ID I2CYY9_MACMU Unreviewed; 931 AA.
AC I2CYY9;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Serine/threonine-protein phosphatase 6 regulatory subunit 2 isoform 3 {ECO:0000313|EMBL:AFJ72174.1};
GN Name=PPP6R2 {ECO:0000313|EMBL:AFJ72174.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:AFJ72174.1};
RN [1] {ECO:0000313|EMBL:AFJ72174.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:AFJ72174.1};
RX PubMed=25319552; DOI=10.1186/1745-6150-9-20;
RA Zimin A.V., Cornish A.S., Maudhoo M.D., Gibbs R.M., Zhang X., Pandey S.,
RA Meehan D.T., Wipfler K., Bosinger S.E., Johnson Z.P., Tharp G.K.,
RA Marcais G., Roberts M., Ferguson B., Fox H.S., Treangen T., Salzberg S.L.,
RA Yorke J.A., Norgren R.B.Jr.;
RT "A new rhesus macaque assembly and annotation for next-generation
RT sequencing analyses.";
RL Biol. Direct 9:20-20(2014).
CC -!- SIMILARITY: Belongs to the SAPS family.
CC {ECO:0000256|ARBA:ARBA00006180}.
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DR EMBL; JV667511; AFJ72174.1; -; mRNA.
DR RefSeq; XP_015006167.1; XM_015150681.1.
DR AlphaFoldDB; I2CYY9; -.
DR GO; GO:0019903; F:protein phosphatase binding; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR007587; SAPS.
DR PANTHER; PTHR12634:SF15; SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY SUBUNIT 2; 1.
DR PANTHER; PTHR12634; SIT4 YEAST -ASSOCIATING PROTEIN-RELATED; 1.
DR Pfam; PF04499; SAPS; 2.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 2: Evidence at transcript level;
FT REGION 409..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 632..680
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 737..767
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 785..829
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..423
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..439
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 931 AA; 101268 MW; E4B0B51BB54CE0A7 CRC64;
MFWKFDLNTT SHVDKLLDKE HVTLQELMDE DDILQECKAQ NQKLLDFLCR QQCMEELVSL
ITQDPPLDME EKVRFKYPNT ACELLTCDVP QISDRLGGDE SLLSLLYDFL DHEPPLNPLL
ASFFSKTIGN LIARKTEQVI TFLKKKDKFI SLVLKHIGTS ALMDLLLRLV SCVEPAGLRQ
EVLHWLNEEK VIQRLVELIH PSQDEDRQSN ASQTLCDIVR LGRDQGSQLQ EALEPDPLLT
ALESQDCVEQ LLKNMFDGDR TESCLVSGTQ VLLTLLETRR VGTEGLVDSF SQGLERSYTV
SSSVLHGIEP RLKDFHQLLL NPPKKKAILT TIGVLEEPLG NARLHGARLM AALLHTNTPS
INQELCRLNT MDLLLDLFFK YTWNNFLHFQ VELCIAAILS HAAREDRTEA SGSESRAEPL
HENGNRSLET PQPPASLPDN TMVTHLFQKC CLVQRILEAW EANDHTQAAG GMRRGNMGHL
TRIANAVVQN LERGPVQTHI SEVIRGLPAD CRGRWESFVE ETLTETNRRN TVDLAFSDYQ
IQQMAASFVD QFGFNDEEFA DQDDNINAPF DRIAEINFNI DADEDSPSAA LFEACCSDRI
QPFDDDEDED IWEDSDTRCA TRVMARARFG APHASDSCSK NGPERGGQDG KASSEAHGDA
PGAGAPLAPG KKEAPTVEGD SEGAMWTAVF DEPVNSTPTA PGVVRDVGAS VWAAGTSAPE
EKGWAKFTDF QPFCCSESGP RCSSPVDTER SRAEGSRSQG PEKAFSPASP CAWNVCVTRK
APLLASDSSS SGGSDSEDYQ KAASAVDAVS RSPGREAPPR PTGARTEEAV GRAVCANSRL
LDPACPAPKE VTAAPAMAPP PEAAVAITTA LSKAGPAIPS PAVSSAVAVA VPLGPIMAVT
TAPAMVATLG TVTKDGKRDA PPEGAALNGP V
//
