ID I1J3D3_BRADI Unreviewed; 688 AA.
AC I1J3D3;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Tr-type G domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=100840685 {ECO:0000313|EnsemblPlants:KQJ85300};
GN ORFNames=BRADI_5g26197v3 {ECO:0000313|EMBL:KQJ85300.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQJ85300.1};
RN [1] {ECO:0000313|EMBL:KQJ85300.1, ECO:0000313|EnsemblPlants:KQJ85300}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ85300.1,
RC ECO:0000313|EnsemblPlants:KQJ85300};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQJ85300.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQJ85300.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQJ85300}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQJ85300};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- FUNCTION: This protein promotes the GTP-dependent binding of aminoacyl-
CC tRNA to the A-site of ribosomes during protein biosynthesis.
CC {ECO:0000256|ARBA:ARBA00003982}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM000884; KQJ85300.1; -; Genomic_DNA.
DR RefSeq; XP_010240611.1; XM_010242309.2.
DR AlphaFoldDB; I1J3D3; -.
DR STRING; 15368.I1J3D3; -.
DR EnsemblPlants; KQJ85300; KQJ85300; BRADI_5g26197v3.
DR GeneID; 100840685; -.
DR Gramene; KQJ85300; KQJ85300; BRADI_5g26197v3.
DR KEGG; bdi:100840685; -.
DR eggNOG; KOG0458; Eukaryota.
DR HOGENOM; CLU_007265_3_3_1; -.
DR InParanoid; I1J3D3; -.
DR OMA; CGYKDSA; -.
DR OrthoDB; 470716at2759; -.
DR Proteomes; UP000008810; Chromosome 5.
DR ExpressionAtlas; I1J3D3; baseline.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006412; P:translation; IBA:GO_Central.
DR CDD; cd01883; EF1_alpha; 1.
DR CDD; cd04093; HBS1_C_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR InterPro; IPR001876; Znf_RanBP2.
DR PANTHER; PTHR23115:SF244; OS04G0677800 PROTEIN; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00547; ZnF_RBZ; 1.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
DR PROSITE; PS01358; ZF_RANBP2_1; 1.
DR PROSITE; PS50199; ZF_RANBP2_2; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00322};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00322}.
FT DOMAIN 18..47
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 255..487
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 177..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..197
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 688 AA; 74779 MW; 83B39926E1BDF69B CRC64;
MFVPKTDNQS DLEEPCRNPG PWQCTICTHQ NETSYISCEL CGVLRNLSLY FNNAVGTEGG
AKRRNKHSGV SVLARSLFSP PSPKSKAVVF SDGFQGNTNT TGYMQASLDA LHETYMTHKQ
RRVNIVPFKF DTPSPDDMVS AGLKSFKHVR KVNAEAPSID SVDIAGKKVM DDHDLVTQDA
HTDPSSSAKL DELGGNGSSV DVHIQNKTPV LDDELQHLSL EGKPKNIKAK IKKPVSVSQY
KAEPWMLQGE DQKMPRQLNL AIVGHVDSGK STLCGRLLHA LGRISKKQMH KNEKEAKEKG
KGSFAYAWAM DESAEERARG VTMTVGVAYF DTENYQVVLL DSPGHKDFVP NMISGATQSD
AAVLVVDASV GSFESGMGVN GIGQTKEHAQ LIRSFGVENL IVAVNKMDSV EYSKERFSFV
KSQLGMYLRS CGYKESAISW VPLSAMNNEN LVTVASDTRL SSWYDGNCLL KAIDSLAPPR
RDVSKPLRLP ICDVVSSHML GQVAVCGKVA TGAIRSDSKV LVMPSGELAT VRIIERDSSR
LNLARAGDNI AIGLQGIDPI HVTSGGVLCH PDYPVSVASS LELKILVLDI TVPILVGLQF
ELHIHHAKVS ASLVKILSLL DQKTGKASAK KPRMLTARQA AIIEVKLERE VCVEEFSALK
ALGRAFLRSQ GITVAVGVVT RVPEQVQV
//
