ID I1MIM1_SOYBN Unreviewed; 1005 AA.
AC I1MIM1;
DT 13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 1.
DT 24-JAN-2024, entry version 70.
DE RecName: Full=Retinoblastoma-related protein {ECO:0008006|Google:ProtNLM};
GN Name=100779266 {ECO:0000313|EnsemblPlants:KRH13310};
GN ORFNames=GLYMA_15G230300 {ECO:0000313|EMBL:KRH13310.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EMBL:KRH13310.1};
RN [1] {ECO:0000313|EMBL:KRH13310.1, ECO:0000313|EnsemblPlants:KRH13310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRH13310};
RC TISSUE=Callus {ECO:0000313|EMBL:KRH13310.1};
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [2] {ECO:0000313|EnsemblPlants:KRH13310}
RP IDENTIFICATION.
RC STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRH13310};
RG EnsemblPlants;
RL Submitted (FEB-2018) to UniProtKB.
RN [3] {ECO:0000313|EMBL:KRH13310.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Callus {ECO:0000313|EMBL:KRH13310.1};
RA Schmutz J., Cannon S., Schlueter J., Ma J., Mitros T., Nelson W., Hyten D.,
RA Song Q., Thelen J., Cheng J., Xu D., Hellsten U., May G., Yu Y.,
RA Sakurai T., Umezawa T., Bhattacharyya M., Sandhu D., Valliyodan B.,
RA Lindquist E., Peto M., Grant D., Shu S., Goodstein D., Barry K.,
RA Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N., Joshi T.,
RA Libault M., Sethuraman A., Zhang X., Shinozaki K., Nguyen H., Wing R.,
RA Cregan P., Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.,
RA Jackson S.;
RT "WGS assembly of Glycine max.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the retinoblastoma protein (RB) family.
CC {ECO:0000256|ARBA:ARBA00009475}.
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DR EMBL; CM000848; KRH13310.1; -; Genomic_DNA.
DR RefSeq; XP_006598087.1; XM_006598024.2.
DR AlphaFoldDB; I1MIM1; -.
DR SMR; I1MIM1; -.
DR STRING; 3847.I1MIM1; -.
DR PaxDb; 3847-GLYMA15G36890-1; -.
DR EnsemblPlants; KRH13310; KRH13310; GLYMA_15G230300.
DR GeneID; 100779266; -.
DR Gramene; KRH13310; KRH13310; GLYMA_15G230300.
DR KEGG; gmx:100779266; -.
DR eggNOG; KOG1010; Eukaryota.
DR HOGENOM; CLU_015949_0_0_1; -.
DR InParanoid; I1MIM1; -.
DR OrthoDB; 519973at2759; -.
DR Proteomes; UP000008827; Chromosome 15.
DR ExpressionAtlas; I1MIM1; baseline and differential.
DR GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005667; C:transcription regulator complex; IBA:GO_Central.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.472.140; -; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR002720; RB_A.
DR InterPro; IPR002719; RB_B.
DR InterPro; IPR028309; RB_fam.
DR InterPro; IPR024599; RB_N.
DR PANTHER; PTHR13742:SF17; RETINOBLASTOMA-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR13742; RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED; 1.
DR Pfam; PF11934; DUF3452; 1.
DR Pfam; PF01858; RB_A; 1.
DR Pfam; PF01857; RB_B; 1.
DR SMART; SM01367; DUF3452; 1.
DR SMART; SM01368; RB_A; 1.
DR SUPFAM; SSF47954; Cyclin-like; 2.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008827};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 74..222
FT /note="Retinoblastoma-associated protein N-terminal"
FT /evidence="ECO:0000259|SMART:SM01367"
FT DOMAIN 404..605
FT /note="Retinoblastoma-associated protein A-box"
FT /evidence="ECO:0000259|SMART:SM01368"
FT REGION 376..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1005 AA; 112113 MW; BFD1325E6522BCFE CRC64;
MEDGKPMNGG DQVESRFVEF CKNGLALEEK SCKKAKNLFG ETKHILLSNF SSMGNGTSEE
AERYWFAFIL YSVKKLIQKN EEGGKEDAEN TGLSLCRILR AAKLNIADFF KELPQFVVKA
GPTLSNLYGT DWENRLEAKE MHANAIHLKI LSKYYKRVFG EFFVSTDTNA EKNSSITVHA
SEYHRFGWLL FLALRVHAFS RFKDLVTCTN GLISILAILI IHVPTRFRNF NIHDSSRFVK
KSNKGVDLLA SLCNIYNTSE DELRKTMEKA NNVIADILKK QPCLASECET ENLENIDKDG
LTYFKDLMEE SSLPSSLNML EKDYDYMIRN KSELDERLFI NEDDSLLASV SLSGGSVSVG
GVKRKFDSMA SPAKTITSPL SPHRSPTSHT NGIPGSANSK MAATPVSTAM TTAKWLRTVI
SPLPSKPSPE LERFLTSCDR DVTSDVVRRA QIILQAIFPS SPLGERCVTG SLQSANLMDN
IWAEQRRLEA LKLYYRVLEA MCRAEAQVFH ATNLTSLLTN ERFHRCMLAC SAELVLATHK
TVTMLFPAVL ERTGITAFDL SKVIESFIRH EESLPRELRR HLNSLEERLL ESMVWEKGSS
MYNSLAVARP SLSAEINRLG LLAEPMPSLD EIAMHINFSC GGLPPVPTLP KLESSPTQNG
DIRSPKRNVL MERNSFTSPV KDRLLPFNSL KSKLPPPPLQ SAFASPTKPN PGGGGETCAE
TGINIFFGKI IKLGAVRISG MVERLQLSQQ IRENVYCLFQ RILNQWTSLF FNHHIDQIIL
CCFYGVAKIS QLNLTFKEIV YNYRKQPHCK TQVFRSVFVD WSLARRNGRT GQDHVDIITF
YNEIFIPSVK PLLVELGPAG PTPKSDRIPE VNNKNEGHLA QCPGSPKISP FPTLPDMSPK
KVSATHNVYV SPLRSSKMEA LISHSSKSYY ACVGESTHAY QSPSKDLTAI NNRLNGNRKV
RGPLNFDDVD VGLVSDSMVA NSLYLQNGSC ASSSGAPLKS EQPDS
//
