPLTPDISR GILKFASDSK MVELQKTLYG DMSCPDKDDS QISSSLTLHS FQGLFIITGA
SSMLALILHA VITVYNNQHD LSSDNSLTSW RRWLAIISKL FHEGDSPNTP DKDELAMANV
DSIIESPLSI PNHVIERLDS GTDTGSLPEV EGTADRDLSV QDAEPTPSAY VHSERGHNGV
ASLSRSGSSI RRRQRIME
//
