ID I1IU93_BRADI Unreviewed; 492 AA.
AC I1IU93;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
GN Name=100842082 {ECO:0000313|EnsemblPlants:KQJ92205};
GN ORFNames=BRADI_4g42230v3 {ECO:0000313|EMBL:KQJ92205.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EnsemblPlants:KQJ92205};
RN [1] {ECO:0000313|EMBL:KQJ92205.1, ECO:0000313|EnsemblPlants:KQJ92205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ92205.1,
RC ECO:0000313|EnsemblPlants:KQJ92205};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQJ92205.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ92205.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQJ92205}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQJ92205};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
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DR EMBL; CM000883; KQJ92205.1; -; Genomic_DNA.
DR RefSeq; XP_003578894.1; XM_003578846.2.
DR AlphaFoldDB; I1IU93; -.
DR STRING; 15368.I1IU93; -.
DR EnsemblPlants; KQJ92205; KQJ92205; BRADI_4g42230v3.
DR GeneID; 100842082; -.
DR Gramene; KQJ92205; KQJ92205; BRADI_4g42230v3.
DR KEGG; bdi:100842082; -.
DR eggNOG; KOG4270; Eukaryota.
DR HOGENOM; CLU_031591_1_0_1; -.
DR InParanoid; I1IU93; -.
DR OMA; IDIHCLS; -.
DR OrthoDB; 5480623at2759; -.
DR Proteomes; UP000008810; Chromosome 4.
DR ExpressionAtlas; I1IU93; baseline.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00132; CRIB; 1.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR000095; CRIB_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR044785; RopGAP1-5.
DR PANTHER; PTHR23177; MKIAA1688 PROTEIN; 1.
DR PANTHER; PTHR23177:SF64; RHO GTPASE-ACTIVATING PROTEIN 1; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00285; PBD; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008810}.
FT DOMAIN 150..330
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 35..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 330..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 437..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..371
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 395..417
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 492 AA; 53777 MW; 41377DC35FA5AF07 CRC64;
MTEVAILRGP TNLASPASRA SSSLRYLANA DSDVLHRGSR AENPTGSTGG LRLEGRRERE
VEGSEEEEER WSFLELLLEL LRKSLFGCRE EGGGGGESGG CGMEIGWPTE VQHVAHVTFD
RFHGFLGLPV EFEPEVPRRA PSASASVFGV STESMQCSYD SRRNSVPTIL LMMQRRLYEQ
GGLRAEGIFR INAENSQEEL VRDQLNSGII PYGIDVHCLA GLIKAWFREL PSGVLDPIPP
EQVMQCQSEE DCVRVAKCLP PAEAGLLDWA VNLMADVVQE EQINKMNARN IAMVFAPNMT
QMVDPLTALM YAVQVMNFLK MLIQKTLKDR EESNLEDGSL PQKDPSDENG HHNPSLPVDS
HHEEESRRPS FVSEEPLLNS PAHITKDKPN ETTPAGGHSA PSGQTGNVLT NMEGFSSWSE
PLPAPLATAN ASCATTVNSL QGKGSRSLNS RRTRKGKGQS GTPAVAPAEK KSRGASIVSR
LNSTVERIEA WR
//
