ID I1ZJL9_STRPA Unreviewed; 385 AA.
AC I1ZJL9;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Methyltransferase {ECO:0000313|EMBL:AFJ25243.1};
GN ORFNames=Spaf_0218 {ECO:0000313|EMBL:AFJ25243.1};
OS Streptococcus parasanguinis FW213.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1114965 {ECO:0000313|EMBL:AFJ25243.1, ECO:0000313|Proteomes:UP000002865};
RN [1] {ECO:0000313|EMBL:AFJ25243.1, ECO:0000313|Proteomes:UP000002865}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FW213 {ECO:0000313|EMBL:AFJ25243.1,
RC ECO:0000313|Proteomes:UP000002865};
RX PubMed=22529932; DOI=10.1371/journal.pone.0034769;
RA Geng J., Chiu C.H., Tang P., Chen Y., Shieh H.R., Hu S., Chen Y.Y.;
RT "Complete Genome and Transcriptomes of Streptococcus parasanguinis FW213:
RT Phylogenic Relations and Potential Virulence Mechanisms.";
RL PLoS ONE 7:E34769-E34769(2012).
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DR EMBL; CP003122; AFJ25243.1; -; Genomic_DNA.
DR RefSeq; WP_003018161.1; NC_017905.1.
DR AlphaFoldDB; I1ZJL9; -.
DR STRING; 1114965.Spaf_0218; -.
DR PaxDb; 1114965-Spaf_0218; -.
DR KEGG; scf:Spaf_0218; -.
DR PATRIC; fig|1114965.3.peg.212; -.
DR eggNOG; COG0116; Bacteria.
DR HOGENOM; CLU_032119_3_1_9; -.
DR Proteomes; UP000002865; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:AFJ25243.1};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000313|EMBL:AFJ25243.1}.
FT DOMAIN 45..159
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 385 AA; 43386 MW; B4CD4CA56F3B509B CRC64;
MKKHFELIAT AAAGLEAVVG RELRNLGYDC QVENGRVRFQ GDSRTIIETN LWLRAADRVK
IVVGSFPAKT FEELFQGVFA LDWENYLPLG ARFPISKAKC VKSKLHNEPS VQAISKKAVV
KKLQRHYARP EGVPLIENGA EFKIEVSILK DQATVLIDTT GSSLFKRGYR TEKGGAPIKE
NMAAAILQLS NWYPDKPLID PTCGSGTFCI EAAMIARNMA PGLRRTFSFE EWNWVDDRLI
QEVRTEASKK INRDLVLDIM GTDIDARMID IAKENARKAG VSSDITFKQM RVQDLRSDKI
NGVIISNPPY GERLSDDVGV TKLYAEMGQV FAPLKTWSKF ILTSDESFES KYGSKADKKR
KLYNGTLKVD LYQYFGERVK RQIKA
//
