ID I2ACG5_9MYCO Unreviewed; 2150 AA.
AC I2ACG5;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Putative DNA helicase {ECO:0000313|EMBL:AFJ34989.1};
GN ORFNames=W7S_10080 {ECO:0000313|EMBL:AFJ34989.1};
OS Mycobacterium sp. MOTT36Y.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1168287 {ECO:0000313|EMBL:AFJ34989.1, ECO:0000313|Proteomes:UP000002868};
RN [1] {ECO:0000313|EMBL:AFJ34989.1, ECO:0000313|Proteomes:UP000002868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MOTT36Y {ECO:0000313|EMBL:AFJ34989.1,
RC ECO:0000313|Proteomes:UP000002868};
RX PubMed=22815454; DOI=10.1128/JB.00752-12;
RA Kim B.J., Choi B.S., Choi I.Y., Lee J.H., Chun J., Hong S.H., Kook Y.H.,
RA Kim B.J.;
RT "Complete genome sequence of Mycobacterium intracellulare clinical strain
RT MOTT-36Y, belonging to the INT5 genotype.";
RL J. Bacteriol. 194:4141-4142(2012).
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DR EMBL; CP003491; AFJ34989.1; -; Genomic_DNA.
DR RefSeq; WP_014711447.1; NC_017904.1.
DR KEGG; mmm:W7S_10080; -.
DR PATRIC; fig|1168287.3.peg.2058; -.
DR HOGENOM; CLU_000788_0_0_11; -.
DR Proteomes; UP000002868; Chromosome.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.10.620.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR025103; DUF4011.
DR InterPro; IPR041650; HEPN_Swt1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049468; Restrct_endonuc-II-like_dom.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF525; HELICASE SENATAXIN-RELATED; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF13195; DUF4011; 1.
DR Pfam; PF18731; HEPN_Swt1; 1.
DR Pfam; PF18741; MTES_1575; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:AFJ34989.1};
KW Helicase {ECO:0000313|EMBL:AFJ34989.1};
KW Hydrolase {ECO:0000313|EMBL:AFJ34989.1};
KW Nucleotide-binding {ECO:0000313|EMBL:AFJ34989.1}.
FT DOMAIN 13..126
FT /note="Swt1-like HEPN"
FT /evidence="ECO:0000259|Pfam:PF18731"
FT DOMAIN 859..995
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 1556..1755
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT DOMAIN 1806..1901
FT /note="Restriction endonuclease type II-like"
FT /evidence="ECO:0000259|Pfam:PF18741"
FT REGION 147..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1916..1950
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2150 AA; 234922 MW; 8B0BADA1CAF5A352 CRC64;
MSEKNYHIVV GEALSILIDG LSPFVEEVCA KSLPPSVSWT EVLRRKDAAA GRQMGMYKAR
DLSLMLRAMT ERLGEYGFPF NRQLSRLGQS YASELRDVRN RWAHNETFSA AEAYRAIDSI
ELLLRAANAP GGATEAARLK LTVSPLPAAE PTSEGQPRPA SGRTPPMAQR PDKQTVPATR
FAPAPTHETI TLPAASTAAI RLEIKAISDL SYPMAHCRIP VVDQVTIDGV TEDLRGAVLR
VDVVSATGSH GGPRELHVDL AAGKPTILRD VDLALDPASM LTVDDQRPGR IEAVLHDAAG
EVIAKGFNEV NILAANQWKA TPLHLGLEML AAHIQPNASA ISGLMPDVSD RLNAATGRSA
IDGYQSESPE RADAIAQAVY DAMRARDIRY AEPPASWGLD GQKIRTPHEV LDDRLGTCLD
TAVTMAAALE QAGINTTLWV LKGHALLGYW RVDAALPAIS TTEVIDVANL VDLGQIRLVE
TTMLAGGDDS SPFPDAVGAG RRHLGDDLSN VFGVTDIRQA RLSRIYPLPS RTLSPDGSVV
VTEYTPAEGP AIAPYQRSDS SATVSHQTDS VPLRVAKWKN ALLDLSLRNK LINYTDRAGY
RVEIPGPALG RFEDAVNDNA RITLLASDAV KEIDVARGIR YGRDLPERER ELLLAEKNSA
YIDITGAAYK TKLRYLAAKA KTIVEETGSN NLYLTFGMLN WRFDDRELRS PLVLVPVTLS
TANRGERYTL ALDETGASTP NYCLVEKLRV SFGLEVPDLK EPTHDASGID LAATFNAVRR
AITRAGLHFR VEETTHLAIL QFAKFPLWKD LDNSWKALSS NSLVRHLIDS PDKPFTDPVA
GSTEVDLDRL GDEMPVSADS SQLQAIAQAA AGRTFVLEGP PGTGKSQTIT NLLAHAMAAG
RRVLFVAEKR AALDVVKKRL QAVGLGELSL DLHDKSSRPA AVREQIRAAL DLSVSADTDS
LRTQTEAAES SRNALARYAR RLHEENAARM SLYSARTAEL AADQDVAPIE VPKELVAGGP
SETLHALQQV MRKLPEVADL AQPSIDHPWG FIDSPPAESE VAEIHRCAVE FDSALAAGVE
CGLTIDSLGR CGLLAGFDSW VKLCGAPRHP LSALDTLHEG AWAQELASLD ADLHTLTQRT
PEWRSVASVD AVDLDIPAIH SAAVAADESK LFGRKKRRRA VLEQLSDVLV VDPKTIDLKT
LTSLVTGILE AHAAVAGLRG RVARIPATVI GEPWNPLVPE HTAKVRQQLG WLRWTAALLS
AQPNDPHIDD LRSYYANQPV GAFASQLARI PSAWSALTKT TETSSERQNE WAQPQSFIVH
WWAMRSARRL DDTASIEHWA ALLHLIEPLK PAGMSAVRTA ILNGEIDPDD ASLAFARGIA
VASVAERRDA TALGSFNAEA HDKTVERYTK SLRAIRGELP RAIPAALLHK RRFDANSASG
QIGGLRRQLD RRRGGMSVRG LIEHYGELIT QIMPCTMMSP DSVARFFPAR PDLFDIVVFD
EASQIRVADA IGAMGRSRSV VVVGDSKQMP PTSFAEANAN VDDADDTDQE FFLDEESILT
ECVHAQLPQQ WLSWHYRSQD EALIAFSNQH YYNRRLASFP APRSGGASDA GGQGISLIRV
NGTFERSGKG KTLRTNRVEA DAIVDDVARR FEQSPDAVPS LGIITFNAQQ RDLIDNLLRD
SADERVVRAL DEPDGLFVKN LENVQGDERD TILFSVAFSA KEKGVVPLNF GPLSRPGGER
RLNVAITRAR REVVLYASFD AEDLRAEETS QIGTKHLKAY LEMAARGVDD VADSMRRTPV
IDRHRDDIAA ALRDAGLVVT TDLGLSDFRV DLVLGDPTEP ERQLVAVLLD GQSWRARRTV
ADRDALPVDV LRDLMHWPAI ERVWLPEWLR RPEHVVAQLK ESVDVARQRV LSGNFRAETT
APVPSPAPPR QATPLLRASQ PAKPATAAAQ SHPMVQVYHE WKPGRLGDVT VLDDLPIAYA
KSRVYDAIIS AMAAEAPIHP RRLTKLVAAA FNLTRLNENR HRSIEYVVPV DYRRPTGEGF
YWPVGVEPED WRIVRRPPEG TSRQLDHVSL IEIGNAMIVV AEQTGGIETY DLKREALNLL
GGRRVTQQIE ARLNDALNKA LERKVLHQNG SGLITSAVLH LSGAAESAQT
//
