ID   I1R6H2_ORYGL            Unreviewed;      1013 AA.
AC   I1R6H2;
DT   13-JUN-2012, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2012, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Oryza glaberrima (African rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX   NCBI_TaxID=4538 {ECO:0000313|EnsemblPlants:ORGLA12G0112800.1, ECO:0000313|Proteomes:UP000007306};
RN   [1] {ECO:0000313|Proteomes:UP000007306}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IRGC 96717 {ECO:0000313|Proteomes:UP000007306};
RA   Wing R.A., Yu Y., Rounsley S., Reddy-Marri P., Goicoechea J.L.,
RA   Sisneros N., Lee S., Song X., Angelova A., Kudrna D.P., de Baynast K.,
RA   Zuccolo A.;
RT   "The complete genome of Oryza glaberrima.";
RL   Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblPlants:ORGLA12G0112800.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC       {ECO:0000256|ARBA:ARBA00008894}.
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DR   AlphaFoldDB; I1R6H2; -.
DR   STRING; 4538.I1R6H2; -.
DR   EnsemblPlants; ORGLA12G0112800.1; ORGLA12G0112800.1; ORGLA12G0112800.
DR   Gramene; ORGLA12G0112800.1; ORGLA12G0112800.1; ORGLA12G0112800.
DR   eggNOG; KOG4658; Eukaryota.
DR   HOGENOM; CLU_000837_8_3_1; -.
DR   OMA; RDCPRIS; -.
DR   Proteomes; UP000007306; Unassembled WGS sequence.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR041118; Rx_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   PANTHER; PTHR23155:SF1233; OS09G0365000 PROTEIN; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF18052; Rx_N; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821}.
FT   DOMAIN          62..129
FT                   /note="Disease resistance N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18052"
FT   DOMAIN          226..453
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
SQ   SEQUENCE   1013 AA;  116067 MW;  D8ABD38A57D52D22 CRC64;
     MQTRFTNMSW GAAARGLQTA TGLVTSVNTW AEFFNCVSSA ISSACSWINI HQKPENDFVQ
     EEMKHLQSDL WQLQTTLPKM RNLVEILEWQ IYKKPAAELL PHIKDAVLDA EDIIDEFNYY
     ELKAKIEGRI EECLTSSGCQ EFYTSVIRGS FNRVKEIQEK LDHLHRQSMD LGLHCAAQRF
     DKIVRPETSS FLNESKIFGR QEEEKMVLEL LGVQLQANAG YKRKRSSRVE VLPIVGLGGV
     GKTTLAQQIC KNQMVKAHFD MILWACVSDD FNTKRLTKEV IQSSKKETSF DNLDSLQSIL
     KDIVESKRFL LVLDDIWDDV MADGGQDWQR FCAPLSNAFH GSMILITTRS QKVADKVRTM
     DCFPLEGLTE DVFWEFFIVQ AFGTESLSKY PDLEDIGRSI ILKLKGSPLA AKTIGRLLRT
     NLHASHWNNI LQSELWKLEQ ERTDILPALR LSYMHLPPHL KRCFSFCAVY PKDYRFEKDT
     LVDIWLAEGF VEHVSSIPAV TVLHQYFEEL LSRSFFQKVT CNKYVIHDLM HDMAQLVSQD
     ECFIIRNADD LRTIPPNVRH LSIFTKRYIG CRDLMGLCRY KKLRTLLCSK AFSKGEFASV
     LGSWFKELQH IRVLSCSLPM IEDIPEGISN LKLVGYICFS SQRTFSILPS SFCCLYNLQT
     LDASTCVFRS LPCDFGNLIS LRKFRAKNFS YLPGEDSRMQ FLRGERIKVL KYVNQVQGSL
     LVNLPGLKSK KNIGLVVLKK ENDLYSLHMS QLAENAIYEQ EQLEVYESLH PHPDLQHLEV
     TGYQGENFCP SWFLPDNLPN MISFIFEECH NAKKISLHRL PCTGFRYLIN LYIIECTNLS
     SIKQFLQPCH IPAIKMISIK GCQELSSISA ERFGGFRFLE ALVIRDCPRI SWENGLALPP
     TLTSLSLVRC GDISKWIPDC LLNLSSLVRL QLVGLSGTMF IPGSIWRNNL PLLDYLEICN
     FQELRFTGVP EAIAEINNVL IDKCPILKEL KQPFSRGDVT FLWGIPTSKW YLS
//